1. Amygdaloid theta-band power increases during conflict processing in humans
- Author
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Spencer Kellis, Yelim Lee, Kuang-Hsuan Chen, Charles Y. Liu, George Nune, Rinu Sebastian, Zachary D. Gilbert, Austin M. Tang, Roberto Martin Del Campo-Vera, Brian Lee, and Angad S. Gogia
- Subjects
Adult ,Male ,medicine.medical_specialty ,Emotions ,Local field potential ,Hippocampal formation ,Audiology ,Amygdala ,Task (project management) ,Conflict, Psychological ,Young Adult ,Physiology (medical) ,Reaction Time ,medicine ,Humans ,Emotional conflict ,Artifact (error) ,business.industry ,Electroencephalography ,General Medicine ,Middle Aged ,medicine.anatomical_structure ,Theta band ,Neurology ,Stroop Test ,Female ,Surgery ,Neurology (clinical) ,business ,Stroop effect - Abstract
The amygdala is a medial temporal lobe structure known to be involved in processing emotional conflict. However, its role in processing non-emotional conflict is not well understood. Previous studies have utilized the Stroop Task to examine brain modulation of humans under the color-word conflict scenario, which is non-emotional conflict processing, and found hippocampal theta-band (4-7 Hz) modulation. This study aims to survey amygdaloid theta power changes during non-emotional conflict processing using intracranial depth electrodes in nine epileptic patients (3 female; age 20-62). All patients were asked to perform a modified Stroop task. During task performance, local field potential (LFP) data was recorded from macro contacts sampled at 2 K Hz and used for analysis. Mean theta power change from baseline was compared between the incongruent and congruent task condition groups using a paired sample t-test. Seven patients were available for analysis after artifact exclusion. In five out of seven patients, statistically significant increases in theta-band power from baseline were noted during the incongruent task condition (paired sample t-test p 0.001), including one patient exhibiting theta power increases in both task conditions. Average response time was 1.07 s (failure trials) and 1.04 s (success trials). No speed-accuracy tradeoff was noted in this analysis. These findings indicate that human amygdaloid theta-band modulation may play a role in processing non-emotional conflict. It builds directly upon work suggesting that the amygdala processes emotional conflict and provides a neurophysiological mechanism for non-emotional conflict processing as well.
- Published
- 2021