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espanolLa presente investigacion fue ejecutada durante el ano 2020, tuvo como finalidad determinar la influencia del sistema web en el proceso de incidencias de la empresa RR&C Grupo Tecnologico S.A.C., el diseno empleado en la investigacion fue experimental del tipo preexperimental, la metodologia que se aplico en el estudio fue aplicada y de enfoque cuantitativo. Ademas, la tecnica empleada para la recoleccion de datos fue la observacion y el instrumento usado fue la guia de observacion de campo, los cuales fueron validados por expertos. Para el caso de la muestra estuvo conformada por 20 incidencias por cada uno de los indicadores. Y los resultados conseguidos en la investigacion fueron: para el primer indicador se logro incrementar la tasa promedio de resolucion de incidencias en el pretest de un valor de 61.48% a un valor de 87.00% luego del postest y para el segundo indicador se logro reducir la tasa promedio de incidencias reabiertas en el pretest de un valor de 16.80% a un valor de 8.35% despues del postest. De tal forma, se concluyo que el sistema informatico mejoro positivamente el proceso de incidencias en la compania RR&C Grupo Tecnologico S.A.C. EnglishThe present investigation was carried out during the year 2020, its purpose was to determine the influence of the web system in the process of incidents of the company RR&C Grupo Tecnologico S.A.C., the design used in the research was experimental of the pre-experimental type, the methodology applied in the study was applied and of quantitative approach. In addition, the technique used for data collection was observation and the instrument used was the field observation guide, which was validated by experts. The sample consisted of 20 incidents for each of the indicators. And the results achieved in the research were: for the first indicator, the average rate of incident resolution in the pretest was increased from a value of 61.48% to a value of 87.00% after the postest, and for the second indicator, the average rate of reopened incidents in the pretest was reduced from a value of 16.80% to a value of 8.35% after the postest. Thus, it was concluded that the computer system positively improved the process of incidents in the company RR&C Grupo Tecnologico S.A.C.

Institutional Review Board Statement: The study was conducted according to the guidelines of the Declaration of Helsinki, and approved by the Ethics Committee of the Andalusian Health Service (LUNG CA SURV 2180-N-20)., Data Availability Statement: The data presented in this study are available on request from the corresponding author. The data are not publicly available due to ethical., Background: Lung cancer is typically diagnosed in an advanced phase of its natural history. Explanatory models based on epidemiological and clinical variables provide an approximation of patient survival less than one year using information extracted from the case history only, whereas models involving therapeutic variables must confirm that any treatment applied is worse than surgery in survival terms. Models for classifying less than one year survival for patients diagnosed with lung cancer which are able to identify risk factors and quantify their effect for prognosis are analyzed. Method: Two stepwise binary logistic regression models, based on a retrospective study of 521 cases of patients diagnosed with lung cancer in the Interventional Pneumology Unit at the Hospital “Virgen de las Nieves”, Granada, Spain. Results: The first model included variables age, history of pulmonary neoplasm, tumor location, dyspnea, dysphonia, and chest pain. The independent risk factors age greater than 70 years, a peripheral location, dyspnea and dysphonia were significant. For the second model, treatments were also significant. Conclusions: Age, history of pulmonary neoplasm, tumor location, dyspnea, dysphonia, and chest pain are predictors for survival in patients diagnosed with lung cancer at the time of diagnosis. The treatment applied is significant for classifying less than one year survival time which confirms that any treatment is markedly inferior to surgery in terms of survival. This allows to consider applications of more or less aggressive treatments, anticipation of palliative cares or comfort measures, inclusion in clinical trials, etc.

In 2020, the Governments of many countries maintained different levels of confinement of the population due to the pandemic that produced the COVID-19. There are few studies published on the psychological impact in the child and adolescent population diagnosed with mental disorders, especially during the home confinement stage. Explanatory models based on socio-demographic and clinical variables provide an approximation to level changes in different dimensions of behavioural difficulties. A categorical-response logistic ordinal regression model, based on a cross-sectional study with 139 children and adolescents diagnosed with mental disorders is performed for each dimension under analysis. Most of the socio-demographic and clinical explanatory variables considered (24 of 26) were significant at population level for at least one of the four dimensions of behavioural difficulties (15 response variables) under analysis. Odds-ratios were interpreted to identify risk or protective factors increasing or decreasing severity in the response variable. This analysis provides useful information, making it possible to more readily anticipate critical situations due to extreme events, such as a confinement, in this population.

