1. Red emissive fluorescent probe for the rapid detection of selenocysteine.
- Author
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Zhang, Panpan, Ding, Ying, Liu, Weimin, Niu, Guangle, Zhang, Hongyan, Ge, Jiechao, Wu, Jiasheng, Li, Yanqing, and Wang, Pengfei
- Subjects
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FLUORESCENT probes , *SELENOCYSTEINE , *IMAGING systems , *XANTHENE , *BENZENESULFONATES - Abstract
A novel fluorescent probe O-hNRSel based on tetralin-xanthene fused dye O-hNR was designed and synthesized by introducing 2,4-dinitrobenzenesulfonate functionality. This probe is able to detect selenocysteine (Sec) with rapid response time (2 min) and a large fluorescence enhancement at 624 nm (124-fold). O-hNRSel exhibited selective response to Sec over many other analy and high sensitivity with the detection limit as low as 17 nM. Furthermore, O-hNRSel has been used for fluorescent imaging of Sec in living cells with good biocompatibility. [ABSTRACT FROM AUTHOR]
- Published
- 2018
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