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5 results on '"Stephan Wildi"'

1. COLOR: A Randomized Clinical Trial Comparing Laparoscopic and Open Resection for Colon Cancer

Author

Stephan Wildi, H. Lippert, Hajime Maeta, Takashi Maeba, Shinichi Yachida, Luis Ortiz de Zárate, Thomas Kotsis, Levent Tezcan, Sadık Perek, Kimberley Giffard, K. Thon, Emre F. Yekebas, Javier Osorio, Ahmet Batkin, H. Stöltzing, Sasan Najibi, V. Zolota, Ola Røkke, V. Patrinou, Haldun Uluutku, Shawn M. Garber, Hisao Wakabayashi, Matthew G. Cohen, Esperanza Bachs, Mehmet Levhi Akin, Joseph Espat, Jean-Jacques Tuech, Núria Farreras, Moshe Schein, Asiye Perek, Metin Kapan, Sukru Yildirim, M.R.B. Keighley, Idunn Nesvik, Peter Lehocky, Agathi Paphiti, T. Manger, Nib Soehendra, Jean-Pierre Arnaud, Xavier Rogiers, G. Skroubis, Dionysios Voros, Christoph Busch, Bernhard Egger, Ronald S. Chamberlain, Charles Sklar, Jason P. Shaw, Leslie H. Blumgart, Cengiz Erenoglu, Julie Miller, Olof Winzer, C. Vagianos, Jonathan S. Zager, Michael G. Sarr, Elias Mallas, M. Pross, Stefan W. Schmid, Markus Naef, C. Haeckel, Eric R. Frykberg, Ian K. Komenaka, Ertuğrul Göksoy, Karl Søndenaa, Jules E. Garbus, Jakob R. Izbicki, A. Buttafuoco, Patrick Pessaux, Markus W. Büchler, and Matrona Frangou

Subjects
Male, Laparoscopic surgery, medicine.medical_specialty, Colorectal cancer, medicine.medical_treatment, Malignancy, law.invention, Randomized controlled trial, Colon, Sigmoid, law, Open Resection, medicine, Humans, Laparoscopic resection, Prospective Studies, Laparoscopy, Colectomy, Aged, medicine.diagnostic_test, business.industry, fungi, Gastroenterology, food and beverages, Cancer, medicine.disease, Surgery, Europe, Sigmoid Neoplasms, Colonic Neoplasms, Female, business
Abstract

Background: Laparoscopic surgery has proven to be safe and effective. However, the value of laparoscopic resection for malignancy in terms of cancer outcome can only be assessed by large prospective randomized clinical trials with sufficient follow-up. Methods: COLOR (COlon carcinoma Laparoscopic or Open Resection) is a European multicenter randomized trial which has started in September 1997. In 24 hospitals in Sweden, The Netherlands, Germany, France, Italy and Spain, 1,200 patients will be included. The primary end point of the study is cancer-free survival after 3 years. Results: Within Conclusions: Although laparoscopic surgery appears of value in colorectal malignancy, results of randomized trials have to be awaited to determine the definitive place of laparoscopy in colorectal cancer. Considering the current accrual rate, the COLOR study will be completed in 2002.

Published
2000
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2. Efficacy and Safety of Weight-Adapted Nadroparin Calcium vs. Heparin Sodium in Prevention of Clinically Evident Thromboembolic Complications in 1,190 General Surgical Patients

Author

Stephan Wildi, Markus Naef, Markus W. Büchler, Bernhard Egger, and Stefan W. Schmid

Subjects
Male, medicine.medical_specialty, medicine.drug_class, Treatment outcome, Low molecular weight heparin, law.invention, Randomized controlled trial, law, medicine, Humans, Digestive System Surgical Procedures, Venous Thrombosis, Heparin, business.industry, Heparin sodium, Gastroenterology, Anticoagulants, Nadroparin, Middle Aged, Nadroparin calcium, medicine.disease, Surgery, Pulmonary embolism, Clinical trial, Treatment Outcome, Anesthesia, Female, Pulmonary Embolism, business, Surgical patients, medicine.drug
Abstract