Attention deficit/hyperactivity disorder (ADHD) is one of the most frequent neurodevelopmental disorders in childhood and adolescence. Choosing the right treatment is critical to controlling and improving symptoms. An innovative ADHD treatment is neurofeedback (NF) that trains participants to self-regulate brain activity. The aim of the study was to analyze the effects of NF interventions in children with ADHD. A systematic review was carried out in the CINAHL, Medline (PubMed), Proquest, and Scopus databases, following the PRISMA recommendations. Nine articles were found. The NF improved behavior, allowed greater control of impulsivity, and increased sustained attention. In addition, it improved motor control, bimanual coordination and was associated with a reduction in theta waves. NF combined with other interventions such as medication, physical activity, behavioral therapy training, or attention training with brain–computer interaction, reduced primary ADHD symptoms. Furthermore, more randomized controlled trials would be necessary to determine the significant effects.

Background and objectives: Palliative care (PC) prevents and alleviates patients´ su ering to improve their quality of life in their last days. In recent years, there has been an increase in visits to the emergency services (ES) by patients who may need this type of care. The aims were to describe the training and capacitation of nurses from ES in PC. Accordingly, a systematic review was performed. Materials and Methods: Medline, Scopus, and Cumulative Index to Nursing and Allied Health Literature (CINAHL) databases were used. The search equation was “Palliative care and nursing care and emergency room”. A total of 12 studies were selected. Results: The studies agree on the need for training professionals in PC to provide a higher quality care, better identification of patient needs and to avoid unnecessary invasive processes. Similarly, the implementation of a collaborative model between ES and PC, the existence of a PC specialized team in the ES or proper palliative care at home correspond to a decrease in emergency visits, a lower number of hospitalizations or days admitted, and a decrease in hospital deaths. Conclusions: The development of PC in the di erent areas of patient care is necessary. Better palliative care leads to a lower frequency of ES by terminal patients, which has a positive impact on their quality of life. Access to PC from the emergency unit should be one of the priority health objectives due to increment in the aged population susceptible to this type of care.

In this paper, we describe our coronary stent (INC-1) design and development, the way that we found the specific characteristics needed for our device including biophysics aspects, design, finite element testing, manufacturing, and mechanic trials, we submitted and animal models experiences. The stent platform was cobalt-chromium L605 (Co-Cr), with struts thickness of 80 μm, balloon expandable. We placed the coronary stent INC-1 on a rabbit and dog models so we can evaluate efficacy and security of the device in relationship to its biomechanical properties including navigation capacity, traceability, symmetric expansion, and safety, as well as endothelial attachment, thrombogenicity, and lack of involvement of secondary branches in these models. We succeeded in efficacy and safety of the device after fluoroscopy-guided implant proving excellent capacity of release system, traceability, fluoroscopic visualization, symmetric expansion, and complete endothelial attach. Furthermore, we obtained a good post-implant balloon withdrawal, functional integrity, and no vascular complications. We observed adequate clinical evolution 3 weeks after the stent implantation.En esta publicación se describen el diseño y el desarrollo de un stent coronario (INC-1), la forma en que se determinaron las características biofísicas deseadas, el diseño y las pruebas computacionales por elemento finito, su fabricación, así como las pruebas mecánicas a las que se sometió el prototipo y por último las primeras experiencias en modelos animales. La plataforma del stent desarrollado fue de cobalto y cromo L605 (Co-Cr), con struts de 80 μm de grosor, expandido por balón. La colocación del stent coronario INC-1 se realizó en un modelo de conejo y uno canino con el objetivo de evaluar el éxito técnico y de seguridad del stent en relación con las propiedades biomecánicas (capacidad de navegación, maniobrabilidad, expansión simétrica del stent) y de seguridad (fijación a la pared vascular y ausencia de compromiso de ramas secundarias y formación de trombos en el momento de la colocación del stent en el modelo animal). Se obtuvo éxito técnico y de seguridad del stent después del implante guiado por fluoroscopia, lo que demostró adecuada capacidad del sistema liberador, excelente maniobrabilidad, adecuada visualización fluoroscópica, expansión simétrica y fijación completa a la pared vascular, capacidad para retirar el balón desinflado después del implante, e integridad funcional y sin complicaciones vasculares. La evolución clínica fue favorable a tres semanas del seguimiento planeado.

