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3 results on '"Sidoti, V"'

1. Trauma and amyotrophic lateral sclerosis: a case-control study from a population-based registry

Author

Pupillo, E., Messina, P., Logroscino, G., Zoccolella, S., Chio, A., Calvo, A., Corbo, M., Lunetta, C., Micheli, A., Millul, A., Vitelli, E., Beghi, E., Bissolati, M., Formaglio, F., Gerardi, F., Giussani, G., Maestri, E., Prelle, A., Protti, A., Riva, N., Santoro, D., Al-Chalabi, A., Berro, A. C., De Mercanti, S., Giacone, S., Ilardi, A., Hardiman, O., Capozzo, R., Ludolph, A., Mitchell, D., Preux, P. -M., Swingler, R., van den Berg, L., Alvisi, E., Cereda, C., Ceroni, M., Citterio, A., di Poggio, M. B., Caponnetto, C., Buzzi, P., Colombo, I., Cotelli, M. S., Filosto, M., Padovani, A., De Lodovici, L., Ferrarese, C., Tremolizzo, L., Fetoni, V., Palazzini, E., Guaita, M. C., Perrone, P., Secchi, P., Lorusso, L., Sidoti, V., Perini, M., Tavernelli, F., Rigamonti, A., Pupillo, E, Messina, P, Logroscino, G, Zoccolella, S, Chiò, A, Calvo, A, Corbo, M, Lunetta, C, Micheli, A, Millul, A, Vitelli, E, Beghi, E, Bissolati, M, Formaglio, F, Gerardi, F, Giussani, G, Maestri, E, Prelle, A, Protti, A, Riva, N, Santoro, D, Al Chalabi, A, Berro, A, De Mercanti, S, Giacone, S, Ilardi, A, Hardiman, O, Capozzo, R, Ludolph, A, Mitchell, D, Preux, P, Swingler, R, van den Berg, L, Alvisi, E, Cereda, C, Ceroni, M, Citterio, A, di Poggio, M, Caponnetto, C, Buzzi, P, Colombo, I, Cotelli, M, Filosto, M, Padovani, A, De Lodovici, L, Ferrarese, C, Tremolizzo, L, Fetoni, V, Palazzini, E, Guaita, M, Perrone, P, Secchi, P, Lorusso, L, Sidoti, V, Perini, M, Tavernelli, F, and Rigamonti, A

Subjects
Male, ALS, trauma, risk, medicine.medical_specialty, Pediatrics, Epidemiology, Population, Poison control, Trauma, 03 medical and health sciences, 0302 clinical medicine, Injury prevention, Humans, Medicine, Registries, 030212 general & internal medicine, Amyotrophic lateral sclerosis, education, Aged, education.field_of_study, business.industry, Amyotrophic Lateral Sclerosis, Case-control study, Odds ratio, Middle Aged, medicine.disease, 3. Good health, Risk factors, Neurology, Case-Control Studies, Multivariate Analysis, Physical therapy, Wounds and Injuries, Population study, Female, Neurology (clinical), business, 030217 neurology & neurosurgery
Abstract

BACKGROUND AND PURPOSE: Published reports on the association between amyotrophic lateral sclerosis (ALS) and trauma are controversial suggesting the need for a new case-control study done in a large population. METHODS: A case-control study was undertaken in Italy to assess this association. Cases were patients with newly diagnosed ALS from four population-based registries. For each case, two hospital controls were selected, matched for age, sex, and province of residence, one with a neurological (non-degenerative) disease and one with a non-neurological disease (other than orthopedic or surgical). Traumatic events (defined as accidental events causing injuries requiring medical care) were recorded with details on type, site, timing, severity, and complications. The risks were assessed as odds ratios (ORs) with 95% confidence intervals (CI), crude and adjusted for age, sex, education, interviewee (patient or surrogate), physical activity, smoking, alcohol, and coffee. RESULTS: The study population comprised 377 patients in each of the three groups. One or more traumatic events were reported by 225 cases (59.7%), 191 neurological controls (50.7%), and 179 non-neurological controls (47.5%) (P