Aims: In a prospective, randomized, single, general surgery center trial, comparison of the safety and efficacy of two low molecular weight heparin (LMWH; anti-Xa heparin sodium and weight-adapted nadroparin calcium) regimens was made. Patients and Methods: Eleven hundred and ninety patients undergoing various elective and emergency operations were randomized to receive daily either a fixed dose of 3,000 IU anti-Xa heparin sodium or a variable body weight-dependent dose of nadroparin calcium (weight 100 kg, 6,150 UI) once until discharge. The first injection was administered 2.5–6 h before elective and emergency operations, respectively. Patients with clinical suspicion of deep venous thrombosis (DVT) underwent phlebography. Patients with signs of pulmonary embolism (PE) were further investigated by a ventilation-perfusion scan. Results: Statistically, there were no significant differences in the incidence of clinically evident DVT, PE or LMWH-related complications between both prophylactic regimens. Only 4 of the total of 15 hemorrhagic complications (4 wound hematomas in the nadroparin calcium group) were not classified as clearly surgically related, Two DVTs were confirmed by phlebography (both in the nadroparin calcium group). PE was confirmed by ventilation-perfusion scans (1 fatal, 1 on autopsy) in 1 patient with heparin sodium and in 6 patients with nadroparin calcium. Conclusions: Both regimens were equally safe and the risk of clinically evident DVT and PE was similar.

Published
2000
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3. Subject Index Vol. 17, 2000

Author

Ertuğrul Göksoy, Jonathan S. Zager, Kimberley Giffard, Emre F. Yekebas, H. Stöltzing, Christoph Busch, Hajime Maeta, Takashi Maeba, Sukru Yildirim, Ronald S. Chamberlain, Dionysios Voros, Stephan Wildi, Haldun Uluutku, Agathi Paphiti, Xavier Rogiers, Núria Farreras, Stefan W. Schmid, G. Skroubis, Michael G. Sarr, V. Zolota, Luis Ortiz de Zárate, Jakob R. Izbicki, H. Lippert, Thomas Kotsis, Ola Røkke, Nib Soehendra, Markus W. Büchler, C. Vagianos, Metin Kapan, Karl Søndenaa, A. Buttafuoco, T. Manger, Mehmet Levhi Akin, Markus Naef, Jules E. Garbus, Matrona Frangou, Shawn M. Garber, Eric R. Frykberg, Charles Sklar, Jean-Pierre Arnaud, Hisao Wakabayashi, Patrick Pessaux, Sasan Najibi, Moshe Schein, Leslie H. Blumgart, Elias Mallas, Jean-Jacques Tuech, Peter Lehocky, M. Pross, Esperanza Bachs, Matthew G. Cohen, Jason P. Shaw, Cengiz Erenoglu, Julie Miller, Olof Winzer, Shinichi Yachida, Joseph Espat, Sadık Perek, Asiye Perek, Idunn Nesvik, K. Thon, Ahmet Batkin, Levent Tezcan, M.R.B. Keighley, Javier Osorio, Bernhard Egger, V. Patrinou, C. Haeckel, and Ian K. Komenaka

Subjects
medicine.medical_specialty, Index (economics), business.industry, Gastroenterology, Physical therapy, medicine, Physiology, Surgery, Subject (documents), business
Published
2000
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4. Contents Vol. 17, 2000

Author

Jakob R. Izbicki, Levent Tezcan, Joseph Espat, Stefan W. Schmid, Núria Farreras, Karl Søndenaa, M.R.B. Keighley, Javier Osorio, Jules E. Garbus, Shinichi Yachida, Asiye Perek, Idunn Nesvik, Nib Soehendra, Ronald S. Chamberlain, Bernhard Egger, T. Manger, K. Thon, Sasan Najibi, Sadık Perek, Ahmet Batkin, Mehmet Levhi Akin, Charles Sklar, Matthew G. Cohen, C. Vagianos, Markus W. Büchler, Cengiz Erenoglu, Leslie H. Blumgart, Julie Miller, Markus Naef, Stephan Wildi, Olof Winzer, Matrona Frangou, Eric R. Frykberg, Elias Mallas, M. Pross, V. Patrinou, Jason P. Shaw, C. Haeckel, V. Zolota, Luis Ortiz de Zárate, Thomas Kotsis, Ian K. Komenaka, Xavier Rogiers, G. Skroubis, Hajime Maeta, Takashi Maeba, Hisao Wakabayashi, Haldun Uluutku, Ola Røkke, Shawn M. Garber, Moshe Schein, Jean-Jacques Tuech, Peter Lehocky, Sukru Yildirim, Agathi Paphiti, H. Lippert, Esperanza Bachs, Patrick Pessaux, Jean-Pierre Arnaud, Michael G. Sarr, A. Buttafuoco, Ertuğrul Göksoy, Kimberley Giffard, Emre F. Yekebas, H. Stöltzing, Christoph Busch, Metin Kapan, Jonathan S. Zager, and Dionysios Voros

Subjects
Traditional medicine, business.industry, Gastroenterology, Medicine, Surgery, business
Published
2000
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