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Your search keyword '"U. Bunescu"' showing total 5 results
Start Over Author "U. Bunescu" Topic female
5 results on '"U. Bunescu"'

1. Improvement of hematological and general tolerance to CMF by high-dose medroxyprogesterone acetate (HD-MPA) adjuvant treatment for primary node positive breast cancer (analysis of 100 patients)

Author

C, Focan, A, Baudoux, M, Beauduin, U, Bunescu, N, Dehasque, L, Dewasch, J P, Lobelle, E, Longeval, F, Majois, and E, Salamon

Subjects
Adult, Clinical Trials as Topic, Medroxyprogesterone, Platelet Count, Breast Neoplasms, Medroxyprogesterone Acetate, Middle Aged, Hemoglobins, Leukocyte Count, Random Allocation, Methotrexate, Antineoplastic Combined Chemotherapy Protocols, Humans, Drug Interactions, Female, Fluorouracil, Cyclophosphamide, Aged
Abstract

In a prospective randomized trial comparing CMF to CMF + HD-MPA for primary node positive breast cancer patients, the authors evidenced clear improvement of hematological tolerance (especially of WBC - granulocytes counts) to chemotherapy in the group receiving also hormonotherapy. The design of the trial allowed to give the patients overall high doses of CMF therapy in both arms; in the group receiving HD-MPA significantly higher doses of CMF could be administered (96.3-97.8% for CMF + HD-MPA treated patients vs 89.7-91.1% for CMF alone treated patients). The menopausal status did not influence the results.

Published
1986

2. [Total body electron therapy of mycosis fungoides]

Author

E, Salamon, P, Piret, J C, Dardenne, U, Bunescu, A, Baudoux, and A, Vindevoghel

Subjects
Adult, Male, Radiotherapy, High-Energy, Mycosis Fungoides, Skin Neoplasms, Humans, Female, Particle Accelerators, Whole-Body Irradiation
Published
1984

3. Radiation therapy of carcinomas of the skin of nose and nasal vestibule: a report of 1676 cases by the Groupe Europeen de Curiethérapie

Author

P. Serpantie, S. Hoffstetter, C. Maylin, Jean-Jacques Mazeron, J.B. Dubois, M. Koechlin, N. Daly, U. Bunescu, F. Brochet, J. Crook, S. Danczak, M. Grangean, A. Reynaud-Bougnoux, Judith Huart, F. Bachelot, M. Madelain, D. Brune, F. Brunin, D. Chassagne, R. Rozan, and A. Labib

Subjects
Nasal cavity, Adult, Male, medicine.medical_specialty, Esthetics, medicine.medical_treatment, Population, Brachytherapy, Nose Neoplasms, Nose neoplasm, Radiotherapy, High-Energy, medicine, Humans, Multicenter Studies as Topic, Radiology, Nuclear Medicine and imaging, education, Nose, Aged, Retrospective Studies, Aged, 80 and over, education.field_of_study, business.industry, Cosmesis, Hematology, Middle Aged, Surgery, Radiation therapy, medicine.anatomical_structure, Oncology, Carcinoma, Basal Cell, Carcinoma, Squamous Cell, Female, Nasal vestibule, Nasal Cavity, Neoplasm Recurrence, Local, business, Nuclear medicine, Follow-Up Studies
Abstract

A retrospective multicentric analysis of the results of irradiation of 1676 carcinomas of the skin of the nose and nasal vestibule was performed by the Groupe Europeen de Curietherapie (Tunis, May 1986). Overall local control was 93% with a minimum follow-up of 2 years. Local control is dependent on the tumor size (diameter less than 2 cm: 96%, 2-3.9 cm: 88%, greater than or equal to 4 cm: 81%), and tumor site (external surface of the nose: 94%, vestibule: 75%). Local control was independent of histology for smaller tumors, but for those larger than 4 cm, basal cell carcinomas were more frequently controlled than squamous cell carcinomas. Recurrent tumors are less frequently controlled than those being treated for the first time (88 vs. 95%). There were few complications and cosmetic results were generally satisfactory. The results of implantation, orthovoltage and megavoltage irradiation are compared with respect to local control, complication rate and cosmesis. Implantation is usually the treatment of choice for vestibular tumors but for those of the external surface the choice depends on the tumor diameter. Implantation and orthovoltage irradiation are equivalent for tumors less than 2 cm. For those from 2 to 3.9 cm, the results of orthovoltage irradiation may be satisfactory in a selected population but implantation is usually more suitable for tumors with rapidly changing contour.(ABSTRACT TRUNCATED AT 250 WORDS)

Published
1988

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