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Although children frequently engage in creative activities (in which they make foods and objects by hand), the development and scope of children’s thinking about handmade items is largely unexplored. In the present studies, we examined whether 4- to 12-year-old children at a local children’s museum (54% girls, 46% boys; 51% White, 11% Asian/Asian-American, 10% more than one group, 4% Latinx, 3% Black/African-American, 18% did not report race/ethnicity) would expect other people to prefer handmade over factory-made items, including foods and nonfoods. In Experiments 1 (n = 124) and 2 (n = 122), participants expected a child character to prefer items the character made themselves and items made by the character’s parent or a local person. However, this expectation did not persist at all costs: When considering imperfect handmade items in Experiment 3 (n = 122), children demonstrated a handmade preference when considering nonfoods made by a parent but demonstrated a factory-made preference when considering foods made by a parent. Children’s explanations were associated with their choices: When children’s explanations referred to emotions or relationships, they were more likely to select handmade items. When children referred to item features, they were more likely to select factory-made items. Across studies, we observed persistent age and gender effects: Children’s handmade preference increased with child age and girls demonstrated a more robust handmade preference than boys. These findings highlight children’s developing and nuanced reasoning about object value. At an early age, children consider who made an object as a contributor to its value.

Individuals and cultures share some commonalities in food preferences, yet cuisines also differ widely across social groups. Eating is a highly social phenomenon; however, little is known about the judgments children make about other people’s food choices. Do children view conventional food choices as normative and consequently negatively evaluate people who make unconventional food choices? In five experiments, 5-year-old children were shown people who ate conventional and unconventional foods, including typical food items paired in unconventional ways. In Experiment 1, children preferred conventional foods and conventional food eaters. Experiment 2 suggested a link between expectations of conventionality and native/foreign status; children in the United States thought that English speakers were relatively more likely to choose conventional foods than French speakers. Yet, children in Experiments 3 and 4 judged people who ate unconventional foods as negatively as they judged people who ate canonical disgust elicitors and nonfoods, even when considering people from a foreign culture. Children in Experiment 5 were more likely to assign conventional foods to cultural ingroup members than to cultural outgroup members; nonetheless, they thought that no one was likely to eat the nonconventional items. These results demonstrate that children make normative judgments about other people’s food choices and negatively evaluate people across groups who deviate from conventional eating practices.

Understanding disease transmission is a complex problem highlighted by the COVID-19 pandemic. These studies test whether 3- to 6-year-old children in the United States use information about social interactions to predict disease transmission. Before and during COVID-19, children predicted illness would spread through close interactions. Older children outperformed younger children with no associations between task performance and pandemic experience. Children did not predict that being hungry or tired would similarly spread through close interactions. Participants include 196 three- to six-year-olds (53% girls, 47% boys; 68% White, 9% Black, 7% Asian, 6% Hispanic or Latinx), with medium-sized effects (d = .6, η p 2 = .3). These findings suggest that thinking about social interaction supports young children's predictions about illness, with noted limitations regarding children's real-world avoidance of disease-spreading behaviors.

Though parental modeling is thought to play a critical role in promoting children's healthy eating, little research has examined maternal food intake and maternal food talk as independent predictors of children's food intake. The present study examines maternal food talk during a structured eating protocol, in which mothers and their children had the opportunity to eat a series of familiar and unfamiliar vegetables and desserts. Several aspects of maternal talk during the protocol were coded, including overall food talk, directives, pronoun use, and questions. This study analyzed the predictors of maternal food talk and whether maternal food talk and maternal food intake predicted children's food intake during the protocol. Higher maternal body mass index (BMI) predicted lower amounts of food talk, pronoun use, and questions. Higher child BMI z-scores predicted more first person pronouns and more wh-questions within maternal food talk. Mothers of older children used fewer directives, fewer second person pronouns, and fewer yes/no questions. However, maternal food talk (overall and specific types of food talk) did not predict children's food intake. Instead, the most robust predictor of children's food intake during this protocol was the amount of food that mothers ate while sitting with their children. These findings emphasize the importance of modeling healthy eating through action and have implications for designing interventions to provide parents with more effective tools to promote their children's healthy eating.