Published
2012

2. Breast cancer 'tailored follow-up' in Italian oncology units: a web-based survey

Author

Natoli, C., Brocco, D., Sperduti, I., Nuzzo, A., Tinari, N., De Tursi, M., Grassadonia, A., Mazzilli, L., Iacobelli, S., Gamucci, T., Vici, P., Study, Group, Adamo, V., Airoldi, M., Amoroso, D., Angelini, F., Angiolini, C., Angiolucci, G., Ardizzoia, A., Baldini, E., Ballardini, P., Barni, S., Barone, C., Battelli, N., Bernardi, D., Bianchetti, S., Bianco, N., Biglia, Nicoletta, Bilancia, D., Biti, G., Boni, C., Bordonaro, R., Botta, M., Bretti, S., Brunello, A., Brunetti, C., Bruno, D., Bucci, E., Buzzoni, R., Cagossi, K., Cappelletti, C., Cappuzzo, F., Cardillo, F., Carroccio, R., Cascinu, S., Cavanna, L., Cianchetti, E., Clerico, M., Contu, A., Corsi, D., Cortesi, L., Cretella, E., Crispino, S., Di Lieto, M., Di Lullo, L., Durini, E., Fabi, A., Failla, G., Fattorusso, S., Ferraù, F., Ferro, A., Ficorella, C., Fogazzi, G., Foglietta, J., Francini, G., Fusco, O., Gennari, A., Ghiani, M., Gianni, L., Giordano, M., Giotta, F., Giuliani, R., Gori, S., Graiff, C., Guarneri, V., Guarneri, D., Guglielmi, F., Landriscina, M., Laudadio, L., Lombardo, M., Longo, F., Macellari, G., Madeddu, C., Magnanini, S., Maiorino, L., Mangiameli, A., Marini, G., Massidda, B., Mattioli, R., Michelotti, A., Molino, A., Montesarchio, V., Morale, A., Murgo, R., Naso, G., Natale, D., Orditura, M., Orrù, S., Pace, R., Palazzo, A., Palma, F., Pancotti, A., Pandoli, G., Papaldo, P., Parisi, A. M., Passalacqua, R., Pellegrino, A., Perrucci, B., Proietti, E., Recchia, F., Riccardi, F., Rispoli, A. I., Rocca, A., Romaniello, I., Rossetti, R., Rossi, D., Rosti, G., Ruggeri, E. M., Russo, A., Savarino, A., Savastano, C., Scognamiglio, G., Scognamiglio, M., Seminara, P., Serrachini, S., Sidoti, V., Silva, R. R., Surace, G., Tomao, S., Tonini, G., Trenta, P., Turazza, M., Valenza, R., Veltri, E., Zampa, G., Zaniboni, A., Zanirato, S., C, Natoli, D, Brocco, I, Sperduti, A, Nuzzo, N, Tinari, M, De Tursi, A, Grassadonia, L, Mazzilli, S, Iacobelli, T, Gamucci, P, Vici, Study Group, 'FOLLOW-UP', and Orditura, Michele

Subjects
Oncology, breast cancer, Follow-up, survey, Medical Oncology, law.invention, Randomized controlled trial, law, Aged, Breast Neoplasms, Female, Follow-Up Studies, Health Care Surveys, Humans, Italy, Middle Aged, Secondary Prevention, Guideline Adherence, Breast Tumors, Medicine and Health Sciences, Web based survey, Multidisciplinary, Pharmaceutics, Surgical Oncology, Cancer Therapy, Medicine, medicine.symptom, Disease staging, Research Article, medicine.medical_specialty, Adjuvant Cancer Chemotherapy, Science, MEDLINE, Asymptomatic, Breast cancer, Drug Therapy, Internal medicine, medicine, Cancer Detection and Diagnosis, Chemotherapy, Modalities, business.industry, Cancers and Neoplasms, medicine.disease, Blood chemistry, Women's Health, Clinical Medicine, business
Abstract

PurposeBreast cancer follow-up procedures after primary treatment are still a controversial issue. Aim of this study was to investigate, through a web-based survey, surveillance methodologies selected by Italian oncologists in everyday clinical practice.MethodsReferents of Italian medical oncology units were invited to participate to the study via e-mail through the SurveyMonkey website. Participants were asked how, in their institution, exams of disease staging and follow-up are planned in asymptomatic women and if surveillance continues beyond the 5th year.ResultsBetween February and May 2013, 125 out of 233 (53.6%) invited referents of Italian medical oncology units agreed to participate in the survey. Ninety-seven (77.6%) referents state that modalities of breast cancer follow-up are planned according to the risk of disease progression at diagnosis and only 12 (9.6%) oncology units apply the minimal follow-up procedures according to international guidelines. Minimal follow-up is never applied in high risk asymptomatic women. Ninety-eight (78.4%) oncology units continue follow-up in all patients beyond 5 years.ConclusionsOur survey shows that 90.4% of participating Italian oncology units declare they do not apply the minimal breast cancer follow-up procedures after primary treatment in asymptomatic women, as suggested by national and international guidelines. Interestingly, about 80.0% of interviewed referents performs the so called "tailored follow-up", high intensity for high risk, low intensity for low risk patients. There is an urgent need of randomized clinical trials able to determine the effectiveness of risk-based follow-up modalities, their ideal frequency and persistence in time.

