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[Objective]The main wine-making grape production areas in the eastern foothills of Helan mountain were confronted with the problems such as excessive dependence on chemical fertilizer, poor soil and long-term continuous cropping, which resulted in the decline of soil sustainable production capacity and the decline of wine grape quality, etc. The effects of fertilizer reduction on soil fertility and wine grape quality in the eastern foothills of Helan mountain were studied. [Method] Using the four years old wine grape variety Cabernet Sauvignon (Cabernet Sauvignon) as the research object, set no fertilizer; 100% chemical fertilizer; 100% organic fertilizer; 50% chemical fertilizer, 50% organic fertilizer; 100% soil conditioning agent and 25% chemical fertilizer, 25% organic fertilizer, 100% soil conditioning, total six treatments to study the effect of fertilizer reduction on wine grape quality and soil fertility. [Result]The results showed that the effect of chemical fertilizer halving on soil fertility was not significant compared with that of total fertilizer application. But the content of anthocya-nin increased 132.9 % in half of chemical fertilizer treatment compared with total fertilizer application, organic matter content in orchard soil was significantly increased by using organic fertilizer instead of chemical fertilizer, and soil organic matter content was significantly increased in soil available nutrients. The content of available potassium and available phosphorus increased by 55.05%, 130.2% and 3.08%, respectively, and the content of soluble sugar of wine grape berries was significantly increased by applying organic fertilizer. The yield of chemical fertilizer and organic fertilizer decreased by 75 % in combination with soil conditioner, and the yield increased by 69.07%, but the comprehensive quality of grape berry decreased significantly. [Conclusion] In alkaline calcareous soil at the eastern foot of Ilelan mountain, adding soil conditioner can effectively improve soil environment and improve grape quality, and excessive reduction of chemical fertilizer is not conducive to the production of high quality wine grape raw materials, It is an effective measure to improve soil fertility, wine grape quality and economic benefit by halving fertilizer and applying organic fertilizer. [ABSTRACT FROM AUTHOR]