Background/aims: Obesity is one of the most serious public health problems. Laparoscopic sleeve gastrectomy (LSG), a type of bariatric surgery, is emerging as the new promising therapy for the treatment of morbid obesity., Methodology: In the present study we aimed to assess the effects of LSG on body weight and other obesity related pathological conditions., Results: A total of 19 obese subjects underwent LSG surgery. All patients underwent complete evaluation including anthropometric/clinical parameters and laboratory tests. Hypertension (HT), diabetes mellitus (DM), body mass index (BMI), and hyperlipidemia were significantly reduced after LSG., Conclusions: Results of this study demonstrate that LSG induces stable weight loss and resolution of obesity-associated comorbidities.