1. Chronic polyarthritis associated to Cercopithifilaria bainae infection in a dog.
- Author
-
Gabrielli S, Giannelli A, Brianti E, Dantas-Torres F, Bufalini M, Fraulo M, La Torre F, Ramos RA, Cantacessi C, Latrofa MS, Cancrini G, and Otranto D
- Subjects
- Animals, Anthelmintics therapeutic use, Arthritis diagnosis, Arthritis drug therapy, Arthritis parasitology, Chronic Disease, Dog Diseases drug therapy, Dog Diseases parasitology, Dogs, Filariasis diagnosis, Filariasis drug therapy, Filariasis parasitology, Filarioidea drug effects, Filarioidea genetics, Italy, Macrolides therapeutic use, Microfilariae, Sequence Analysis, DNA veterinary, Synovial Fluid parasitology, Tick-Borne Diseases diagnosis, Tick-Borne Diseases drug therapy, Tick-Borne Diseases parasitology, Arthritis veterinary, Dog Diseases diagnosis, Filariasis veterinary, Filarioidea isolation & purification, Tick-Borne Diseases veterinary
- Abstract
Despite the widespread distribution of Cercopithifilaria bainae among canine and tick populations worldwide, this filarioid is currently considered of 'minor importance' in veterinary medicine, particularly when compared to related filarioids, such as Dirofilaria immitis and Dirofilaria repens. To date, only a single case of dermatological alterations possibly associated to infection by C. bainae had been reported in a dog. In the present study, we describe the first case of systemic alterations associated to C. bainae infection in a dog suffering from diffused chronic polyarthritis. The animal had a previous history of reluctance to move and stiff gait and displayed multiple joint pain during manipulation of limbs. No biochemical, haematological and X-ray alterations were detected; microfilariae were observed in the synovial fluids collected from the joints. In spite of the morphological and molecular identification of these microfilariae as C. bainae, the dog did not respond to multiple microfilaricidal treatments with milbemicyn oxyme. The potential role of C. bainae in the pathogenesis of this clinical condition is discussed. Given the potential pathogenicity of this parasite, improved knowledge of this little known tick-borne nematode is warranted in order to assist the development of novel and effective treatment strategies., (Copyright © 2014. Published by Elsevier B.V.)
- Published
- 2014
- Full Text
- View/download PDF