1. A portable illumination device for photodynamic therapy of the oral cavity.
- Author
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Xiong, Jiyuan, Wang, Xu, Hu, Xiaoming, Han, Ying, and Li, Qin
- Subjects
- *
PHOTODYNAMIC therapy , *ORAL leukoplakia , *FLEXIBLE printed circuits , *LIGHTING , *SURFACE temperature , *MAXIMUM power point trackers - Abstract
Photodynamic therapy (PDT) is a minimally invasive method for treating oral leukoplakia. In this paper, we propose a portable PDT device consisting of a flexible circuit board with a liquid flow cooling module on the back. The light source size was 17 mm × 1 1 mm × 4 mm, and the irradiation area of the light source was up to 100 mm2. The irradiance range of this device was from 10 mW/cm2 to 100 mW/cm2. Simulation and experimental results showed that the irradiance coefficient variation for a treatment area of 81 mm2 was less than 7%. At an irradiance of 100 mW/cm2, a device surface temperature of lower than 42∘C can be achieved to satisfy the safety requirements under the conditions that the temperature of cooling liquid is 10∘C and the liquid flow speed is above 12 mL/min. [ABSTRACT FROM AUTHOR]
- Published
- 2022
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