30 results on '"Enrique Pérez-Cuadrado Martínez"'
Search Results
2. Arrival in port
- Author
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Enrique Pérez-Cuadrado Martínez
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Docking (animal) ,Spanish language ,business.industry ,Spain ,Gastroenterology ,Library science ,Medicine ,Humans ,General Medicine ,business ,Port (computer networking) ,Language - Abstract
The Revista Espanola de Enfermedades Digestivas (REED), the flagship journal for gastroenterology in the Spanish language, is now docking at a new port where this editor-in-chief (EiC), who began his trek in 2015, will now go ashore.
- Published
- 2021
3. Small Bowel Enteroscopy − A Joint Clinical Guideline from the Spanish and Portuguese Small Bowel Study Groups
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Pedro Figueiredo, Sandra Lopes, Miguel Mascarenhas Saraiva, Pedro Alonso, Rolando Pinho, Óscar Nogales, Consuelo Gálvez, Bruno Rosa, Pilar Borque Barrera, Begoña González, Enrique Pérez-Cuadrado-Martínez, Patrícia Andrade, Francisco Sánchez Ceballos, Cristina Carretero, Enrique Pérez-Cuadrado-Robles, Carlos Bernardes, Pilar Esteban Delgado, Hélder Cardoso, Eduardo Valdivieso-Cortazar, Mileidis San-Juan-Acosta, Ana Ponte, César Prieto-Frías, Nuno Almeida, Javier García Lledó, Juan Egea-Valenzuela, Noemí Caballero, Federico Argüelles-Arias, Blas J. Gomez-Rodriguez, Susana Mão de Ferro, José Francisco Juanmartiñena-Fernández, and Cristina Chagas
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Enteroscopy ,Study groups ,medicine.medical_specialty ,Angioectasia ,enteroscopy ,capsule endoscopy ,device-assisted enteroscopy ,Guidelines ,03 medical and health sciences ,0302 clinical medicine ,angioectasia ,small bowel ,Medicine ,Medical physics ,Capsule endoscopy ,lcsh:RC799-869 ,General Environmental Science ,business.industry ,Gastroenterology ,Guideline ,language.human_language ,3. Good health ,Management algorithm ,030220 oncology & carcinogenesis ,language ,General Earth and Planetary Sciences ,030211 gastroenterology & hepatology ,Device-assisted enteroscopy ,lcsh:Diseases of the digestive system. Gastroenterology ,Portuguese ,business ,Small bowel, Enteroscopy - Abstract
The present evidence-based guidelines are focused on the use of device-assisted enteroscopy in the management of small-bowel diseases. A panel of experts selected by the Spanish and Portuguese small bowel study groups reviewed the available evidence focusing on the main indications of this technique, its role in the management algorithm of each indication and on its diagnostic and therapeutic yields. A set of recommendations were issued accordingly.Estas recomendações baseadas na evidência detalham o uso da enteroscopia assistida por dispositivo no manejo clínico das doenças do intestino delgado. Um conjunto de Gastrenterologistas diferenciados em patologia do intestino delgado foi selecionado pelos grupos de estudos Espanhol e Portugués de intestino delgado para rever a evidência disponível sobre as principais indicações desta técnica, o seu papel nos algoritmos de manejo de cada indicação e sobre o seu rendimento diagnóstico e terapêutico. Foi gerado um conjunto de recomendações pelos autores.
- Published
- 2020
4. Retrograde enteroclysis by double balloon enteroscopy in a patient with blunt abdominal trauma: small bowel stricture, intraluminal vascular lesion and Crohn's disease
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Alejandro Pérez Fernández, Gloria Palomares Ortiz, and Enrique Pérez-Cuadrado Martínez
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Adult ,Male ,medicine.medical_specialty ,Abdominal pain ,Abdominal Injuries ,Constriction, Pathologic ,Wounds, Nonpenetrating ,Pseudoaneurysm ,Blunt ,Crohn Disease ,Double-balloon enteroscopy ,medicine ,Humans ,Double-Balloon Enteroscopy ,Crohn's disease ,medicine.diagnostic_test ,business.industry ,Gastroenterology ,General Medicine ,Emergency department ,medicine.disease ,Abdominal trauma ,Angiography ,Radiology ,medicine.symptom ,business - Abstract
A 40-year-old male presented to the Emergency Department after a driving accident with blunt abdominal trauma. An abdominal computed tomography (CT) scan revealed a mesenteric injury in the right lower quadrant. He was admitted two months later due to a one-day history of abdominal pain and diarrhea, without fever or blood. The CT angiography showed a pseudoaneurysm located in the proximal ileum and several rigid small bowel (SB) loops with segmental wall thickening of mucosa.
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- 2020
5. Recurrent small-bowel bleeding from a Dieulafoy�s lesion after combined endoscopic treatment
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María Josefa Sánchez Fernández, José Manuel Molina Muñoz, Enrique Pérez-Cuadrado Martínez, José Luis Rodrigo Agudo, Silvia Chacón Martínez, José María Rubio Mateos, Enrique Pérez-Cuadrado Robles, Pilar Esteban Delgado, and Alejandro Pérez Fernández
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Gynecology ,medicine.medical_specialty ,business.industry ,Gastroenterology ,General Medicine ,Dieulafoy's lesion ,medicine.disease ,Capsule Endoscopy ,Combined Modality Therapy ,Intestine, Small ,Humans ,Medicine ,Gastrointestinal Hemorrhage ,business ,Endoscopic treatment ,Retrospective Studies - Abstract
Introduccion: la lesion de Dieulafoy en intestino delgado es una causa infrecuente de hemorragia digestiva que recidiva frecuentemente tras su tratamiento endoscopico. Material y metodos: se presenta un estudio observacional, descriptivo, retrospectivo y unicentrico de 15 pacientes con hemorragia de intestino delgado, diagnosticados de lesion de Dieulafoy con capsula endoscopica o enteroscopia doble balon, en los que se realizo tratamiento endoscopico combinado. Resultados y conclusiones: durante una mediana de seguimiento de 33,5 meses (rango 2-145), recidivaron tres de los 12 casos que se pudieron seguir (25 %) y todos ocurrieron precozmente en las primeras 48 horas tras la terapeutica. Se retrataron con exito dos de ellos con una nueva enteroscopia.
