1. Ethyl 2-[1-(4-chlorophenyl)-2,5-dioxo-1,2,3,5-tetrahydroimidazo[1′,2′:1,2]pyrimidino[5,4-b][1]benzofuran-3-yl]acetate
- Author
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Zheng-Rong Zhu, Yu-Lu Chen, and Yang-Gen Hu
- Subjects
biology ,Pyrimidine ,General Chemistry ,Crystal structure ,Condensed Matter Physics ,biology.organism_classification ,Ring (chemistry) ,Organic Papers ,Medicinal chemistry ,chemistry.chemical_compound ,chemistry ,Side chain ,Tetra ,Molecule ,General Materials Science ,Ethyl group ,Methyl group - Abstract
The asymmetric unit of the title compound, C(22)H(16)ClN(3)O(5), consists of two crystallographically independent mol-ecules. The fused rings of the imidazo[1,2-a]benzo[4,5]furo[3,2-d]pyrimidine system are nearly coplanar and the chlorophenyl rings are twisted with respect to the two pyrimidinone ring systems by 71.00 (2) and 62.59 (2)°. The C atoms of the ethyl side chain are disordered and were refined using a split model. In the crystal structure, the mol-ecules are connected via weak intra- and inter-molecular C-H⋯O inter-actions are present. The ethyl group in one molecule is disordered over two positions, with site occupancy factors 0.55 and 0.45; in the other molecule only the methyl group is disordered over two positions, with site occupancy factors 0.6 and 0.4.
- Published
- 2007
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