1. [Gastroparesis may be the cause of unexplained dyspepsia in patients with primary Sjögren syndrome].
- Author
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Geyl S, Jacques J, Parreau S, Cypierre A, Tabouret T, Gondran G, Ly KH, Liozon E, Lapébie FX, Bezanahary H, Palat S, Monteil J, Loustaud-Ratti V, and Fauchais AL
- Subjects
- Adult, Aged, Delayed Diagnosis, Dyspepsia diagnosis, Dyspepsia epidemiology, Dyspepsia therapy, Female, Gastroparesis diagnosis, Gastroparesis epidemiology, Gastroparesis therapy, Humans, Middle Aged, Radionuclide Imaging, Retrospective Studies, Sjogren's Syndrome epidemiology, Sjogren's Syndrome therapy, Dyspepsia etiology, Gastroparesis complications, Sjogren's Syndrome complications
- Abstract
Introduction: Upper digestive symptoms may be present in up to 50% of patients with primary Sjögren syndrome (pSS). We report a retrospective cohort of gastroparesis in a population of pSS presenting unexplained dyspepsia. Delayed gastric emptying was defined by a gastric emptying time above 113min or by a retention percentage at 4h more than 10% on scintigraphy., Results: Eleven patients with primary Sjögren syndrome and gastroparesis were included in a retrospective study. Every patients were women of age 48±18y. The average time of gastric emptying was 725,18±704,45min. 64% of patients had abdominal pain or gastric heaviness. A central or peripheral neurologic involvement was described in respectively 9 and 27% of cases. The diagnostic delay of gastroparesis was higher than 24 months., Conclusion: In primary Sjögren syndrome, gastroparesis should be suspected in case of unexplained dyspepsia, and a scintigraphy performed to prove the diagnosis. A neurologic involvement could explain gastroparesis, but prospective studies are needed for a better understanding of this disorder., (Copyright © 2018 Société Nationale Française de Médecine Interne (SNFMI). Published by Elsevier SAS. All rights reserved.)
- Published
- 2018
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