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Your search keyword '"Jose María García-Prim"' showing total 3 results
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3 results on '"Jose María García-Prim"'

1. Impact of neoadjuvant therapy on postoperative complications in non-small-cell lung cancer patients subjected to anatomic lung resection

Author

Alberto Cabañero Sánchez, Gemma María Muñoz Molina, Sara Fra Fernández, Alfonso Muriel García, Angel Cilleruelo Ramos, Néstor Martínez Hernández, Florentino Hernando Trancho, Nicolás Moreno Mata, Borja Aguinagalde de Valiente, Sergio Amor Alonso, Miguel Jesús Arrarás, Ana Isabel Blanco Orozco, Marc Boada Collado, Sergio Bolufer Nadal, Isabel Cal Vázquez, Sergi Call Caja, Ángel Cilleruelo Ramos, Miguel Congregado Loscertales, Silvana Crowley Carrasco, Raúl Embún Flor, Elena Fernández Martín, Juan José Fibla Alfara, Santiago García Barajas, Maria Dolores García Jiménez, Jose María García Prim, Jose Alberto García Salcedo, Carlos Fernando Giraldo Ospina, David Gómez de Antonio, María Teresa Gómez Hernández, Juan José Gelbenzu Zazpe, Jorge Henández Ferrández, Jennifer D. Illana Wolf, Alberto Jauregui Abularach, Marcelo Jiménez López, Unai Jiménez Maestre, Cipriano López García, Iker López Sanz, Elisabeth Martínez Téllez, Lucía Milla Collado, Roberto Mongil Poce, Francisco Javier Moradiellos Díez, Ramón Moreno Balsalobre, Sergio B. Moreno Merino, Carme Obiols Fornell, Florencio Quero Valenzuela, María Elena Ramírez Gil, Ricard Ramos Izquierdo, José Luis Recuero Díaz, Eduardo Rivo Vázquez, Alberto Rodríguez Fuster, Rafael Rojo Marcos, Iñigo Royo Crespo, David Sánchez Lorente, Laura Sanchez Moreno, Julio Sesma Romero, Carlos Simón Adiego, and Juan Carlos Trujillo Reyes

Subjects
Lung Neoplasms, Postoperative Complications, Treatment Outcome, Oncology, Carcinoma, Non-Small-Cell Lung, Humans, Surgery, Chemoradiotherapy, General Medicine, Pneumonectomy, Lung, Neoadjuvant Therapy
Abstract

To study the impact of neoadjuvant therapies on postoperative complications and mortality among non-small-cell lung cancer (NSCLC) patients subjected to anatomic lung resection and included in the Spanish cohort of the video-assisted thoracic surgery (GE-VATS) multicenter database.The study included a total of 3085 patients from 33 centers between December 2016 and March 2018. We performed a comparative analysis of the complications and mortality in patients who received neoadjuvant therapies (n = 263) versus those who did not (n = 2822). A propensity score-matched analysis was used to adjust for potential confounders. Association between exposure in two groups and outcomes were estimated by logistic regression weighted by inverse of probability of receiving the treatment that actually received.In the unadjusted analysis, the chemotherapy (CT) and chemoradiotherapy (CRT) group presented a higher frequency of ICU readmissions, reinterventions, empyema, cardiovascular complications, a greater frequency of atrial fibrillation, and an increased need for blood product transfusions. In the adjusted group, CT and CRT patients had a higher rate of cardiovascular complications (CT p = 0.002; OR 2.29; 95% CI 1.34-3.94 and CRT p = 0.001; OR 2.90; 95% CI 1.52-5-52), arrhythmias (CT p = 0.013; OR 2.23; 95% CI 1.18-4.20 and CRT p = 0.046; OR 2.22; 95% CI 1.01-4.90) and transfussions (CT p = 0.042; OR 2.95; 95% CI 1.04-8.35 and CRT p 0.001; OR 7.74; 95% CI 3.01-19-92).Based on our series, neoadjuvant CT and CRT were associated with a higher rate of cardiovascular complications, arrhythmias and transfussions in patients with NSCLC subjected to anatomic lung resection.

