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Your search keyword '"Iida, Takehiko"' showing total 2 results
Start Over Author "Iida, Takehiko" Topic fluorination -- physiological aspects
2 results on '"Iida, Takehiko"'

1. Synthesis of a muscarinic receptor antagonist via a diastereoselective Michael reaction, selective deoxyfluorination and aromatic metal-halogen exchange reaction

Author

Mase, Toshiaki, Houpis, Ioannis N., Akao, Atsushi, Dorziotis, Ilias, Emerson, Khateeta, Hoang, Thoa, Iida, Takehiko, Itoh, Takahiro, Kamei, Keisuke, Kato, Shinji, Kato, Yoshiaki, Kawasaki, Masashi, Lang, Fengrui, Lee, Jaemoon, Lynch, Joseph, Maligres, Peter, Molina, Audrey, Nemoto, Takayuki, Okada, Shigemitsu, Reamer, Robert, Song, Jake Z., Tschaen, David, Wada, Toshihiro, Zewge, Daniel, Volante, R. P., Reider, Paul J., and Tomimoto, Koji

Subjects
Chemistry, Organic -- Research, Muscarinic receptors -- Physiological aspects, Aromatic compounds -- Physiological aspects, Metals -- Physiological aspects, Halogens -- Physiological aspects, Fluorination -- Physiological aspects, Amines -- Physiological aspects, Amides -- Physiological aspects, Acids -- Physiological aspects, Biological sciences, Chemistry
Abstract

Research has been conducted on the M (sub)3 antagonist. The synthesis of this structurally unique antagonist has been carried out and the results indicate that after being disconnected retrosynthetically at the amide bond it revealed the acid portion and amine fragment.

Published
2001

2. Synthesis of a muscarinic receptor antagonist via a diastereoselective Michael reaction, selective deoxyfluorination and aromatic metal-halogen exchange reaction

Author

Mase, Toshiaki, Houpis, Ioannis N., Akao, Atsushi, Dorziotis, Ilias, Emerson, Khateeta, Hoang, Thoa, Iida, Takehiko, Itoh, Takahiro, Kamei, Keisuke, Kato, Shinji, Kawasaki, Masashi, Lang, Fengrui, Lee, Jaemoon, Lynch, Joseph, Maligres, Peter, Molina, Audrey, Nemoto, Takayuki, Okada, Shigemitsu, Reamer, Robert, Song, Zhiguo J., Tschaen, David, Wada, Toshihiro, Zewge, David, Volante, R. P., Reider, Paul J., and Tomimoto, Koji

Subjects
Chemistry, Organic -- Research, Halogens -- Physiological aspects, Aromatic compounds -- Physiological aspects, Fluorination -- Physiological aspects, Muscarinic receptors -- Physiological aspects, Biological sciences, Chemistry
Published
2002

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