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- 2020
6. COVID-19 and the digestive system: protection and management during the SARS-CoV-2 pandemic
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Enrique Pérez-Cuadrado Martínez, Javier Crespo, Joaquín Hinojosa del Val, Federico García, Javier Ampuero, Julio Iglesias-Garcia, Ángel Gil de Miguel, and Carlos Fernández Carrillo
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medicine.medical_specialty ,Coronavirus disease 2019 (COVID-19) ,medicine.medical_treatment ,Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ,Digestive System Diseases ,Pneumonia, Viral ,Liver transplantation ,03 medical and health sciences ,Betacoronavirus ,0302 clinical medicine ,Internal medicine ,Pandemic ,medicine ,Disease Transmission, Infectious ,Infection control ,Humans ,Endoscopy, Digestive System ,skin and connective tissue diseases ,Intensive care medicine ,Pandemics ,Infection Control ,business.industry ,Transmission (medicine) ,SARS-CoV-2 ,Gastroenterology ,COVID-19 ,General Medicine ,Hepatology ,medicine.disease ,Liver Transplantation ,Pneumonia ,030220 oncology & carcinogenesis ,030211 gastroenterology & hepatology ,business ,Coronavirus Infections ,Digestive System ,Immunosuppressive Agents - Abstract
The purpose of this rapid review is to provide an update on the impact of SARS-CoV-2 infection on Gastroenterology and Hepatology departments, our patients, and our new way of working. The gastrointestinal tract and the liver are affected by SARS-CoV-2, especially in patients with immunosuppressive therapies. Patients with liver transplantation should be followed closely. Digestive endoscopy is a high-risk procedure for the transmission of SARS-CoV-2. While the pandemic lasts, we must adapt its indications and promote protective measures for patients and healthcare professionals alike. The COVID-19 pandemic has changed our priorities and the way we work, although we do not know what the repercussions will be after normality is reinstated.
- Published
- 2020
7. Does it matter how long the small bowel is?
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Enrique Pérez-Cuadrado Martínez
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Double-Balloon Enteroscopy ,Enteroscopy ,medicine.medical_specialty ,medicine.diagnostic_test ,business.industry ,Gastroenterology ,General Medicine ,Gold standard (test) ,Diagnostic strategy ,Capsule Endoscopy ,Endoscopy, Gastrointestinal ,Endoscopy ,law.invention ,Single-Balloon Enteroscopy ,Capsule endoscopy ,law ,Intestine, Small ,medicine ,Humans ,Laparoscopy ,Radiology ,Intraoperative enteroscopy ,business - Abstract
The small bowell (SB) is a very long organ hardly accessible to conventional endoscopy. The revolution entailed by its complete diagnostic exploration with capsule endoscopy (CE) has led to a change in traditional surgical management and its related gold standard - intraoperative enteroscopy. CE is currently the first-line diagnostic strategy for the SB. An emergent technique in its wake has played a key role in the management of patients with SB conditions: to wit, device-assisted enteroscopy (DAE). Thus were developed first double-balloon enteroscopy (DBE), then single-balloon enteroscopy, and most recently motorized spiral enteroscopy.
- Published
- 2020
8. Advanced therapy by device-assisted enteroscopy
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Enrique Pérez-Cuadrado Robles and Enrique Pérez-Cuadrado Martínez
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Double-Balloon Enteroscopy ,Enteroscopy ,medicine.medical_specialty ,Percutaneous ,medicine.diagnostic_test ,business.industry ,medicine.medical_treatment ,Jejunostomy ,Gastroenterology ,Endoscopic mucosal resection ,General Medicine ,medicine.disease ,Endoscopy, Gastrointestinal ,Polypectomy ,Endoscopy ,Double-balloon enteroscopy ,Intestine, Small ,medicine ,Humans ,Radiology ,Foreign body ,Gastrointestinal Hemorrhage ,business - Abstract
Standard therapy using device-assisted enteroscopy includes different hemostatic therapies, polypectomy, dilation and other possibilities. The most frequent indication is small bowel bleeding. However, other specific settings could require dedicated therapies such as desinvagination, percutaneous enteroscopic jejunostomy, stent placement, endoscopic mucosal resection in polypoid vascular lesions and foreign body extraction. The present review aimed to investigate and describe device-assisted advanced therapies in the small bowel, excluding conventional hemostatic therapies of vascular lesions.
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- 2020
9. Small but great steps
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Enrique Pérez-Cuadrado Martínez and Javier A. Cienfuegos
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Enthusiasm ,business.industry ,media_common.quotation_subject ,Digestive System Diseases ,Gastroenterology ,General Medicine ,Rigour ,Pleasure ,Task (project management) ,Spain ,Medicine ,Humans ,Engineering ethics ,Quality (business) ,Journal Impact Factor ,Periodicals as Topic ,business ,GeneralLiterature_REFERENCE(e.g.,dictionaries,encyclopedias,glossaries) ,Editorial Policies ,media_common - Abstract
At the beginning of 2020 it is our pleasure to inform our readers about the changes in structure and future projects this journal will undertake. First of all, we wish to thank The National and International Editorial Committee, as well as the journal reviewers, for their enthusiasm, dedication, and scientific rigor in their silent and behind-the-scenes task of improving the quality of the published materials.