Published
2022

2. VATS lobectomy morbidity and mortality is lower in patients with the same ppoDLCO: Analysis of the database of the Spanish Video-Assisted Thoracic Surgery Group

Author

Borja Aguinagalde, Asier Insausti, Iker Lopez, Laura Sanchez, Sergio Bolufer, Raul Embun, Iñigo Royo-Crespo, José Luis Recuero Díaz, Sergi Call, Miguel Congregado, David Gómez-de Antonio, Marcelo F. Jimenez, Nicolas Moreno-Mata, Sergio Amor-Alonso, Miguel Jesús Arrarás, Ana Isabel Blanco Orozco, Marc Boada, Alberto Cabañero Sánchez, Isabel Cal Vázquez, Ángel Cilleruelo Ramos, Silvana Crowley Carrasco, Elena Fernández-Martín, Santiago García-Barajas, Maria Dolores García-Jiménez, Jose María García-Prim, Jose Alberto Garcia-Salcedo, Juan José Gelbenzu-Zazpe, Carlos Fernando Giraldo-Ospina, María Teresa Gómez Hernández, Jorge Hernández, Jennifer D. Illana Wolf, Alberto Jauregui Abularach, Unai Jiménez, Iker López Sanz, Néstor J. Martínez-Hernández, Elisabeth Martínez-Téllez, Lucía Milla Collado, Roberto Mongil Poce, Francisco Javier Moradiellos-Díez, Ramón Moreno-Balsalobre, Sergio B. Moreno Merino, Carme Obiols, Florencio Quero-Valenzuela, María Elena Ramírez-Gil, Ricard Ramos-Izquierdo, Eduardo Rivo, Alberto Rodríguez-Fuster, Rafael Rojo-Marcos, David Sanchez-Lorente, Laura Sanchez Moreno, Carlos Simón, Juan Carlos Trujillo-Reyes, Florentino Hernando Trancho, Cipriano López, Juan José Fibla, and Julio Sesma

Subjects
Lung cancer surgery, medicine.medical_specialty, Lung Neoplasms, business.industry, Thoracic Surgery, Video-Assisted, medicine.medical_treatment, VATS lobectomy, General Medicine, medicine.disease, Surgery, Treatment Outcome, Thoracotomy, Cardiothoracic surgery, Relative risk, Propensity score matching, medicine, Risk of mortality, Humans, Morbidity, Lung cancer, business, Pneumonectomy, Retrospective Studies
Abstract

Measuring predicted post-operative diffusion capacity of the lung for carbon monoxide (ppoDLCO) is essential to determine patient operability and to stratify the risk of patients who are candidates for major lung cancer surgery. Studies that established surgical risk variables were based on open surgery series. The aim of our study was to analyze morbidity and mortality as a function of ppoDLCO and to compare its behavior in open and video-assisted thoracic surgery (VATS).We compared 90-day mortality and morbidity in patients undergoing open surgery versus VATS as a function of decline in ppoDLCO. Propensity score matching (using age, ASA, arterial vascular disease, BMI, gender, stage, ppoDLCO, and ppoFEVOf 2,530 patients with lung cancer and ppoDLCO values, a sample of 1,624 (812 per group) was obtained after score matching. The relative risk of mortality associated with thoracotomy in patients with ppoDLCO 60 is 2.66 (p 0.02) compared to VATS. The risk of thoracotomy in terms of overall and cardiac and respiratory morbidity is higher than that of VATS for almost all ppoDLCO values.Major resection by VATS shows lower morbidity and mortality in patients with the same ppoDLCO. A steady rise in the risk of mortality begins to occur at higher ppoDLCO values in thoracotomy (∼60) than in VATS (∼45).

Published
2020

3. Spanish Video-Assisted Thoracic Surgery Group: Method, Auditing, and Initial Results From a National Prospective Cohort of Patients Receiving Anatomical Lung Resections

