1. Long-Term Follow-Up of Pericardium for the Ventricular Component in Atrioventricular Septal Defect Repair
- Author
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Rinske IJsselhof, Martijn G. Slieker, Mark G. Hazekamp, Saniyé D R Duchateau, Paul H. Schoof, and R. M. Schouten
- Subjects
Male ,Reoperation ,congenital, hereditary, and neonatal diseases and abnormalities ,medicine.medical_specialty ,Complete atrioventricular septal defect ,Long term follow up ,congenital heart surgery ,030204 cardiovascular system & hematology ,03 medical and health sciences ,0302 clinical medicine ,Internal medicine ,medicine ,Animals ,Humans ,Pericardium ,Atrioventricular Septal Defect ,atrioventricular septal defect ,Cardiac Surgical Procedures ,Retrospective Studies ,Mitral regurgitation ,Atrioventricular valve ,business.industry ,Heart Septal Defects ,Infant ,General Medicine ,Treatment Outcome ,medicine.anatomical_structure ,030228 respiratory system ,Pediatrics, Perinatology and Child Health ,Cardiology ,Cattle ,Female ,Surgery ,mitral regurgitation ,Cardiology and Cardiovascular Medicine ,business ,Follow-Up Studies - Abstract
Background: Despite the improved outcome in complete atrioventricular septal defect (AVSD) repair, reoperations for left atrioventricular valve (LAVV) dysfunction are common. The aim of this study was to evaluate the effect of fresh untreated autologous pericardium for ventricular septal defect (VSD) closure on atrioventricular valve function and compare the results with the use of treated bovine pericardial patch material. Methods: Clinical and echocardiographic data were collected of patients with complete AVSD with their VSD closed with either untreated autologous pericardial or treated bovine pericardial patch material between January 1, 1996, and December 31, 2003. Evaluation closed in September 2019. Results: A total of 77 patients were analyzed (untreated autologous pericardial VSD patch: 59 [77%], treated bovine pericardial VSD patch: 18 [23%]). Median age at surgery was 3.6 (interquartile range [IQR]: 2.7-4.5) months, and median weight was 4.5 (IQR: 3.9-5.1) kg. Trisomy 21 was present in 70 (91%) patients. Median follow-up time was 17.5 (IQR: 12.6-19.8) years. Death Conclusions: In AVSD, the VSD can safely be closed with either untreated autologous pericardium or xeno-pericardium. We found no difference in LAVV regurgitation or the need for reoperation between the two patches.
- Published
- 2020