1. Recognizing and overcoming potential barriers to oral medications for MS.
- Author
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Moses H Jr
- Subjects
- Administration, Oral, Crotonates adverse effects, Crotonates pharmacology, Dimethyl Fumarate, Fingolimod Hydrochloride, Fumarates adverse effects, Fumarates pharmacology, Humans, Hydroxybutyrates, Immunosuppressive Agents adverse effects, Immunosuppressive Agents pharmacology, Nitriles, Propylene Glycols adverse effects, Propylene Glycols pharmacology, Sphingosine administration & dosage, Sphingosine adverse effects, Sphingosine pharmacology, Toluidines adverse effects, Toluidines pharmacology, Crotonates administration & dosage, Fumarates administration & dosage, Immunosuppressive Agents administration & dosage, Multiple Sclerosis drug therapy, Propylene Glycols administration & dosage, Sphingosine analogs & derivatives, Toluidines administration & dosage
- Abstract
Three FDA-approved oral medications are available for the treatment of relapsing forms of multiple sclerosis: fingolimod, teriflunomide, and dimethyl fumarate. While injection and IV treatments have proven to be beneficial, these newer oral agents also offer positive outcomes for patients. Numerous barriers exist, though, for these oral agents, including the unknown long-term efficacy and safety and potential side effects. Despite possible side effects, oral agents provide convenience, ease of use, and the elimination of injection/IV administration-site pain. To ensure MS patients receive the most appropriate individualized care, clinicians should present all of the available treatment options to both newly diagnosed and established patients., (© Copyright 2014 Physicians Postgraduate Press, Inc.)
- Published
- 2014
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