Author

Silvana Crowley Carrasco, Eduardo Rivo, Santiago García-Barajas, Borja Aguinagalde, Alberto Cabañero Sánchez, Lucía Milla Collado, Sergi Call, Carlos Fernando Giraldo-Ospina, Nicolas Moreno-Mata, Juan José Gelbenzu-Zazpe, Florentino Hernando Trancho, David Sánchez-Lorente, Marcelo F. Jiménez, Ramón Moreno-Balsalobre, Laura Sanchez Moreno, Alberto Rodríguez-Fuster, Ana Isabel Blanco Orozco, Rafael Rojo-Marcos, María Elena Ramírez-Gil, Francisco Javier Moradiellos-Díez, Unai Jiménez, Sergio B. Moreno Merino, María Dolores García-Jiménez, Elena Fernández-Martín, Jose María García-Prim, Florencio Quero-Valenzuela, Miguel Congregado, Iñigo Royo-Crespo, Carme Obiols, Ángel Cilleruelo Ramos, Sergio Bolufer, Isabel Vazquez, Juan Carlos Trujillo-Reyes, Iker López Sanz, Jennifer D. Illana Wolf, Jose Alberto Garcia-Salcedo, Miguel Jesús Arrarás, Marc Boada, David Gómez de Antonio, Sergio Amor-Alonso, Raul Embun, José Luis Recuero Díaz, Alberto Jauregui Abularach, Ricard Ramos-Izquierdo, María Teresa Gómez Hernández, Roberto Mongil Poce, Néstor J. Martínez-Hernández, Carlos Simón, Jorge Hernández, Elisabeth Martínez-Téllez, [Embun, Raul] Hosp Univ Miguel Servet, Serv Cirugia Torac, Zaragoza, Spain, [Royo-Crespo, Inigo] Hosp Univ Miguel Servet, Serv Cirugia Torac, Zaragoza, Spain, [Recuero Diaz, Jose Luis] Hosp Univ Miguel Servet, Serv Cirugia Torac, Zaragoza, Spain, [Embun, Raul] Hosp Clin Univ Lozano Blesa, IIS Aragon, Zaragoza, Spain, [Royo-Crespo, Inigo] Hosp Clin Univ Lozano Blesa, IIS Aragon, Zaragoza, Spain, [Recuero Diaz, Jose Luis] Hosp Clin Univ Lozano Blesa, IIS Aragon, Zaragoza, Spain, [Bolufer, Sergio] Hosp Gen Univ Alicante, Serv Cirugia Torac, Alicante, Spain, [Call, Sergi] Univ Barcelona, Hosp Univ Mutua Terrasa, Serv Cirugia Torac, Barcelona, Spain, [Obiols, Carme] Univ Barcelona, Hosp Univ Mutua Terrasa, Serv Cirugia Torac, Barcelona, Spain, [Congregado, Miguel] Hosp Univ Virgen Macarena, Serv Cirugia Torac, Seville, Spain, [Moreno Merino, Sergio B.] Hosp Univ Virgen Macarena, Serv Cirugia Torac, Seville, Spain, [Gomez-de Antonio, David] Hosp Univ Puerta Hierro Majadahonda, Serv Cirugia Torac, Madrid, Spain, [Crowley Carrasco, Silvana] Hosp Univ Puerta Hierro Majadahonda, Serv Cirugia Torac, Madrid, Spain, [Jimenez, Marcelo F.] Univ Salamanca, Hosp Univ Salamanca, Serv Cirugia Torac, IBSAL, Salamanca, Spain, [Gomez Hernandez, Maria Teresa] Univ Salamanca, Hosp Univ Salamanca, Serv Cirugia Torac, IBSAL, Salamanca, Spain, [Moreno-Mata, Nicolas] Hosp Univ Ramon Y Cajal, Serv Cirugia Torac, Madrid, Spain, [Cabanero Sanchez, Alberto] Hosp Univ Ramon Y Cajal, Serv Cirugia Torac, Madrid, Spain, [Aguinagalde, Borja] Hosp Univ Donostia, Serv Cirugia Torac, San Sebastian, Spain, [Lopez Sanz, Iker] Hosp Univ Donostia, Serv Cirugia Torac, San Sebastian, Spain, [Amor-Alonso, Sergio] Hosp Univ Quironsalud Madrid, Serv Cirugia Torac, Madrid, Spain, [Javier Moradiellos-Diez, Francisco] Hosp Univ Quironsalud Madrid, Serv Cirugia Torac, Madrid, Spain, [Jesus Arraras, Miguel] Fdn Inst Valenciano Oncol, Serv Cirugia Torac, Valencia, Spain, [Blanco Orozco, Ana Isabel] Hosp Univ Virgen Rocio, Serv Cirugia Torac, Seville, Spain, [Boada, Marc] Univ Barcelona, Hosp Clin Barcelona, Inst Resp, Serv Cirugia Torac, Barcelona, Spain, [Sanchez-Lorente, David] Univ Barcelona, Hosp Clin Barcelona, Inst Resp, Serv Cirugia Torac, Barcelona, Spain, [Cal Vazquez, Isabel] Hosp Univ La Princesa, Serv Cirugia Torac, Madrid, Spain, [Moreno-Balsalobre, Ramon] Hosp Univ La Princesa, Serv Cirugia Torac, Madrid, Spain, [Cilleruelo Ramos, Angel] Hosp Clin Univ, Serv Cirugia Torac, Valladolid, Spain, [Fernandez-Martin, Elena] Hosp Clin San Carlos, Serv Cirugia Torac, Madrid, Spain, [Hernando Trancho, Florentino] Hosp Clin San Carlos, Serv Cirugia Torac, Madrid, Spain, [Garcia-Barajas, Santiago] Hosp Univ Badajoz, Serv Cirugia Torac, Badajoz, Spain, [Dolores Garcia-Jimenez, Maria] Hosp Univ Albacete, Serv Cirugia Torac, Albacete, Spain, [Maria Garcia-Prim, Jose] Hosp Univ Santiago de Compostela, Serv Cirugia Torac, Santiago De Compostela, Spain, [Rivo, Eduardo] Hosp Univ Santiago de Compostela, Serv Cirugia Torac, Santiago De Compostela, Spain, [Alberto Garcia-Salcedo, Jose] Hosp Univ 12 Octubre, Serv Cirugia Torac, Madrid, Spain, [Gelbenzu-Zazpe, Juan Jose] Complejo Hosp Navarra, Serv Cirugia Torac, Pamplona, Spain, [Elena Ramirez-Gil, Maria] Complejo Hosp Navarra, Serv Cirugia Torac, Pamplona, Spain, [Fernando Giraldo-Ospina, Carlos] Hosp Reg Univ, Serv Cirugia Torac, Malaga, Spain, [Mongil Poce, Roberto] Hosp Reg Univ, Serv Cirugia Torac, Malaga, Spain, [Hernandez, Jorge] Hosp Univ Sagrat Cor, Serv Cirugia Torac, Barcelona, Spain, [Illana Wolf, Jennifer D.] Hosp Puerta Mar, Serv Cirugia Torac, Cadiz, Spain, [Jauregui Abularach, Alberto] Hosp Univ Vall dHebron, Serv Cirugia Torac, Barcelona, Spain, [Jimenez, Unai] Hosp Univ Cruces, Serv Cirugia Torac, Bilbao, Spain, [Rojo-Marcos, Rafael] Hosp Univ Cruces, Serv Cirugia Torac, Bilbao, Spain, [Martinez-Hernandez, Nestor J.] Hosp Univ La Ribera, Serv Cirugia Torac, Valencia, Spain, [Martinez-Tellez, Elisabeth] Univ Autonoma Barcelona, Serv Cirugia Torac, Hosp Santa Creu & St Pau, Barcelona, Spain, [Carlos Trujillo-Reyes, Juan] Univ Autonoma Barcelona, Serv Cirugia Torac, Hosp Santa Creu & St Pau, Barcelona, Spain, [Milla Collado, Lucia] Hosp Arnau Vilanova, Serv Cirugia Torac, Lleida, Spain, [Quero-Valenzuela, Florencio] Hosp Virgen Nieves, Serv Cirugia Torac, Granada, Spain, [Ramos-Izquierdo, Ricard] Hosp Univ Bellvitge, Serv Cirugia Torac, Barcelona, Spain, [Rodriguez-Fuster, Alberto] Hosp Mar, Serv Cirugia Torac, Barcelona, Spain, [Rodriguez-Fuster, Alberto] IMIM Inst Invest Med Hosp Mar, Barcelona, Spain, [Sanchez Moreno, Laura] Hosp Univ Marques Valdecilla, Serv Cirugia Torac, Santader, Spain, [Simon, Carlos] Hosp Univ Gregorio Maranon, Serv Cirugia Toroc, Madrid, Spain, and Spanish Society of Thoracic Surgery as the best national research project of 2015