Past research finds that monolingual and bilingual children prefer native speakers to individuals who speak in unfamiliar foreign languages or accents. Do children in bilingual contexts socially distinguish among familiar languages and accents and, if so, how do their social preferences based on language and accent compare? The present studies tested whether 5- to 7- year-old children in two bilingual contexts in the United States demonstrate social preferences among the languages and accents that are present in their social environments. We compared children’s preferences based on language (i.e., English versus their other native language) and their preferences based on accent (i.e., English with a native accent versus English with a non-native, yet familiar, accent). In Experiment 1, children attending a French immersion school demonstrated no preference between English and French speakers, but preferred American-accented English to French-accented English. In Experiment 2, bilingual Korean-American children demonstrated no preference between English and Korean speakers, but preferred American-accented English to Korean-accented English. Across studies, bilingual children’s preferences based on accent (i.e., American-accented English over French- or Korean-accented English) was not related to their own language dominance. These results suggest that children from diverse linguistic backgrounds demonstrate social preferences for native-accented speakers. Implications for understanding the potential relation between social reasoning and language acquisition are discussed.

Encouraging children to participate in food preparation is recommended by pediatric guidelines and has been included in public health interventions. However, little is known about whether the act of preparing a food specifically increases children's intake of that food, nor is it known whether this effect might differ for healthy and familiar unhealthy foods. The present study examines whether 5- to 7-year-old children eat more of a food they prepared themselves compared to the same food prepared by someone else. Children participated in a laboratory study in which they prepared either a salad or a dessert and then had the opportunity to eat the food they prepared and/or a nearly identical food prepared by someone else. We found that children ate more of a food they prepared themselves, but no significant difference was observed in children's ratings of each food. In addition to eating more healthy foods they prepared themselves, children ate more unhealthy foods they prepared themselves, including familiar and well-liked desserts. More specific recommendations are needed if the goal of involving children in food preparation is to promote health.

Adults implicitly judge people from certain social backgrounds as more "American" than others. This study tests the development of children's reasoning about nationality and social categories. Children across cultures (White and Korean American children in the United States, Korean children in South Korea) judged the nationality of individuals varying in race and language. Across cultures, 5- to 6-year-old children (N = 100) categorized English speakers as "American" and Korean speakers as "Korean" regardless of race, suggesting that young children prioritize language over race when thinking about nationality. Nine- and 10-year-olds (N = 181) attended to language and race and their nationality judgments varied across cultures. These results suggest that associations between nationality and social category membership emerge early in life and are shaped by cultural context.

Does contextual information about disgust influence children's food consumption and subjective experience of taste? Three- to eight-year-old children (N = 60) were presented with two identical foods, yet children were led to believe that one food had been contaminated by sneezing and licking, while the other was clean. When given the opportunity to eat the foods, 5- to 8-year-old children consumed more clean food and rated the clean food's taste more positively; younger children did not distinguish between the foods. The relation between contamination and subjective taste held even among children who ate both foods and had direct evidence that they were identical. These data indicate that children's consumption behavior and food preferences are influenced by information external to foods themselves.

How does social information affect the perception of taste early in life? Does mere knowledge of other people’s food preferences impact children’s own experience when eating? In Experiment 1, 5- and 6-year-old children consumed more of a food described as popular with other children than a food that was described as unpopular with other children, even though the two foods were identical. In Experiment 2, children ate more of a food described as popular with children than a food described as popular with adults. Experiment 3 tested whether different perceptual experiences of otherwise identical foods contributed to the mechanisms underlying children’s consumption. After sampling both endpoints of a sweet-to-sour range (applesauce with 0 mL or 5mL of lemon juice added), children were asked to taste and categorize applesauce samples with varying amounts of lemon juice added. When classifying ambiguous samples that were near the midpoint of the range (2 mL and 3 mL), children were more likely to categorize popular foods as sweet as compared to unpopular foods. Together, these findings provide evidence that social information plays a powerful role in guiding children’s consumption and perception of foods. Broader links to the sociality of food selection are discussed.

