Highlights • Build vibration transmission path system models according to the concept of vibration source, transfer path and receiving structure. • Define transmission reliability pattern of resonance problem. • Define transmission reliability sensitivity to distribution characteristics of path parameters. • Explore theoretical analysis method of transmission reliability and reliability sensitivity and derive general calculation formulas. Abstract The vibration transmission path systems are generally composed of the vibration source, the vibration transfer path and the vibration receiving structure. The transfer path is the medium of the vibration transmission. Therefore, the uncertainty of path parameters influences the system reliability greatly. In order to avoid the resonance failure, the transmission reliability analysis and the reliability sensitivity analysis are both very important. Based on the reliability theory, the absolute value difference of natural frequency and excitation frequency of random vibration transmission path system was limited and the reliability pattern of the resonance problem was defined in this paper. Applying the generalized second moment technique of vector-valued functions and the stochastic finite element theory, the theoretical analysis method of the transmission reliability and reliability sensitivity was presented. The corresponding vibration transmission path system with uncertain path parameters including mass, stiffness and path position was analyzed theoretically and computed numerically, and then the correlated mathematical expressions were obtained. Thus, in practical project, most of uncertain factors in the vibration systems can be analyzed so that the effective way can be given to avoid resonance failure. [ABSTRACT FROM AUTHOR]