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24 results on '"Zhen-jie Wu"'

18. Expression of eukaryotic elongation factor 1A1 in renal cell carcinoma of T 1 N 0 M 0 stage and its relationship with prognosis

Author

Zhen-jie Wu, Li Gao, Lin-hui Wang, Peng Li, Bing Liu, Junming Chen, Yi Bao, Qing Yang, and Zhi-xiang Wang

Subjects
Pathology, medicine.medical_specialty, medicine.medical_treatment, Pathological staging, Cell, General Medicine, Biology, medicine.disease, Nephrectomy, medicine.anatomical_structure, Renal cell carcinoma, Clear cell carcinoma, medicine, Survival rate, Grading (tumors), Survival analysis
Abstract

Objective To study the expression of eukaryotic elongation factor 1A1(eEF1A1)in T1N0M0 renal cancer tissues and its relationship with patient prognosis.Methods The tissue specimens of patients with renal cell carcinoma who received radical nephrectomy in Shanghai Changhai Hospital in 2007 were collected.Inclusion criteria were:no treatments before surgery,T1N0M0 stage,clear cell carcinoma and with complete follow-up data.Immunohistochemical staining was used to examine the expression of eEF1A1 in the cancerous tissues,and we then established the relationship of eEF1A1 expression with Fuhrman pathological grading and patient prognosis.The relationship between Fuhrman grading pathological staging and eEF1A1 expression was investigated by drawing crosstabs,chi-square test,and Fisher's exact test.Kaplan-Meier survival curves and log-rank test were used to study the relationship between eEF1A1 and prognosis of patients with T1N0M0 renal cell carcinoma.Results The patients were followed up for 4-95 months,averagely(77.9±18.3)months;the overall survival rate of patients was 88.6% and the progression-free survival rate was 80.0% during the follow-up period.Immunohistochemistry showed eEF1A1 was highly expressed in 61.4% of renal cell carcinoma tissues and in tissues of high Fuhrman grade(P=0.004).Survival analysis showed patients with low expression of eEF1A1 in renal cell carcinoma tissue had significantly longer survival(P=0.019),and all the patients with low expression survived in our study.Conclusion Expression of eEF1A1 in T1N0M0renal cell carcinoma tissue is associated with Fuhrman grades and prognosis,with low expression indicating a better prognosis.

Published
2015

19. Expression of CXCR3 in renal cell carcinoma and its significance

Author

Zhen-jie Wu, Hai-bo Sheng, Zun-li Xu, Lin-hui Wang, Wei Chen, Qing Yang, and Bing Liu

Subjects
Expression (architecture), Renal cell carcinoma, business.industry, medicine, Cancer research, General Medicine, medicine.disease, business, CXCR3
Published
2013

20. Robotic-assisted laparoscopic nephrectomy (right) combined with inferior vena caval thrombectomy for level Ⅱ tumor thrombus：the first clinical case in China

Author

Zhiqing Zhao, Chen Lv, Li Song, Liang Xiao, Lin-hui Wang, Ming-min Li, Meng-lu Xu, Xia Sheng, Zhen-jie Wu, Yinghao Sun, Hua-mao Ye, and Guo-jun Shen

Subjects
Inferior vena caval, medicine.medical_specialty, Tumor thrombus, business.industry, Robotic assisted, medicine, Laparoscopic nephrectomy, General Medicine, Clinical case, Level ii, business, Surgery
Published
2014

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