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Your search keyword '"Morona, Judy K."' showing total 4 results
Start Over Author "Morona, Judy K." Topic genetic mutation
4 results on '"Morona, Judy K."'

3. Identification of Streptococcus pneumoniae Cps2C Residues That Affect Capsular Polysaccharide Polymerization, Cell Wall Ligation, and Cps2D Phosphorylation.

Author

Byrne, James P., Morona, Judy K., Paton, James C., and Morona, Renato

Subjects
*STREPTOCOCCUS pneumoniae, *POLYSACCHARIDES, *POLYMERIZATION, *BACTERIAL cell walls, *PHOSPHORYLATION, *GENETIC mutation
Abstract

A number of single amino acid substitutions throughout Streptococcus pneumoniae Cps2C were found to affect its function and confer either a mucoid or a small colony phenotype. These mutants exhibit significant changes in capsular polysaccharide (CPS) profile relative to that of wild-type pneumococci. The introduced mutations affect either polymerization or ligation of CPS to the cell wall and/or Cps2D phosphorylation. [ABSTRACT FROM AUTHOR]

Published
2011
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4. Streptococcus pneumoniae Capsule Biosynthesis Protein CpsB Is a Novel Manganese—Dependent....

Author

Morona, Judy K., Morona, Renato, Miller, David C., and Paton, James C.

Subjects
*STREPTOCOCCUS pneumoniae, *PROTEIN synthesis, *PHOSPHATASES, *DISEASES, *GENETIC mutation
Abstract

Examines the Streptococcus pneumoniae (S. pneumoniae) capsule biosynthesis protein, a manganese-dependent phosphotyrosine-protein phosphatase. Recognition of S. pneumoniae as the cause of invasive diseases in humans; Capacity of S. pneumoniae to produce a polysaccharide capsule; Construction of S. pneumoniae containing a defined mutation.

Published
2002
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