- Published
- 2019
10. Indicaciones y rendimiento diagnóstico de la cápsula endoscópica en el anciano
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Enrique Pérez-Cuadrado-Martínez, L.E. Zamora-Nava, Enrique Pérez-Cuadrado-Robles, and Victoria Alejandra Jiménez-García
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03 medical and health sciences ,0302 clinical medicine ,030220 oncology & carcinogenesis ,Gastroenterology ,lcsh:Diseases of the digestive system. Gastroenterology ,030211 gastroenterology & hepatology ,lcsh:RC799-869 - Abstract
Resumen: Introducción y Objetivos: La creciente población anciana y el uso amplio de la endoscopia por cápsula han llevado a una cantidad mayor de procedimientos en aquellos pacientes. El objetivo del presente estudio fue valorar la utilidad de la endoscopia por cápsula en pacientes mayores. Materiales y Métodos: Se clasificó a todos los pacientes consecutivos en nuestro centro sometidos a cápsula endoscópica (CE) dentro del periodo de tiempo 2004-2016 como mayores (≥75 años) y más jóvenes. Los hallazgos y el rendimiento de diagnóstico se valoraron comparativamente. Resultados: De 2,311 pacientes (edad promedio: 59.5 ± 19.23 años, 44.48% hombres), 648 se encontraban en el grupo de mayores y 1,663 en el grupo de más jóvenes. El tiempo de tránsito gástrico fue más corto en los pacientes mayores (p=0.001), mientras que el tiempo de tránsito del intestino delgado fue más corto en el grupo de pacientes más jóvenes (p
- Published
- 2018
11. Indications for and diagnostic yield of capsule endoscopy in the elderly
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Victoria Alejandra Jiménez-García, L.E. Zamora-Nava, Enrique Pérez-Cuadrado-Robles, and Enrique Pérez-Cuadrado-Martínez
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Adult ,Male ,Aging ,Abdominal pain ,medicine.medical_specialty ,Malabsorption ,Gastrointestinal Diseases ,Sangrado gastrointestinal de origen oscuro ,Population ,Transit time ,Capsule Endoscopy ,Gastroenterology ,law.invention ,03 medical and health sciences ,Elderly ,0302 clinical medicine ,Older patients ,Capsule endoscopy ,law ,Internal medicine ,medicine ,Humans ,Prospective Studies ,Patient group ,Gastrointestinal Transit ,education ,Aged ,Aged, 80 and over ,education.field_of_study ,business.industry ,Pacientes mayores ,General Medicine ,Middle Aged ,Small bowel ,medicine.disease ,Obscure gastrointestinal bleeding ,030220 oncology & carcinogenesis ,Intestino delgado ,Female ,030211 gastroenterology & hepatology ,medicine.symptom ,Gastrointestinal Hemorrhage ,business ,Ancianos ,Endoscopia por cápsula - Abstract
Introduction And Aims The growing elderly population and wide use of capsule endoscopy have led to a higher number of procedures in those patients. The aim of the present study was to assess the usefulness of capsule endoscopy in older patients. Materials And Methods All consecutive patients undergoing capsule endoscopy at our center within the time frame of 2004-2016 were classified as older (≥75 years of age) and younger. Findings and diagnostic yield were comparatively assessed. Results Of 2311 patients (mean age: 59.5 ± 19.23 years, 44.48% male), 648 were in the older group and 1663 in the younger group. Gastric transit time was shorter in the older patients ( p=0.001 ), whereas small bowel transit time was shorter in the younger patients ( p ). Overall diagnostic yield in the elderly was higher (50.66% vs . 41.19%, p ). Obscure gastrointestinal bleeding was the most frequent indication for capsule endoscopy in the elderly (90.4% vs. 53.77%, p ), achieving a higher diagnostic yield than in the younger population (51.47% vs. 42.76%, p=0.002 ), whereas Crohn's disease, suspected or known neoplasms/polyps, malabsorption syndrome, and abdominal pain were the indications in the younger patient group. Such indications were rare in the older group. Vascular lesions and active bleeding were more frequently diagnosed in the older patients, whereas ulcers/erosions and mucosal atrophy were more common in the younger patients ( p ). Conclusions Capsule endoscopy achieved a higher overall diagnostic yield in the elderly patients. Obscure gastrointestinal bleeding indication for capsule endoscopy was much more frequent in the advanced-age group and had a higher diagnostic yield.
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- 2018
12. Conflict of interest. Why is it important?
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Enrique Pérez-Cuadrado Martínez and Javier A. Cienfuegos
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Publishing ,business.industry ,Conflict of Interest ,media_common.quotation_subject ,Gastroenterology ,Publishing ethics ,Conflict of interest ,MEDLINE ,General Medicine ,Public relations ,State (polity) ,Medicine ,business ,Reciprocal ,media_common - Abstract
Scientific publications are the main medium for distributing scientific contributions, be they original studies, reviews, clinical guidelines, editorials or consensus statements promoted by scientific societies, and they may be privately-, state- or industry-funded. The relationship between authors and sources of funding must be expressed transparently, truthfully and completely always ensuring a climate of reciprocal trust between journals and readers.
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- 2019
13. Lumboperitoneal shunt: a foreign body detected in the small bowel by capsule endoscopy
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José María Rubio Mateos, Enrique Pérez-Cuadrado Martínez, María Josefa Sánchez Fernández, Pilar Esteban Delgado, José Francisco Sánchez Melgarejo, Silvia Chacón Martínez, and Alejandro Pérez Fernández
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medicine.medical_specialty ,Catheters ,business.industry ,Gastroenterology ,Middle Aged ,medicine.disease ,Foreign Bodies ,Capsule Endoscopy ,Cerebrospinal Fluid Shunts ,Surgery ,law.invention ,Lumboperitoneal shunt ,Capsule endoscopy ,law ,Intestine, Small ,medicine ,Humans ,Female ,Foreign body ,business - Published
- 2019
14. Capsule endoscopy and deep enteroscopy
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Enrique Pérez-Cuadrado, Martínez, Enrique, Pérez-Cuadrado Martínez, Enrique Pérez-Cuadrado, Robles, and Enrique, Pérez-Cuadrado Robles
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Enteroscopy ,medicine.medical_specialty ,MEDLINE ,Capsule Endoscopy ,law.invention ,Video capsule endoscopy ,Crohn Disease ,Capsule endoscopy ,law ,Double-balloon enteroscopy ,Intestine, Small ,medicine ,Humans ,Radiology, Nuclear Medicine and imaging ,Double-Balloon Enteroscopy ,medicine.diagnostic_test ,business.industry ,General surgery ,Gastroenterology ,Computed tomography enterography ,Foreign Bodies ,Magnetic resonance enterography ,Endoscopy ,Radiology ,Gastrointestinal Hemorrhage ,business ,Intestinal Obstruction ,Obscure gastrointestinal bleeding - Abstract
During the 2014 Digestive Disease Week in Chicago, many high-quality studies on small-bowel endoscopy were presented. The most relevant abstracts from around the world of two complementary procedures – capsule endoscopy and deep enteroscopy – which have seen rapid changes in recent years, have been selected for this review.
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- 2014
15. The Role of Emergency Endoscopy in Small Bowel Bleeding: A Review
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Enrique Pérez-Cuadrado-Robles and Enrique Pérez-Cuadrado-Martínez
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Enteroscopy ,medicine.medical_specialty ,Gastrointestinal, Haemorrhage ,Review Article ,Endoscopy, Gastrointestinal ,law.invention ,03 medical and health sciences ,0302 clinical medicine ,Capsule endoscopy ,law ,Intestine, Small ,medicine ,lcsh:RC799-869 ,Intestino Delgado ,medicine.diagnostic_test ,business.industry ,General surgery ,Endoscopia Gastrointestinal ,Gastroenterology ,Interventional radiology ,Gastrointestinal haemorrhage ,Hemorragia Gastrointestinal ,Endoscopy ,Surgery ,030220 oncology & carcinogenesis ,lcsh:Diseases of the digestive system. Gastroenterology ,030211 gastroenterology & hepatology ,Narrative review ,business ,Obscure gastrointestinal bleeding - Abstract
There is no consensus on the timing and management of emergency overt obscure gastrointestinal bleeding. Emergency capsule endoscopy and balloon-assisted enteroscopy have a high diagnostic and therapeutic yield in these situations. Most lesions detected by small bowel endoscopy are amenable to endoscopic haemostasis, although some lesions still require surgery or interventional radiology. The management of these patients is varied, and doubt persists about which technique should be preferred as first-line treatment. This narrative review analyses the usefulness and impact of small bowel endoscopic techniques in the emergency setting for severe overt obscure gastrointestinal bleeding.Não existe consenso sobre a melhor estratégia e respetivos tempos na abordagem urgente da hemorragia digestiva obscura manifesta. A cápsula endoscópica e a enteroscopia assistida por balão de urgência têm elevada rentabilidade diagnóstica e terapêutica nesta indicação. A maioria das lesões detetadas na endoscopia do intestino delgado são passíveis de hemostase endoscópica, apesar de algumas ainda necessitarem de tratamento cirúrgico ou de técnicas de radiologia de intervenção. A abordagem destes pacientes é variada e persistem dúvidas sobre qual deverá ser a técnica de primeira linha. Este artigo de revisão analisa a utilidade e o impacto das técnicas endoscópicas do intestino delgado em contexto urgente na abordagem da hemorragia digestiva obscura manifesta severa.