Subjects
Pulmonary and Respiratory Medicine, medicine.medical_specialty, Lung resections, media_common.quotation_subject, Video-assisted thoracic surgery, VATS, Audit, Outcomes, Multicentre study, 03 medical and health sciences, 0302 clinical medicine, Cancer surgery, European-society, medicine, Mortality, Lung cancer, Prospective cohort study, media_common, Selection bias, Auditoria, business.industry, General surgery, Thoracoscopy, Auditing, Perioperative, General Medicine, medicine.disease, Thoracic surgery, 030228 respiratory system, Cohort, Lobectomy, Càncer de pulmó, Cirurgia toràcica, business, Cohort study
Abstract

Introduction: Our study sought to know the current implementation of video-assisted thoracoscopic surgery (VATS) for anatomical lung resections in Spain. We present our initial results and describe the auditing systems developed by the Spanish VATS Group (GEVATS). Methods: We conducted a prospective multicentre cohort study that included patients receiving anatomical lung resections between 12/20/2016 and 03/20/2018. The main quality controls consisted of determining the recruitment rate of each centre and the accuracy of the perioperative data collected based on six key variables. The implications of a low recruitment rate were analysed for "90-day mortality" and "Grade IIIb-V complications". Results: The series was composed of 3533 cases (1917 VATS; 54.3%) across 33 departments. The centres' median recruitment rate was 99% (25-75th:76-100%), with an overall recruitment rate of 83% and a data accuracy of 98%. We were unable to demonstrate a significant association between the recruitment rate and the risk of morbidity/mortality, but a trend was found in the unadjusted analysis for those centres with recruitment rates lower than 80% (centres with 95-100% rates as reference): grade IIIb-V OR= 0.61 (p = 0.081), 90-day mortality OR = 0.46 (p = 0.051). Conclusions: More than half of the anatomical lung resections in Spain are performed via VATS. According to our results, the centre's recruitment rate and its potential implications due to selection bias, should deserve further attention by the main voluntary multicentre studies of our speciality. The high representativeness as well as the reliability of the GEVATS data constitute a fundamental point of departure for this nationwide cohort. (C) 2020 SEPAR. Published by Elsevier Espana, S.L.U. All rights reserved.

Published
2019

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