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47 results on '"super-enhancers"'

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1. Histone H3.3 K27M chromatin functions implicate a network of neurodevelopmental factors including ASCL1 and NEUROD1 in DIPG

2. NSMCE2, a novel super-enhancer-regulated gene, is linked to poor prognosis and therapy resistance in breast cancer.

3. Etiology of super-enhancer reprogramming and activation in cancer

4. Transcription factor condensates and signaling driven transcription

5. Endodermal Maternal Transcription Factors Establish Super-Enhancers during Zygotic Genome Activation

6. Histone H3.3 K27M chromatin functions implicate a network of neurodevelopmental factors including ASCL1 and NEUROD1 in DIPG

7. Mapping the evolving landscape of super-enhancers during cell differentiation

8. HDAC4 degradation during senescence unleashes an epigenetic program driven by AP-1/p300 at selected enhancers and super-enhancers

9. A systematic dissection of the epigenomic heterogeneity of lung adenocarcinoma reveals two different subclasses with distinct prognosis and core regulatory networks

10. Super-Enhancers, Phase-Separated Condensates, and 3D Genome Organization in Cancer.

11. Chromatin profiling reveals relocalization of lysine-specific demethylase 1 by an oncogenic fusion protein

12. An intriguing characteristic of enhancer-promoter interactions

13. A holistic view of mouse enhancer architectures reveals analogous pleiotropic effects and correlation with human disease

14. Chromatin structure regulates cancer-specific alternative splicing events in primary HPV-related oropharyngeal squamous cell carcinoma

15. A Comparative Analysis of Super-Enhancers and Broad H3K4me3 Domains in Pig, Human, and Mouse Tissues

16. Cis-acting super-enhancer lncRNAs as biomarkers to early-stage breast cancer.

17. CHROMATIX: computing the functional landscape of many-body chromatin interactions in transcriptionally active loci from deconvolved single cells

18. Super-enhancers are transcriptionally more active and cell type-specific than stretch enhancers

19. BET-Independent Murine Leukemia Virus Integration Is Retargeted In Vivo and Selects Distinct Genomic Elements for Lymphomagenesis

20. Epigenetics of Skeletal Muscle-Associated Genes in the ASB, LRRC, TMEM, and OSBPL Gene Families

21. HDAC4 degradation during senescence unleashes an epigenetic program driven by AP-1/p300 at selected enhancers and super-enhancers

22. Disruption of Broad Epigenetic Domains in PDAC Cells by HAT Inhibitors

23. Epigenetics and expression of key genes associated with cardiac fibrosis: NLRP3, MMP2, MMP9, CCN2/CTGF and AGT

24. Mapping the evolving landscape of super-enhancers during cell differentiation

25. The Role of rDNA Clusters in Global Epigenetic Gene Regulation

26. Activation-induced deaminase is critical for the establishment of DNA methylation patterns prior to the germinal center reaction

27. A systematic dissection of the epigenomic heterogeneity of lung adenocarcinoma reveals two different subclasses with distinct prognosis and core regulatory networks

28. An intriguing characteristic of enhancer-promoter interactions

29. Profiling of H3K27Ac Reveals the Influence of Asthma on the Epigenome of the Airway Epithelium

30. A holistic view of mouse enhancer architectures reveals analogous pleiotropic effects and correlation with human disease

31. An atlas of dynamic chromatin landscapes in mouse fetal development

32. Enhancer mapping uncovers phenotypic heterogeneity and evolution in patients with luminal breast cancer

33. An enhancer cluster controls gene activity and topology of the SCN5A-SCN10A locus in vivo

34. Human pancreatic islet three-dimensional chromatin architecture provides insights into the genetics of type 2 diabetes

35. Disruption of Broad Epigenetic Domains in PDAC Cells by HAT Inhibitors

36. Super-Enhancers at the Nanog Locus Differentially Regulate Neighboring Pluripotency-Associated Genes

37. Nuclear transcriptome profiling of induced pluripotent stem cells and embryonic stem cells identify non-coding loci resistant to reprogramming

38. Variants in genes encoding small GTPases and association with epithelial ovarian cancer susceptibility

39. Activation-induced cytidine deaminase targets SUV4-20-mediated histone H4K20 trimethylation to class-switch recombination sites

40. Differential epigenetic reprogramming in response to specific endocrine therapies promotes cholesterol biosynthesis and cellular invasion

41. Spatial enhancer clustering and regulation of enhancer-proximal genes by cohesin

42. Integrative analysis of public ChIP-seq experiments reveals a complex multi-cell regulatory landscape

43. An environment-dependent transcriptional network specifies human microglia identity

44. The Developmental Potential of iPSCs Is Greatly Influenced by Reprogramming Factor Selection

45. Pancreatic islet enhancer clusters enriched in type 2 diabetes risk-associated variants

46. High-density P300 enhancers control cell state transitions

47. Genome-wide identification and characterisation of HOT regions in the human genome

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