- Published
- 2016
16. Intermediate‐risk patients with three to four small adenomas should be considered low risk for colorectal cancer screening
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Silvia Chacón-Martínez, Noé Quesada-Vázquez, Enrique Pérez-Cuadrado-Robles, Paloma Bebia-Conesa, Pilar Esteban-Delgado, José Luis Rodrigo-Agudo, Enrique Pérez-Cuadrado-Martínez, Emilio Torrella-Cortés, Francisco Pérez-Riquelme, and Aurelio López-Martín
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Adenoma ,Male ,medicine.medical_specialty ,Multivariate analysis ,Colonic Polyps ,Colonoscopy ,Gastroenterology ,Lesion ,03 medical and health sciences ,0302 clinical medicine ,Risk Factors ,Internal medicine ,medicine ,Humans ,Radiology, Nuclear Medicine and imaging ,Early Detection of Cancer ,Aged ,Invasive carcinoma ,medicine.diagnostic_test ,business.industry ,Middle Aged ,medicine.disease ,Colorectal cancer screening ,030220 oncology & carcinogenesis ,Female ,030211 gastroenterology & hepatology ,medicine.symptom ,Colorectal Neoplasms ,Intermediate risk ,business ,Follow-Up Studies ,Index Colonoscopy - Abstract
Background and Aim Intermediate-risk patients following a colorectal cancer screening program may have differential risk of advanced lesions depending on the findings of an index colonoscopy. The aim of the present study was to comparatively assess advanced colorectal neoplasia risk at the first follow-up colonoscopy among the different intermediate-risk subgroups with a focus on patients with three to four adenomas. Methods All patients recruited for a baseline screening colonoscopy between 2006 and 2011 were included. Number, size and histopathological characteristics of adenomas were collected. Main outcome was an advanced colorectal neoplasia detection rate (invasive carcinoma or advanced adenoma) at the first follow-up colonoscopy. Low- and high-risk patients were excluded. Results Five hundred and sixty-one intermediate-risk patients (63.3% men, mean age: 59.01 ± 6.16 years) underwent indexing and follow-up colonoscopy. By multivariate analysis, three to four adenomas (OR: 3.613 [95% CI: 1.661–7.859], P = 0.001) and adenoma size ≥10
- Published
- 2015
17. Achievements and objectives for 2019
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Enrique Pérez-Cuadrado Martínez and Javier A. Cienfuegos
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Medical education ,Web of science ,business.industry ,Gastroenterology ,MEDLINE ,General Medicine ,Editorial board ,03 medical and health sciences ,0302 clinical medicine ,Spain ,Medicine ,030211 gastroenterology & hepatology ,030212 general & internal medicine ,Periodicals as Topic ,Ultrasonography ,business ,Editorial Policies ,Gastrointestinal endoscopy - Abstract
At the beginning of 2019 we wish to inform our readers and share with them the achievements and objectives of the Editorial Board. With the gradual growth of the journal, and to be more efficient and better serve the scientific societies it represents (Spanish Society of Gastroenterology [SEPD], Spanish Society of Gastrointestinal Endoscopy [SEED] and Spanish Association of Digestive Ultrasonography [AEED]), we made the decision to progressively increase the number of papers per issue, and to adapt manuscript classification to the requirements of Web of Science. The number of original papers was increased to six, and we look forward to having a total of eight, with two clinical notes and two images in digestive disorders, and keeping one review and/or special article per issue.
- Published
- 2018
18. Guidelines for reviewers of The Spanish Journal of Gastroenterology (REED)
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Enrique Pérez-Cuadrado Martínez and Javier A. Cienfuegos
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Medical education ,business.industry ,Gastroenterology ,General Medicine ,03 medical and health sciences ,0302 clinical medicine ,Spain ,030220 oncology & carcinogenesis ,Medicine ,030211 gastroenterology & hepatology ,Periodicals as Topic ,business ,Editorial Policies - Abstract
The peer review continues to be the most widespread procedure in the evaluation of scientific papers. We present the evaluation criteria of original articles and the responsibilities of the reviewers regarding the authors and the Editor.
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- 2018
19. High short-term rebleeding rate in patients undergoing a second endoscopic therapy for small-bowel angioectasias after recurrent bleeding
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Rolando Pinho, Ana Ponte, Adélia Rodrigues, Pilar Esteban Delgado, Enrique Pérez-Cuadrado Martínez, Jaime Rodrigues, Enrique Pérez-Cuadrado Robles, Joana Silva, and João Carvalho
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Male ,Enteroscopy ,medicine.medical_specialty ,Gastrointestinal bleeding ,Blood transfusion ,medicine.medical_treatment ,Angioectasias ,Endoscopy, Gastrointestinal ,03 medical and health sciences ,Postoperative Complications ,0302 clinical medicine ,Recurrence ,Risk Factors ,Double-balloon enteroscopy ,Intestine, Small ,medicine ,Humans ,Device ,In patient ,lcsh:RC799-869 ,Aged ,Retrospective Studies ,Double-Balloon Enteroscopy ,medicine.diagnostic_test ,business.industry ,Gastroenterology ,Retrospective cohort study ,General Medicine ,Middle Aged ,Bleed ,medicine.disease ,Endoscopy ,Surgery ,Intestinal Diseases ,Treatment Outcome ,030220 oncology & carcinogenesis ,Female ,lcsh:Diseases of the digestive system. Gastroenterology ,030211 gastroenterology & hepatology ,assisted enteroscopy ,Gastrointestinal Hemorrhage ,business ,Small-bowel vascular lesions ,Dilatation, Pathologic - Abstract
Background: Angioectasias represents the most frequently found lesion in the small bowel by device-assisted enteroscopy for obscure gastrointestinal bleeding in Western countries. Recurrence of gastrointestinal bleeding after angioectasias therapy remains unclear and data regarding the efficacy of additional endoscopic therapeutic sessions to reduce the rebleeding rate is limited. Aim: To evaluate the rebleeding rate in small bowel angioectasias after a second endoscopic treatment with balloon-assisted enteroscopy after an initial bleed during the first endoscopic treatment. Methods: A retrospective double-center study of patients with small-bowel angioectasias undergoing a second enteroscopy treatment due to a first rebleeding episode. The endpoint was rebleeding, defined as the need for a blood transfusion, the presence of overt bleeding or a decrease in hemoglobin ≥ 2 g/dL. Results: Fifteen of 37 (40.5%) patients with small-bowel angioectasias that underwent a second endoscopic therapy after a first rebleeding episode (n = 15) experienced a second rebleeding episode. Kaplan-Meier curve analysis showed that most rebleeding episodes occurred within the first 12 months of follow-up, resulting in a rebleeding rate of 33.1% at 6 months, 39.1% at 12 months and 52.6% at 24 months. Conclusions: Despite the high absolute short-term rebleeding rate, further endoscopic treatments may be beneficial due to the effective reduction of rebleeding in a subset of patients.
