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Der CO2-Laser wird zur Anwendung bei rekonstruktiven Operationen vorgestellt. An cornua uteri und Harnblasen von Kaninchen wurden Exzisionen vorgenommen. Die freien Wundrander wurden adaptiert und laserkoaguliert. Nach diesen Eingriffen blieben 70% (Uterus) bzw. 90% (Harnblase) der Organe voll funktionsfahig.

For 230 patients with common epithelial ovarian cancer, the prognostic impact of age was examined. Statistical analysis was done using proportional hazard models, 3- and 5-year survival rates and median survival of stratified groups, and the Kaplan-Meier mean. Taking the age-adjusted mortality into account, the prognosis of the older patients was significantly worse. This effect depended primarily on early mortality (survival time less than 2 months). A comparative analysis was made of the prognostic factors age, grade, and stage, taking into account the correlation between factors. This analysis showed that, for our series, age was of lesser prognostic significance than grading, and both of these were of much less prognostic importance than staging.

Rabbit oocyte maturation was induced by i.v. injection of 100 mU/HCG. Six hours later the animals were sacrificed, their granulosa cells cultured 7-10 days and their oocytes incubated in different media for 5-6 h. The oocytes were then examined microscopically. The appearance of a polar body was taken as an indication that maturation had progressed. The results presented show that maturation of rabbit oocytes can be inhibited by granulosa cells in vitro (OMI = oocyte maturation inhibitor), the activity of OMI is influenced by gonadotrophins and cumulus cells have a facilitatory effect on OMI. The results give the first indication that OMI exists in rabbits and may contribute to the discussion about the existence of OMI in other species (e.g. the pig).

Die einmalige intramuskulare Gabe von 500 μg Sulproston 8–10 Std vor Vakuumaspiration oder Kurettage ermoglicht eine einfache, schonende, risikoarme und die Patientin wenig belastende Interruptio im I. Trimenon.