espanolAntecedentes: el costo de realizar una intervencion coronaria percutanea es considerablemente alto tanto para el paciente como para los sistemas de salud, que han impulsado el desarrollo de tecnologia local para ayudar a cubrir la necesidad de estos dispositivos. Metodos: El stent de metal desnudo INC-01 fue desarrollado en el Instituto Nacional de Cardiologia de la Ciudad de Mexico y fue implantado por primera vez en modelos porcinos con exito tecnico en el 100% de los parametros evaluados. Presentacion de casos: Presentamos los tres primeros casos de pacientes con cardiopatia isquemica a los que se les implanto el stent de metal desnudo INC-01. La ecografia intracoronaria se realizo tras la implantacion del stent, mostrando todas las caracteristicas del exito del implante durante la evaluacion y el seguimiento clinico. Conclusiones: Se realizo angiografia y ecografia intracoronaria demostrando que el stent de metal desnudo INC-01 tiene caracteristicas fisicas, biologicas e histologicas similares a las encontradas en los stents metalicos comerciales. EnglishBackground: The cost of performing a percutaneous coronary intervention is considerably high for the patient as well as for health systems, which have promoted the development of local technology to help meet the need for these devices. Methods: The INC-01 bare-metal stent was developed at the National Institute of Cardiology in Mexico City and was first implanted on porcine models with technical success in 100% of the evaluated parameters. Presentation of Cases: We present the first three cases of patients with ischemic heart disease, to whom the INC-01 bare-metal stent was implanted. Intracoronary ul- trasonography was performed post-stent implantation, showing all the characteristics of implant success during evaluation and clinical follow-up. Conclusions: Angiography and intracoronary ultrasound were carried out demonstrating that the INC-01 bare-metal stent has physical, biological, and histological characteristics similar to those found in commercial metallic stents. (REV INVEST CLIN. 2020;72(1):32-6)

Background PCI is an expensive procedure in our population and it implies a huge cost for the institutions and National Health Service. Aim of the study The main objective was to evaluate the technical and biological success of two stents designed in Mexico. Methods Ten York pigs, 4–6 months of age, underwent implantation of the bare metal INC-01 (10 stents) and INC-02 (6 stents) coronary stent in addition to a conventional commercial stent (10 stents). Technical success was evaluated immediately with angiography and Intravascular Ultrasound IVUS, continued by a mean follow-up of 4 month and a final angiographic, IVUS and histological evaluation. Results Initial technical success, angiography and IVUS between the three stents were not significant. One stent presented restenosis in follow-up (commercial stent), but all other stents presented excellent clinical outcome, satisfactory angiographic and IVUS results. Inflammation, proliferation and endothelialization between the stents had no major differences in histological analysis in a mean of 4 months follow-up. Conclusions In this pig model, the INC 01 and INC 02 stents showed the same delivering technical success, angiographic and IVUS features, biological and histological response compared to commercial last generation stents.

The atherosclerotic process in coronary arteries begins with endothelial dysfunction and may provoke thrombotic total occlusion and myocardial infarction. In this state-of-the-art review, we discuss recent evidence of atheroslerosis, vulnerable plaque, and hemodynamic changes in the coronary tree, as well as the current techniques we implement in the catheterization lab to evaluate coronary stenosis. It is clear that atherosclerosis is a chronic inflammatory condition with several consequences in the coronary tree, however, we are able now to characterize the plaque and to select the appropriate treatment for many patients.

Fil: Caputo, Liliana Noemí. Universidad Nacional del Nordeste. Facultad de Ciencias Exactas y Naturales y Agrimensura; Argentina. Fil: Jorge, María Josefa. Universidad Nacional del Nordeste. Facultad de Ciencias Exactas y Naturales y Agrimensura; Argentina. Fil: Espinoza, Ricardo Ramón Fabián. Universidad Nacional del Nordeste. Facultad de Ciencias Exactas y Naturales y Agrimensura; Argentina. Fil: Porcel, Eduardo Adolfo. Universidad Nacional del Nordeste. Facultad de Ciencias Exactas y Naturales y Agrimensura; Argentina. Fil: Romero, José Luis. Universidad Nacional del Nordeste. Facultad de Ciencias Exactas y Naturales y Agrimensura; Argentina. El objetivo de este trabajo es presentar la técnica de análisis estadístico implicativo (ASI) y ejemplificar su uso mediante el análisis de un ítem de la prueba de diagnóstico tomada en 2013 a ingresantes a la Facultad de Ciencias Exactas y Naturales y Agrimensura de la Universidad Nacional del Nordeste (Argentina). Como resultado del análisis se obtuvieron algunas relaciones establecidas por los sujetos evaluados entre el conocimiento de ciertos números reales como elementos de - o de alguno de sus subconjuntos (N, Z, Q, R-Q) - y la representación correcta en la recta real de cuatro de ellos. La ausencia de algunas relaciones conceptuales esperadas (como por ejemplo entre el conocimiento del conjunto numérico al que pertenece un determinado número y su representación en la recta numérica) permite detectar aquellas relaciones conceptuales que no integran la red cognitiva de los sujetos evaluados, lo cual parece estar indicando la necesidad de prever y poner en práctica actividades de enseñanza que favorezcan el establecimiento de dichas relaciones.