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- 2018
20. On the centenary of The Spanish Journal of Gastroenterology (REED)
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Javier A. Cienfuegos and Enrique Pérez-Cuadrado Martínez
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medicine.medical_specialty ,business.industry ,Gastroenterology ,General Medicine ,History, 20th Century ,History, 21st Century ,03 medical and health sciences ,0302 clinical medicine ,Spain ,030220 oncology & carcinogenesis ,Internal medicine ,medicine ,030211 gastroenterology & hepatology ,The Internet ,Periodicals as Topic ,business ,GeneralLiterature_REFERENCE(e.g.,dictionaries,encyclopedias,glossaries) - Abstract
Editor-in Chief and Executive Editor summerize the recent evolution of The Spanish Journal of Gastroenterology. They tackle several questions regarding the internet impact on scientific journals.
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- 2018
21. Emergency double‐balloon enteroscopy combined with real‐time viewing of capsule endoscopy: <scp>A</scp> feasible combined approach in acute overt‐obscure gastrointestinal bleeding?
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Pilar Esteban Delgado, Rafael Latorre, Federico Soria, Blanca Martínez Andrés, Enrique Pérez-Cuadrado Robles, Enrique Pérez-Cuadrado Martínez, José Luis Rodrigo Agudo, Aurelio López Martín, Paloma Bebia Conesa, Antonio López Higueras, and Luis Eduardo Zamora Nava
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Male ,Enteroscopy ,medicine.medical_specialty ,Capsule Endoscopy ,Risk Assessment ,Severity of Illness Index ,law.invention ,Capsule endoscopy ,law ,Double-balloon enteroscopy ,Severity of illness ,medicine ,Humans ,Combined Modality Therapy ,Radiology, Nuclear Medicine and imaging ,Aged ,Retrospective Studies ,Aged, 80 and over ,Double-Balloon Enteroscopy ,medicine.diagnostic_test ,business.industry ,Gastroenterology ,Retrospective cohort study ,Middle Aged ,Dieulafoy's lesion ,medicine.disease ,Surgery ,Treatment Outcome ,Acute Disease ,Feasibility Studies ,Female ,Patient Safety ,Radiology ,Emergencies ,Gastrointestinal Hemorrhage ,business ,Follow-Up Studies ,Obscure gastrointestinal bleeding - Abstract
Background and Aim There are few data concerning emergency double-balloon enteroscopy (DBE) and its usefulness in the management of severe acute obscure gastrointestinal bleeding (OGIB). The aim of this retrospective study was to evaluate emergency DBE and capsule endoscopy (CE) in patients with overt OGIB, analyzing the feasibility of this combined approach. Methods Emergency DBE in patients with overt OGIB was defined as performance within 24 h of symptom onset. We reported 27 patients (16 men, mean age: 64.6 ± 17.9 years) with overt severe bleeding who underwent 29 emergency DBE (22 anterograde, 7 retrograde). Of 27 patients, 16 (59.3%) underwent CE with real time (RT) viewing. Results Patients were diagnosed with the following: Dieulafoy's lesion (DL; n = 11, 40.7%), angioectasia (n = 7, 25.9%), tumors (n = 4, 14.8%), diverticulum (n = 3, 11.1%), ulcers (n = 2, 7.4%). We diagnosed 23 lesions amenable to endoscopic hemostasis and successfully treated 21 of them (77.8%). DL detection rate was statistically higher in the emergency DBE group than in OGIB patients with DBE done 24 h after symptom onset (40.7% vs 0.9%, respectively, P
- Published
- 2014
22. Role of capsule endoscopy in alarm features and non-responsive celiac disease: A European multicenter study
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Cristina Carretero-Ribón, Juan-Manuel Herrerıas-Gutierrez, Juan Egea-Valenzuela, Javier Sempere-Garcia-Argüelles, Ignacio Fernandez-Urien-Sainz, Begoña González-Suárez, Antonio López-Higueras, Federico Argüelles-Arias, Javier Garcıa-Lledo, Vicente Pons-Beltrán, Enrique Pérez-Cuadrado-Robles, Enrique Pérez-Cuadrado-Martínez, Santiago Gonzalez-Vazquez, Mileidis San Juan-Acosta, Pilar Borque-Barrera, Federica Branchi, Marisol Luján-Sanchis, Jose-Francisco Juanmartinena-Fernandez, Victoria-Alejandra Jimenez-Garcıa, Francisco Sanchez-Ceballos, Lucıa Ruano-Dıaz, Bruno Rosa, Luca Elli, Noelia Alonso-Lázaro, Julio Valle-Muñoz, and Sofia Xavier
- Subjects
Adult ,Male ,medicine.medical_specialty ,Disease ,Gastroenterology ,Capsule Endoscopy ,Risk Assessment ,Severity of Illness Index ,law.invention ,Cohort Studies ,03 medical and health sciences ,Diet, Gluten-Free ,Young Adult ,0302 clinical medicine ,Intestinal mucosa ,Capsule endoscopy ,law ,Internal medicine ,Severity of illness ,Intestine, Small ,medicine ,Humans ,Radiology, Nuclear Medicine and imaging ,Young adult ,Intestinal Mucosa ,Retrospective Studies ,business.industry ,Retrospective cohort study ,Middle Aged ,medicine.disease ,Lymphoma ,Celiac Disease ,030220 oncology & carcinogenesis ,Disease Progression ,030211 gastroenterology & hepatology ,Female ,business ,Cohort study ,Follow-Up Studies - Abstract
Background and aim The role of capsule endoscopy (CE) in established celiac disease (CD) remains unclear. Our objective was to analyze the usefulness of CE in the suspicion of complicated CD. Methods This was a retrospective multicenter study. One hundred and eighty-nine celiac patients (mean age: 46.6 ± 16.6, 30.2% males) who underwent CE for alarm symptoms (n = 86, 45.5%) or non-responsive CD (n = 103, 54.5%) were included. Diagnostic yield (DY), therapeutic impact and safety were analyzed. Results Capsule endoscopy was completed in 95.2% of patients (small bowel transit time: 270.5 ± 100.2 min). Global DY was 67.2%, detecting atrophic mucosa (n = 92, 48.7%), ulcerative jejunoileitis (n = 21, 11.1%), intestinal lymphoma (n = 7, 3.7%) and other enteropathies (n = 7, 3.7%, six Crohn's disease cases and one neuroendocrine tumor). The DY of CE was significantly higher in patients presenting with non-responsive disease compared to patients with alarm symptoms (73.8% vs 59.3%, P = 0.035). The new findings of the CE modified management in 59.3% of the cases. There were no major complications. Conclusion Capsule endoscopy may be a moderately helpful and safe diagnostic tool in the suspicion of complicated CD, modifying the clinical course of these patients.
