1. Induction of labour from 39 weeks in low-risk multiparas with ripe cervixes: A randomised controlled trial
- Author
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Siti Zawiah Omar, Sandar Tin Win, Nurezwana Elias, Jesrine Gek Shan Hong, Aida Othman, and Peng Chiong Tan
- Subjects
Risk ,medicine.medical_specialty ,Caesarean delivery ,Bishop score ,Cervix Uteri ,law.invention ,03 medical and health sciences ,0302 clinical medicine ,Patient satisfaction ,Randomized controlled trial ,law ,Pregnancy ,Medicine ,Rupture of membranes ,Humans ,030212 general & internal medicine ,Labor, Induced ,030219 obstetrics & reproductive medicine ,Vaginal delivery ,business.industry ,Obstetrics ,Cesarean Section ,Infant, Newborn ,Obstetrics and Gynecology ,General Medicine ,Delivery, Obstetric ,Relative risk ,Female ,Labour Induction ,business - Abstract
BACKGROUND Induction of labour (IOL) in low-risk nulliparas at 39 weeks reduces caesarean delivery. Multiparas with ripe cervixes typically have vaginal delivery within eight hours. Delivery at night and weekend are associated with higher maternal and neonatal mortality. AIMS To evaluate IOL in full-term multiparas with ripe cervixes to achieve delivery at normal working hours and improve maternal satisfaction. METHODS A randomised trial was performed in a tertiary hospital in Malaysia. Low-risk multiparas with ripe cervixes (Bishop score ≥6) were recruited at 38+4 -40+0 weeks, then randomised to planned labour induction at 39+0 weeks or expectant care. Primary outcomes were delivery during 'normal working hours' 09:00-17:00 hours, Monday-Friday and patient satisfaction by visual numerical rating scale. RESULTS For IOL (n = 80) vs expectant care (n = 80) arms respectively, primary outcomes of delivery at normal working hours was 27/80 (34%) vs 29/78 (37%), relative risk (RR) 0.9, 95% CI 0.5-1.7, P = 0.41, patient satisfaction was 8.0 ± 1.8 vs 7.8 ± 1.6, P = 0.41; presentation for spontaneous labour or rupture of membranes were 27/80 (34%) vs 70/79 (89%), RR 0.4, 95% CI 0.3-0.5, P
- Published
- 2021