Study Design: Case report. Objectives: To describe the first use of intravenous (IV) ketamine as the sole agent in a patient-controlled analgesic delivery system (ie PCA) in a patient with cervical syringomyelia. Setting: A tertiary-care university teaching hospital in New York City. Methods: A 41-year-old tetraplegic female on high-dose opioids suffering from intractable dysesthetic central pain received her best pain relief from a low-dose ketamine infusion after failing trials with multiple neuropathic medications. After several weeks of titrating her infusion rate up and down, she was switched to an IV ketamine PCA device. Results: The patient was maintained on an IV ketamine PCA for almost 1 year under the following settings: 2.7 mg/h basal rate; 2.7 mg/h demand dose; 15 min lockout period. Although she continues to report some pain, it has dramatically decreased since the ketamine PCA was instituted, enabling us to significantly reduce her opioid dosage. Conclusions: Ketamine PCA may be a viable treatment option in patients suffering from intractable central pain. The rationale for this treatment, along with dosing guidelines and possible drawbacks, is discussed.

Adults evaluate others based on their speech, yet little is known of the developmental trajectory by which accent attitudes are acquired. Here we investigate the development of American children's attitudes about Northern- and Southern-accented American English. Children in Illinois (the “North”) and Tennessee (the “South”) evaluated the social desirability, personality characteristics, and geographic origins of Northern- and Southern-accented individuals. Five- to 6-year-old children in Illinois preferred the Northern-accented speakers as potential friends, yet did not demonstrate knowledge of any stereotypes about the different groups; 5–6-year-old children in Tennessee did not show a preference towards either type of speaker. Nine- to 10-year-old children in both Illinois and Tennessee evaluated the Northern-accented individuals as sounding “smarter” and “in charge”, and the Southern-accented individuals as sounding “nicer.” Thus, older children endorse similar stereotypes to those observed in adulthood. These accent attitudes develop in parallel across children in different regions and reflect both positive and negative assessments of a child's own group.

For more than 20 years, primary prevention of coronary heart disease has included strategies intended to improve overall serum lipid concentrations among youths.To examine trends in lipid concentrations among youths from 1988-1994 through 2007-2010.Cross-sectional analysis of serum lipid concentrations among 16,116 youths aged 6 to 19 years who participated in the nationally representative National Health and Nutrition Examination Survey during 3 time periods: 1988-1994, 1999-2002, and 2007-2010.Among all youths, mean serum total cholesterol (TC), non-high-density lipoprotein cholesterol (non-HDL-C), high-density lipoprotein cholesterol (HDL-C); and among adolescents only, low-density lipoprotein cholesterol (LDL-C) and geometric mean triglyceride levels. Trends in adverse lipid concentrations are reported for TC levels of 200 mg/dL and greater, non-HDL-C levels of 145 mg/dL and greater, HDL-C levels of less than 40 mg/dL, LDL-C levels of 130 mg/dL and greater, and triglyceride levels of 130 mg/dL and greater.Among youths aged 6 to 19 years between 1988-1994 and 2007-2010, there was a decrease in mean TC (from 165 mg/dL [95% CI, 164-167] to 160 mg/dL [95% CI, 158-161]; P.001) and a decrease in the prevalence of elevated TC (from 11.3% [95% CI, 9.8%-12.7%] to 8.1% [95% CI, 6.7%-9.5%]; P = .002). Mean HDL-C significantly increased between 1988-1994 and 2007-2010, but the prevalence of low HDL-C did not change. Mean non-HDL-C and prevalence of elevated non-HDL-C both significantly decreased over the study period. In 2007-2010, 22% (95% CI, 20.3%-23.6%) of youths had either a low HDL-C level or high non-HDL-C, which was lower than the 27.2% (95% CI, 24.6%-29.7%) in 1988-1994 (P = .001). Among adolescents (aged 12-19 years) between 1988-1994 and 2007-2010, there was a decrease in mean LDL-C (from 95 mg/dL [95% CI, 92-98] to 90 mg/dL [95% CI, 88-91]; P = .003) and a decrease in geometric mean triglycerides (from 82 mg/dL [95% CI, 78-86] to 73 mg/dL [95% CI, 70-76]; P.001). Prevalence of elevated LDL-C and triglycerides between 1988-1994 and 2007-2010 also significantly decreased.Between 1988-1994 and 2007-2010, a favorable trend in serum lipid concentrations was observed among youths in the United States but almost 1 in 10 had elevated TC in 2007-2010.