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- 2017
23. Short article: Capsule endoscopy in graft-versus-host disease
- Author
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L Quénéhervé, Antonio López-Higueras, Enrique Pérez-Cuadrado-Robles, Enrique Pérez-Cuadrado-Martínez, and Cristina Castilla-Llorente
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Adult ,Male ,medicine.medical_specialty ,Gastrointestinal Diseases ,medicine.medical_treatment ,Graft vs Host Disease ,Hematopoietic stem cell transplantation ,Gastroenterology ,Capsule Endoscopy ,Sensitivity and Specificity ,Severity of Illness Index ,law.invention ,03 medical and health sciences ,0302 clinical medicine ,Capsule endoscopy ,law ,Predictive Value of Tests ,Internal medicine ,medicine ,Humans ,Aged ,Retrospective Studies ,Hepatology ,medicine.diagnostic_test ,business.industry ,Hematopoietic Stem Cell Transplantation ,Retrospective cohort study ,Gold standard (test) ,Middle Aged ,medicine.disease ,Endoscopy ,Surgery ,surgical procedures, operative ,Graft-versus-host disease ,030228 respiratory system ,Predictive value of tests ,030211 gastroenterology & hepatology ,Female ,business - Abstract
The gold standard in the diagnosis of gastrointestinal graft-versus-host disease (GVHD) after allogenic hematopoietic stem cell transplantation is conventional endoscopy with histopathological assessment. The role of capsule endoscopy (CE) is uncertain. The aim of the present study was to investigate the accuracy of CE in this setting, comparing the clinical, endoscopic and histological data.This was a retrospective single-centre study that included 57 (mean age: 47.18±15.05 years, 57.89% men) patients presenting with GVHD who underwent a valid CE and histopathological analysis by conventional endoscopy between January 2004 and July 2016. The endoscopic scored findings, clinical data and histopathological diagnosis were compared using duodenal histology as the gold standard.CE detected mild (n=4, 7.02%), moderate (n=6, 10.53%) and severe (n=21, 36.84%) grades, with a higher diagnostic yield than conventional endoscopy (54.39 vs. 28.07%, P0.001). A positive CE predicted positive histology (80.64 vs. 15.38%, P0.001) with a sensitivity, specificity, negative predictive value and accuracy of 86.21, 78.57, 84.62 and 82.46%. This procedure detected more mild-to-moderate histological lesions than conventional endoscopy (8.77 vs. 3.51%, P=0.25). In addition, 16% of patients with a previous normal endoscopy with biopsies had a pathological CE and there were eight (25.81%) patients with positive CE images unreachable by conventional endoscopy.CE is a useful device in GVHD, achieving high accuracy values and diagnostic yield. However, its results may be interpreted in conjunction with clinical and histological features, particularly in mild-to-moderate stages.
- Published
- 2016
24. La enteropatía de intestino delgado por antiinflamatorios no esteroideos y la hemorragia digestiva de origen oscuro
- Author
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Noé Quesada-Vázquez, Enrique Pérez-Cuadrado-Martínez, Enrique Pérez-Cuadrado-Robles, Blanca Martínez-Andrés, Antonio López-Higueras, José María Rubio-Mateos, and José Francisco Sánchez-Melgarejo
- Subjects
03 medical and health sciences ,0302 clinical medicine ,Hepatology ,business.industry ,030220 oncology & carcinogenesis ,Gastroenterology ,Medicine ,030211 gastroenterology & hepatology ,business ,Humanities - Published
- 2018
25. Pólipo fibroso inflamatorio (de Vaneck) como origen de hemorragia digestiva de origen oscuro
- Author
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Marta Aicart Ramos, Enrique Pérez-Cuadrado Robles, Javier Martínez-González, Paloma Bebia Conesa, Enrique Pérez-Cuadrado Martínez, and María Isabel López-Espín
- Subjects
medicine.medical_specialty ,Hepatology ,medicine.diagnostic_test ,business.industry ,Anemia ,Internal medicine ,Gastroenterology ,medicine ,Colonoscopy ,business ,medicine.disease - Published
- 2015
26. Diagnosis agreement between capsule endoscopy and double-balloon enteroscopy in obscure gastrointestinal bleeding at a referral center
- Author
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José Luis Rodrigo-Agudo, Eduardo Domingo Muñoz-Bertrán, Emilio Torrella-Cortés, Luis Eduardo Zamora-Nava, Hacibe Hallal, Octavio López-Albors, Enrique Pérez-Cuadrado-Robles, Enrique Pérez-Cuadrado-Martínez, Paloma Bebia-Conesa, Silvia Chacón-Martínez, Federico Soria, Antonio López-Higueras, Pilar Esteban-Delgado, Rafael Latorre, Blanca Martínez-Andrés, and J. Shanabo
- Subjects
Adult ,Male ,Angioectasia ,medicine.medical_specialty ,Hemorragia digestiva media ,Capsule Endoscopy ,Angiodysplasia ,law.invention ,Tertiary Care Centers ,Capsule endoscopy ,law ,Double-balloon enteroscopy ,Cápsula endoscópica ,Humans ,Medicine ,lcsh:RC799-869 ,Enteroscopy ,Lesión de Dieulafoy ,Aged ,Retrospective Studies ,Dieulafoy's lesion ,Double-Balloon Enteroscopy ,Gynecology ,medicine.diagnostic_test ,business.industry ,Gastroenterology ,General Medicine ,Middle Aged ,Obscure gastrointestinal bleeding ,Enteroscopia ,Referral center ,lcsh:Diseases of the digestive system. Gastroenterology ,Female ,Gastrointestinal Hemorrhage ,business - Abstract