Una de cada 2000 personas en Europa tiene lesión medular (LM), es normalmente más sedentaria que el resto de la población y encuentra diferentes problemas para practicar ejercicio físico (EF), destacando la escasa formación específica de los profesionales del deporte. Con el objetivo de aportar información sobre la LM y su interacción con la práctica deportiva, se realizó una revisión de literatura científica que analiza sus alteraciones músculoesqueléticas, cardiovasculares, respiratorias, de termorregulación, genitourinarias e intestinales, las úlceras por presión, la disreflexia autonómica y los aspectos nutricionales, generando recomendaciones prácticas. Como conclusión, la práctica habitual de EF reduce la incidencia de enfermedades respiratorias y cardiovasculares, mejorando la condición física, la autonomía personal y la salud de las personas con LM, así como su calidad y esperanza de vida, pero es imprescindible conocer sus características particulares tanto para optimizar su rendimiento deportivo como para evitar graves complicaciones médicas.

El trabajo tuvo como objetivo Analizar la Praxis Pedagógica que realizan los docentes en la Universidad Politécnica Territorial de Yaracuy “Arístides Bastidas” (UPTYAB), Venezuela, en términos de lo establecido para el modelo de producción contemplado en el Primer Plan Socialista Desarrollo Económico y Social de la Nación (PPSDESN) 2007-2013 y el Segundo Plan Socialista de Desarrollo Económico y Social de la Nación (SPSDESN) 2013-2019, el tipo de investigación es analítica apoyada en un diseño no experimental, observacional, descriptivo de campo, la muestra la conformaron 27 docentes y 236 estudiantes pertenecientes a los cuatro primeros PNF que se implementaron en la UPTYAB, el análisis de la información se realizó usando la estadística no paramétrica a través del análisis univariado y el de ACPC para un P< 0,05 obteniendo como resultado que la praxis pedagógica que realizan los docentes sometidos a este estudio, se desarrolla entre los estilos de enseñanza tradicional constructivista–humanista, por lo que se concluye que además de estos estilos de enseñanza, se ha de requerir en la praxis docente, de la didáctica crítica como práctica de la investigación, para alcanzar en mayor medida los objetivos establecidos para el modelo de producción social contemplado en los PDESN 2007- 2013 y 2013- 2017.

During a study of a colour-marked population of Lesser Spotted Woodpecker (LSW) in NE Spain we found two cases of cooperative breeding, in which two females and a male were rearing the brood. One of the females was involved in both cooperative breeding cases, in two consecutive years. We analysed the feeding contribution of each individual to nestling care as well as feeding rates to nestlings. In both cases the male showed a (compensatory) reduction in nestling feeding due to the involvement of the second female. Total feeding rate increased slightly compared to regular (noncooperative) monogamous pairs. The high breeding success found in the second case (six eggs/six nestlings) is thought to be due to the cooperation of the three adults in nestling care. The two cooperative breeding cases were found in territories that suffered from significant selective logging of dead trees. This logging is thought to be a possible anthropogenic example of the ecological constraints hypothesis and a significant factor that could force atypical cooperative breeding attempts. A locally biased sex-ratio might result in the cooperation of two females and a male in both cases. No evidence of kinship was found among members of the cooperative breeding teams. We could not determine whether the cooperative breeding cases were monogamous or polygamous.

The study of endothelial dysfunction by positron emission tomography (PET) allows a non-invasive evaluation of the endotheliums role in the maintenance of tone and vascular homeostasis, thus the determination of regional myocardial flow, myocardial flow reserve, endothelium dependent vasodilatory index and inflammation level in the vascular wall in atherosclerosis and autoimmune diseases. Endothelial dysfunction results in significantly impaired physiological responses that often lead to the development of coronary atherosclerosis and coronary artery disease (CAD). PET allows the early recognition of endothelial dysfunction in order to evaluate a possible and beneficial response to medical interventions in the atherosclerosis process. This can help to establish a prognosis based in the early detection of patients at risk of CAD and offers the opportunity for early treatment. This article reviews the current knowledge regarding a non-invasive assessment for endothelial dysfunction and proposes the potential use of this promising technique for early detection of this prognostic marker in the coronary atherosclerotic process.