Three experiments investigated 5- to 6-year-old monolingual English-speaking American children's sociolinguistic evaluations of others based on their accent (native, foreign) and social actions (nice, mean, neutral). In Experiment 1, children expressed social preferences for native-accented English speakers over foreign-accented speakers, and they judged the native-accented speakers to be 'American.' In Experiments 2 and 3, the accented speakers were depicted as being nicer than the relatively meaner native speakers. Children's social preferences and judgments of others' personalities varied as a function of behavior; in particular, children disliked individuals who committed negative social actions. In contrast, children's judgments of nationality hinged exclusively on accent; across all conditions, children evaluated native-accented English speakers to be 'American,' regardless of whether they were nice or mean. These findings contribute to an understanding of the nature of children's reasoning about language as a social category and have implications for future research investigating children's thinking about language as a marker of national group identity.

The psychoneuroimmunology of panic disorder is relatively unexplored. Alterations within brain stress systems that secondarily influence the immune system have been documented. A recent report indicated elevations of serotonin (5-HT) and ganglioside antibodies in patients with primary fibromyalgia, a condition with documented associations with panic disorder. In line with our interest in dysregulated 5-HT systems in panic disorder (PD), we wished to assess if antibodies directed at the 5-HT system were elevated in patients with PD in comparison to healthy volunteers. Sixty-three patients with panic disorder and 26 healthy volunteers were diagnosed by the SCID. Employing ELISA, we measured anti-5-HT and 5-HT anti-idiotypic antibodies (which are directed at 5-HT receptors). To include all subjects in one experiment, three different batches were run during the ELISA. Plasma serotonin anti-idiotypic antibodies: there was a significant group effect [patients > controls (p = .007)] and batch effect but no interaction. The mean effect size for the three batches was .76. Following Z-score transformation of each separate batch and then combining all scores, patients demonstrated significantly elevated levels of plasma serotonin anti-idiotypic antibodies. Neither sex nor age as covariates affected the significance of the results. There was a strong correlation between anti-serotonin antibody and serotonin anti-idiotypic antibody measures. Plasma anti-serotonin antibodies: there was a significant diagnosis effect [patients > controls (p = .037)]. Mean effect size for the three batches was .52. Upon Z-score transformation, there was a diagnosis effect with antibody elevations in patients. Covaried for sex and age, the result falls below significance to trend levels. The data raise the possibility that psychoimmune dysfunction, specifically related to the 5-HT system, may be present in PD. Potential interruption of 5-HT neurotransmission through autoimmune mechanisms may be of pathophysiologic significance in certain patients with panic disorder. It remains to be demonstrated if the peripheral autoimmunity is representative of CNS 5-HT neuronal alterations. Replication appears warranted.

A retrospective analysis of hallux abducto valgus surgery performed between 1990 and 1995 where the "Z" osteotomy and Kalish osteotomy were utilized was performed. Objective and subjective data were collected to determine the effectiveness of the Z osteotomy versus the Kalish osteotomy. Twenty cases of hallux abducto valgus where the Z osteotomy was utilized were evaluated on the basis of intermetatarsal angle correction and alleviation of preoperative symptoms. The same evaluation was performed on 21 cases where the Kalish osteotomy was utilized. There did not appear to be an appreciable difference in intermetatarsal angle correction between the two osteotomies; however, the Kalish osteotomy did alleviate preoperative symptoms to a greater degree compared with the Z osteotomy.