espanolIntroduccion y objetivo: la capsula endoscopica y la enteroscopia de doble balon son tecnicas de reconocido valor en el estudio de la hemorragia digestiva media, habiendo numerosos factores que pueden afectar a su rendimiento diagnostico. El objetivo del presente estudio es el de caracterizar y definir los niveles de concordancia entre ambas focalizando en el tipo de lesion, en una gran cohorte de pacientes de un centro de referencia. Material y metodo: entre los anos 2004-2014 se administraron 1.209 capsulas en 1.078 pacientes y se realizaron 381 enteroscopias en 361 pacientes con hemorragia digestiva media. Resultados: en 332 pacientes (edad media: 65,22 ± 15,41, 183 hombres) se realizaron ambos procedimientos. Ambas tecnicas tuvieron un rendimiento diagnostico similar (70,5% vs. 69,6%, p = 0,9). El rendimiento diagnostico global de la enteroscopia fue superior en pacientes con una capsula previa positiva (79,3% vs. 27,9%, p 0,55-0,77]), tumores (0,66 [95% IC: 0,55-0,76]) y moderada para ulceras (0.56 [95% IC: 0,46-0,67]). Los diverticulos (0,39 [95% IC: 0,29-0,5] tuvieron una concordancia razonable. Los resultados entre ambos procedimientos difirieron en 73 pacientes (22%). Conclusiones: el presente estudio evidencia que aunque el rendimiento de la capsula endoscopica y la enteroscopia de doble balon de forma global sean similares, hay numerosos factores que pueden modificar estos valores, siendo el principal el tipo de lesion. EnglishBackground and aim: Capsule endoscopy and doubleballoon enteroscopy are well-recognized procedures in obscure gastrointestinal bleeding, with many factors that may influence their diagnosis yield. The aim of the present study was to characterize the degree of agreement between both techniques with focus on the type of lesion in a large cohort of patients at a referral center. Material and method: One thousand two hundred and nine capsules were administered in 1,078 patients and 381 enteroscopies were performed in 361 patients with obscure-gastrointestinal bleeding from 2004 to 2014. Results: Both procedures were carried out in 332 patients (mean age: 65.22 ± 15.41, 183 men) and they have a similar diagnosis yield (70.5% vs. 69.6%, p = 0.9). Overall enteroscopy diagnosis yield was higher within patients with a previous positive capsule endoscopy (79.3% vs. 27.9%, p 0.46-0.67]). Diverticula (0.39 [95% CI: 0.29-0.5]) achieved a fair agreement. The results of CE and DBE differed in 73 patients (22%). Conclusions: The present study confirms that although overall diagnostic yield by capsule endoscopy and double-balloon enteroscopy is similar, there are many factors which can modify these values, mainly the type of lesion.
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- 2015
27. Response
- Author
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Enrique Perez-Cuadrado-Robles and Enrique Pérez-Cuadrado Martínez
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Double-Balloon Enteroscopy ,Crohn Disease ,Intestine, Small ,Gastroenterology ,Humans ,Radiology, Nuclear Medicine and imaging ,Capsule Endoscopy - Published
- 2014
28. Role of capsule endoscopy in suspected celiac disease: A European multi-centre study
- Author
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Noelia Alonso-Lázaro, Julio Valle-Muñoz, José Francisco Juanmartiñena Fernández, Enrique Pérez-Cuadrado-Martínez, Cristina Carretero-Ribón, Santiago Gonzalez-Vazquez, Ignacio Fernandez-Urien-Sainz, Pilar Borque-Barrera, César Prieto-de-Frías, Begoña González-Suárez, Marisol Luján-Sanchis, Luca Elli, Federica Branchi, Federico Argüelles-Arias, Victoria Alejandra Jiménez-García, Juan Egea-Valenzuela, Sofia Xavier, Antonio López-Higueras, Francisco Sanchez-Ceballos, Javier Sempere-Garcia-Argüelles, Enrique Pérez-Cuadrado-Robles, Vicente Pons-Beltrán, Juan Manuel Herrerías-Gutiérrez, Lucıa Ruano-Dıaz, Bruno Rosa, Mileidis San-Juan-Acosta, Javier Garcıa-Lledo, [Luján-Sanchis,M, Sempere-García-Argüelles,J] Digestive Diseases Unit, General University Hospital of Valencia, Valencia, Spain. [Pérez-Cuadrado-Robles,E, López-Higueras,A, Pérez-Cuadrado-Martínez,E] Small Bowel Unit, Hospital Morales Meseguer, Murcia, Spain. [Sánchez-Ceballos,F] Digestive Diseases Unit, General University Gregorio Marañón, Madrid, Spain. [Juanmartiñena Fernández JF, Fernández-Urién-Sainz,I] Unit of Gastroenterology and Endoscopy, Complejo Hospitalario de Navarra, Pamplona, Spain. [Elli,L, Branchi,F] Center for Prevention and Diagnosis of Celiac Disease, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy. [Jiménez-García,VA, Argüelles-Arias,F, Herrerías-Gutiérrez,JM] Unit of Gastroenterology and Endoscopy, University Hospital Virgen Macarena, Sevilla, Spain. [Egea-Valenzuela,J] Gastroenterology Department, Hospital Virgen de la Arrixaca, Murcia, Spain. [Valle-Muñoz,J, Ruano-Díaz,I] Department of Gastroenterology, Complejo Hospitalario de Toledo, Toledo, Spain. [Carretero-Ribón,C, González-Vázquez,S, Prieto-De-Frías,C] Department of Gastroenterology, University of Navarra Clinic, Pamplona, Spain. [Alonso-Lázaro,N, Pons-Beltrán,V] Endoscopy Digestive Unit, Digestive Diseases Area, Universitari i Politècnic la Fe Hospital, Valencia, Spain. [Sanjuan-Acosta,M, Borque-Barrera,P] Digestive Diseases Unit, University Hospital Nuestra Señora de Candelaria, Tenerife, Spain. [Sánchez-Ceballos,F] Digestive Diseases Unit, Clinical Hospital San Carlos, Madrid, Spain. [Rosa,B, and Xavier,S] Digestive Diseases Unit, Hospital da Senhora da Oliveira - Guimarães, Cutileiros, Portugal. [González-Suárez,B] Endoscopy Digestive Unit, Hospital Clinic de Barcelona, Barcelona, Spain.
