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Background: Abscess, an infection with viable infecting organisms and polymorphonuclear cells, contained within a fibrous capsule, limiting the infection, and preventing its further spread. It may be monomicrobial or polymicrobial. Aims and Objectives: The aims of the study were to determine microbiological profile of abscesses of different body sites and associated complications. Materials and Methods: An observational study was conducted in our department with 35 pus samples from abscesses of different body sites between August 2022 and December 2022. Gram stain, Z-N stain, fungal stain, aerobic, anaerobic, and fungal culture were performed. Statistical analysis was done by statistical tool R. Results: Out of 35 samples-limb, liver,paraspinal, psoas, appendicular, breast, perineal, ear, brain and lung abscesses were 11,4,2,3,1,7,2,2,2,1 respectively. Most common organisms from limb,ear,paraspinal and breast abscesses was MRSA (Methicillin resistant Staphylococcal aureus). Also most common organisms were – Escherichia coli from liver abscess, Enterobacteriaceae and Pseudomonas aeruginosa from psoas and appendicular abscess, Enterobacter aerogenes from perineal, Escherichia coli and Actinomyces species from brain and Candida auris from lung abcesses. No growth were also found in few samples. Their susceptibility testing showed-MRSA strains susceptible to both Vancomycin and Linezolid, gram negative bacteria were susceptible to Cephalosporins, Piperacillin-tazobactam, Carbapenems, polymixins, etc. C.auris was resistant to all antifungals. Their blood samples were also collected - ten patients showed fever with bacteremia and one with candidemia . They were treated with systemic antimicrobials along with drainage and/or surgical resection. Conclusion: Abscesses must be suspected in cases with non-resolving fever with/without septicemia and treated promptly with appropriate antimicrobials based on susceptibility report and with drainage and/or surgical resection.

Introduction- Omicron is subdivided into BA.1 and BA.2. BA.2 appears to be more transmissible by nature. The new BA.2 sub variant is 30% easier to spread than the original omicron variant. Among those who are infected, headache, sore/itchy throat, sneezing, runny nose, and general body soreness are the most prevalent symptoms. Dizziness and fatigue are two more Omicron BA.2 sub variant symptoms. The aim of the study to evaluate the clinical variability of the BA. 2 sub variant. Material and methods- A retrospective study was conducted from December 2021 – March 2022 at VRDL, department of microbiology, R. G Kar medical college and hospital. Clinical features, demographic status, comorbidity status was evaluated. Result - Common symptoms of BA.2 variants are headache, sore throat, fever, muscle pain shortness of breath, runny nose, fatigue, loss of taste, chest pain, diarrhea. Other unusual symptoms are chills, altered smell, eye soreness, swollen glands, rash, hoarse voice. The risk of severe disease was similarly lower for unvaccinated cases during the Omicron period, but it remained high for older persons and middle-aged men with comorbidities. Hospitalization was rare for this variant but affected more the unvaccinated infant group. However, future evolution of the BA.2 sub variant, as well as potential emergent sub variants, should be properly monitored.

Background: Abscess, an infection with viable infecting organisms and polymorphonuclear cells, contained within a fibrous capsule, limiting the infection, and preventing its further spread. It may be monomicrobial or polymicrobial. Aims and Objectives: The aims of the study were to determine microbiological profile of abscesses of different body sites and associated complications. Materials and Methods: An observational study was conducted in our department with 35 pus samples from abscesses of different body sites between August 2022 and December 2022. Gram stain, Z-N stain, fungal stain, aerobic, anaerobic, and fungal culture were performed. Statistical analysis was done by statistical tool R. Results: Out of 35 sampleslimb, liver, paraspinal, psoas, appendicular, breast, perineal, ear, brain and lung abscesses were 11,4,2,3,1,7,2,2,2,1 respectively. Most common organisms from limb, ear, paraspinal and breast abscesses was MRSA (Methicillin resistant Staphylococcal aureus). Also most common organisms were - Escherichia coli from liver abscess, Enterobacteriaceae and Pseudomonas aeruginosa from psoas and appendicular abscess, Enterobacter aerogenes from perineal, Escherichia coli and Actinomyces species from brain and Candida auris from lung abcesses. No growth were also found in few samples. Their susceptibility testing showed-MRSA strains susceptible to both Vancomycin and Linezolid, gram negative bacteria were susceptible to Cephalosporins, Piperacillin-tazobactam, Carbapenems, polymixins, etc. C.auris was resistant to all antifungals. Their blood samples were also collected - ten patients showed fever with bacteremia and one with candidemia. They were treated with systemic antimicrobials along with drainage and/or surgical resection. Conclusion: Abscesses must be suspected in cases with non-resolving fever with/without septicemia and treated promptly with appropriate antimicrobials based on susceptibility report and with drainage and/or surgical resection. [ABSTRACT FROM AUTHOR]

Introduction: Omicron is subdivided into BA.1 and BA.2. BA.2 appears to be more transmissible by nature. The new BA.2 sub variant is 30% easier to spread than the original omicron variant. Among those who are infected, headache, sore/itchy throat, sneezing, runny nose, and general body soreness are the most prevalent symptoms. Dizziness and fatigue are two more Omicron BA.2 sub variant symptoms. The aim of the study to evaluate the clinical variability of the BA. 2 sub-variants. Material and methods: A retrospective study was conducted from December 2021 - March 2022 at VRDL, department of microbiology, R. G Kar medical college and hospital. Clinical features, demographic status, comorbidity status was evaluated. Result: Common symptoms of BA.2 variants are headache, sore throat, fever, muscle pain shortness of breath, runny nose, fatigue, loss of taste, chest pain, diarrhea. The risk of severe disease was remained high for older persons and middle-aged men with comorbidities. Hospitalization was rare for this variant but affected more the unvaccinated infant group. Conclusion: The future evolution of the BA.2 sub variant, as well as potential emergent sub variants, should be properly monitored. Omicron BA.2 will infect populations and become another common concerned variation. [ABSTRACT FROM AUTHOR]