Published
2014

3. Coffee and Amyotrophic Lateral Sclerosis: A Possible Preventive Role

Author

Beghi, E., Pupillo, E., Messina, P., Giussani, G., Chio, A., Zoccolella, S., Moglia, C., Corbo, M., Logroscino, G., Al-Chalabi, A., Hardiman, O., Ludolph, A., Mitchell, D., Preux, P. -M., Swingler, R., Traynor, B. J., Alvisi, E., Cereda, C., Ceroni, M., Citterio, A., di Poggio, M. B., Caponnetto, C., Bissolati, M., Buzzi, P., Colombo, I., Formaglio, F., Lunettam, C., Maestri, E., Millul, A., Prelle, A., Protti, A., Riva, N., Santoro, D., Capozzo, R., Berro, A. C., Cammarosano, S., Giacone, S., Ilardi, A., Cotelli, M. S., Filosto, M., Micheli, A., Padovani, A., De Lodovici, L., Ferrarese, C., Tremolizzo, L., Fetoni, V., Palazzini, E., Guaita, M. C., Perrone, P., Secchi, P., Lorusso, L., Sidoti, V., Perini, M., Tavernelli, F., Rigamonti, A., Vitelli, E., Beghi, E, Pupillo, E, Messina, P, Giussani, G, Chiò, A, Zoccolella, S, Moglia, C, Corbo, M, Logroscino, G, Ferrarese, C, and Tremolizzo, L

Subjects
amyotrophic lateral sclerosis, coffee, motor neuron disease, Adult, Male, medicine.medical_specialty, Epidemiology, Coffee, Young Adult, Risk Factors, Internal medicine, Coffee intake, medicine, Odds Ratio, Humans, Young adult, Amyotrophic lateral sclerosis, Inverse correlation, Aged, Aged, 80 and over, business.industry, Risk Factor, Amyotrophic Lateral Sclerosis, Case-control study, Odds ratio, Middle Aged, medicine.disease, Confidence interval, Surgery, Italy, Case-Control Studies, Cohort, Female, business, Case-Control Studie, Human, Amyotrophic Lateral Sclerosi
Abstract

The relation between coffee intake and risk of amyotrophic lateral sclerosis (ALS) was investigated in 377 newly diagnosed ALS patients from 4 Italian population-based registries in the European ALS Consortium (EURALS Group) (2007-2010). For each patient, 2 age- and sex-matched hospital controls were selected, one from a neurology department and one from a nonneurologic department. Two additional healthy control groups were identified from local general practitioners' (GPs') lists (n = 99) and residents of the same area as a cancer cohort (n = 7,057). Coffee intake was defined in terms of status (ever consuming coffee daily for ≥6 months vs. never), duration, and history (never, former, or current). Ever coffee drinkers comprised 74.7% of ALS patients, 80.4% of neurologic controls, 85.6% of nonneurologic controls (P = 0.0004), 88.9% of GP controls (P = 0.0038), and 86.0% of cancer cohort controls (P < 0.0001). Current coffee drinkers comprised 60.2% of ALS patients, 70.2% of neurologic controls (P = 0.0294), 76.4% of nonneurologic controls (P < 0.0001), and 82.3% of GP controls (P = 0.0002); duration of intake was ≥30 years for 62.3%, 67.7%, 74.7%, and 72.6%. ALS patients had lower lifetime coffee exposure: Odds ratios were 0.7 (95% confidence interval (CI): 0.5, 1.1), 0.6 (95% CI: 0.4, 0.8), and 0.4 (95% CI: 0.2, 0.9) in comparison with neurologic, nonneurologic, and GP controls, respectively. In current (vs. never) coffee drinkers, odds ratios were 0.7 (95% CI: 0.5, 1.0), 0.5 (95% CI: 0.3, 0.7), and 0.4 (95% CI: 0.2, 0.8), respectively. These findings provide epidemiologic evidence of an inverse correlation between coffee intake and ALS risk.

Published
2011

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