- Subjects
Male ,Diseases::Digestive System Diseases::Gastrointestinal Diseases::Gastroenteritis::Inflammatory Bowel Diseases::Crohn Disease [Medical Subject Headings] ,Enfermedad celíaca ,Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Case-Control Studies::Retrospective Studies [Medical Subject Headings] ,Non-celiac gluten sensitivity ,Anatomy::Digestive System::Gastrointestinal Tract::Intestines::Intestine, Small::Jejunum [Medical Subject Headings] ,Named Groups::Persons::Age Groups::Adult::Middle Aged [Medical Subject Headings] ,Capsule Endoscopy ,Gastroenterology ,law.invention ,Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings] ,0302 clinical medicine ,law ,Prevalence ,Celiac disease ,Medicine ,Capsule endoscopy ,Child ,Diseases::Digestive System Diseases::Gastrointestinal Diseases::Intestinal Diseases [Medical Subject Headings] ,Aged, 80 and over ,General Medicine ,Middle Aged ,Endoscopía capsular ,Europe ,medicine.anatomical_structure ,Diseases::Pathological Conditions, Signs and Symptoms::Pathological Conditions, Anatomical::Atrophy [Medical Subject Headings] ,030220 oncology & carcinogenesis ,Gluten-free diet ,Female ,030211 gastroenterology & hepatology ,Patient Safety ,Adult ,medicine.medical_specialty ,Adolescent ,Observational Study ,Context (language use) ,Phenomena and Processes::Physiological Phenomena::Nutritional Physiological Phenomena::Diet [Medical Subject Headings] ,Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnosis, Differential [Medical Subject Headings] ,Diet, Gluten-Free ,Young Adult ,03 medical and health sciences ,Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Diagnostic Techniques, Digestive System::Endoscopy, Digestive System::Endoscopy, Gastrointestinal::Gastroscopy [Medical Subject Headings] ,Atrophy ,Internal medicine ,Gastroscopy ,Named Groups::Persons::Age Groups::Adult [Medical Subject Headings] ,Humans ,Enfermedad de Crohn ,Villous atrophy ,Contraindication ,Aged ,Retrospective Studies ,business.industry ,Histology ,Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Diagnostic Techniques, Surgical::Endoscopy::Endoscopy, Digestive System::Endoscopy, Gastrointestinal::Capsule Endoscopy [Medical Subject Headings] ,Anti-transglutaminase antibodies ,medicine.disease ,Diseases::Digestive System Diseases::Gastrointestinal Diseases::Intestinal Diseases::Malabsorption Syndromes::Celiac Disease [Medical Subject Headings] ,Celiac Disease ,Check Tags::Female [Medical Subject Headings] ,Atrofia ,Duodenum ,Anatomy::Digestive System::Gastrointestinal Tract::Intestines::Intestine, Small::Duodenum [Medical Subject Headings] ,Differential diagnosis ,business - Abstract
AIM To analyze the diagnostic yield (DY), therapeutic impact (TI) and safety of capsule endoscopy (CE). METHODS This is a multi-centre, observational, analytical, retrospective study. A total of 163 patients with suspicion of celiac disease (CD) (mean age = 46.4 ± 17.3 years, 68.1% women) who underwent CE from 2003 to 2015 were included. Patients were divided into four groups: seronegative CD with atrophy (Group- ?, n = 19), seropositive CD without atrophy (Group- ?, n = 39), contraindication to gastroscopy (Group-?, n = 6), seronegative CD without atrophy, but with a compatible context (Group-?, n = 99). DY, TI and the safety of CE were analysed. RESULTS The overall DY was 54% and the final diagnosis was villous atrophy (n = 65, 39.9%), complicated CD (n = 12, 7.4%) and other enteropathies (n = 11, 6.8%; 8 Crohn's). DY for groups ? to ? was 73.7%, 69.2%, 50% and 44.4%, respectively. Atrophy was located in duodenum in 24 cases (36.9%), diffuse in 19 (29.2%), jejunal in 11 (16.9%), and patchy in 10 cases (15.4%). Factors associated with a greater DY were positive serology (68.3% vs 49.2%, P = 0.034) and older age (P = 0.008). On the other hand, neither sex nor clinical presentation, family background, positive histology or HLA status were associated with DY. CE results changed the therapeutic approach in 71.8% of the cases. Atrophy was associated with a greater TI (92.3% vs 45.3%, P < 0.001) and 81.9% of the patients responded to diet. There was one case of capsule retention (0.6%). Agreement between CE findings and subsequent histology was 100% for diagnosing normal/other conditions, 70% for suspected CD and 50% for complicated CD. CONCLUSION CE has a high DY in cases of suspicion of CD and it leads to changes in the clinical course of the disease. CE is safe procedure with a high degree of concordance with histology and it helps in the differential diagnosis of CD. © The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved. Yes
- Published
- 2017
29. Evidences supporting the vascular etiology of post-double balloon enteroscopy pancreatitis: Study in porcine model
- Author
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Octavio López-Albors, Pilar Esteban, Rafael Latorre, Esther Morcillo, Enrique Pérez-Cuadrado-Martínez, Enrique Pérez-Cuadrado-Robles, and Federico Soria
- Subjects
Vascular Endothelial Growth Factor A ,Pathology ,medicine.medical_specialty ,Swine ,Sus scrofa ,Gastroenterology ,Necrosis ,03 medical and health sciences ,0302 clinical medicine ,Animal model ,Risk Factors ,Internal medicine ,Double-balloon enteroscopy ,Intestine, Small ,medicine ,Animals ,Humans ,Hypoxia ,Pancreas ,Biochemical markers ,Hyperamylasemia ,Double-Balloon Enteroscopy ,Microscopy ,Pig ,medicine.diagnostic_test ,Pancreatic tissue ,business.industry ,Minireviews ,General Medicine ,medicine.disease ,Double balloon enteroscopy ,Intestines ,Disease Models, Animal ,Intestinal Diseases ,medicine.anatomical_structure ,Pancreatitis ,030220 oncology & carcinogenesis ,Amylases ,Etiology ,030211 gastroenterology & hepatology ,business ,Perfusion ,Biomarkers - Abstract
Double balloon enteroscopy (DBE) is an endoscopic technique broadly used to diagnose and treat small bowel diseases. Among the associated complications of the oral DBE, post-procedure pancreatitis has taken the most attention due to its gravity and the thought that it might be associated to the technique itself and anatomical features of the pancreas. However, as the etiology has not been clarified yet, this paper aims to review the published literature and adds new results from a porcine animal model. Biochemical markers, histological sections and the vascular perfusion of the pancreas were monitored in the pig during DBE practice. A reduced perfusion of the pancreas and bowel, the presence of defined hypoxic areas and disseminated necrotic zones were found in the pancreatic tissue of pigs. All these evidences contribute to support a vascular distress as the most likely etiology of the post-DBE pancreatitis.
- Published
- 2017
30. Schwannoma pericárdico. La ecoendoscopia como herramienta de apoyo en el estudio de lesiones cardiacas
- Author
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Enrique Pérez-Cuadrado Martínez, Paloma Bebia-Conesa, Aurelio López-Martín, and Matías Pérez-Paredes
- Subjects
Hepatology ,business.industry ,Gastroenterology ,Medicine ,business ,Humanities - Published
- 2014
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