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Your search keyword '"Milenković Svetislav"' showing total 6 results
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6 results on '"Milenković Svetislav"'

1. Ocular rosacea and treatment of symptomatic Helicobacter pylori infection: a case series.

Author

Daković Z, Vesić S, Vuković J, Milenković S, Janković-Terzić K, Dukić S, and Pavlović MD

Subjects
Anti-Bacterial Agents therapeutic use, Drug Therapy, Combination, Eye Diseases pathology, Gastrointestinal Diseases drug therapy, Gastrointestinal Diseases microbiology, Helicobacter Infections drug therapy, Humans, Male, Middle Aged, Rosacea pathology, Eye Diseases complications, Gastrointestinal Diseases complications, Helicobacter Infections complications, Helicobacter pylori isolation & purification, Rosacea complications
Abstract

Rosacea is a chronic inflammatory skin disease characterized by recurrent episodes of facial flushing, erythema, papules, pustules, and telangiectasia. More than half of all rosacea patients may have ocular symptoms. Rosacea is associated with certain digestive diseases, such as gastritis, hypochlorhydria, or a number of jejunal mucosal abnormalities, and many patients have Helicobacter pylori infection. The role of Helicobacter pylori has often been a subject of investigation; these studies show conflicting results. Here we present results of the effects of treatment given for H. pylori eradication in seven patients with ocular rosacea that, at the same time, had clinical and serological evidence of H. pylori infection. Six weeks after completion of the treatment, all patients experienced improvement of their rosacea symptoms. Ocular disease responded better than cutaneous rosacea.

Published
2007

2. [Ocular rosacea].

Author

Daković Z, Vukićević-Sretenović J, Dobrosavljević D, and Milenković S

Subjects
Adult, Diagnosis, Differential, Female, Humans, Male, Middle Aged, Eye Diseases complications, Eye Diseases diagnosis, Eye Diseases drug therapy, Rosacea complications, Rosacea diagnosis, Rosacea drug therapy
Abstract

Five cases of ocular rosacea (one male and four females) are reported in this paper. Two of the patients were with keratoconjunctivitis sicca, one with conjunctivitis chronica and blepharitis, one with conjunctivitis chronica and meibomitis, and one with reccurent corneal erosions with meibomitis and chordeloum. In four patients ocular symptoms preceded the occurence of skin lesions. The treatment with oral tetracyclines significantly improved the state of ocular rosacea in four patients, while in one case the changes of the anterior eye segment progressed in more severe state of ulcerative keratitis. It is considered that in almost 20% of the patients with rosacea ocular lesions may precede the skin changes, representing a diagnostic problem. Thus, in those cases multidisciplinary approach is suggested. Such approach is particularly important because of the decrease of morbidity and the prevention of the onset of the eye complications such as drastic worsening of visual acuity, i.e., the blindness.

Published
2004
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3. [Rosacea as a multisystemic disease].

Author

Djaković Z, Milenković S, Pesko P, and Djukić N

Subjects
Humans, Rosacea drug therapy, Eye Diseases complications, Gastrointestinal Diseases complications, Rosacea complications
Abstract

Rosacea is a chronic skin disorder, affecting the face and chest, and develops mostly in the 3rd to 6th decades of life. It is characterized by erythema, telangiectasias, and recurrent flushings. During the time of this chronic inflammation, skin typically develops papules, pustules, and swelling. Ocular involvement occurs in 3 to 58% of patients with skin changes. Common ocular signs include blepharoconjunctivitis, meibomitis, and dry eyes. Rosacea keratitis, when present, however, has a poor prognosis and may lead to blindness. Among skin diseases, Helicobacter pylori infection has been often related with rosacea. A higher prevalence of indigestion and Helicobacter pylori infection in rosacea patients than in healthy controls has been reported. However, no causal relation has been identified. On the other hand, oral treatment with metronidazole is beneficial in all of three mentioned manifestations of rosacea (skin, eye, indigestion). There is obvious need for multidisciplinary approach, and investigation to rosacea.

Published
2003

4. Ocular rosacea

Author

Đaković Zorana, Vukićević-Sretenović Jelica, Dobrosavljević Danijela, and Milenković Svetislav

Subjects
eye diseases, acne rosacea, tetracyclines, doxycycline, Medicine (General), R5-920
Abstract

Five cases of ocular rosacea (one male and four females) are reported in this paper. Two of the patients were with keratoconjunctivitis sicca, one with conjunctivitis chronica and blepharitis, one with conjunctivitis chronica and meibomitis, and one with reccurent corneal erosions with meibomitis and chordeloum. In four patients ocular symptoms preceded the occurence of skin lesions. The treatment with oral tetracyclines significantly improved the state of ocular rosacea in four patients, while in one case the changes of the anterior eye segment progressed in more severe state of ulcerative keratitis. It is considered that in almost 20% of the patients with rosacea ocular lesions may precede the skin changes, representing a diagnostic problem. Thus, in those cases multidisciplinary approach is suggested. Such approach is particularly important because of the decrease of morbidity and the prevention of the onset of the eye complications such as drastic worsening of visual acuity, i.e., the blindness.

Published
2004
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5. Treatment with cyclosporine A in serpiginous choroiditis: A case report

Author

Kovačević Dragana, Detanac Dženana A, Marković Vujica, Radosavljević Aleksandra, Doklestić Krstina, Detanac Džemail S, and Milenković Svetislav

Subjects
Cyclosporine A, lcsh:R5-920, fluorescein angiography, serpiginous choroidopathy, sense organs, lcsh:Medicine (General), serpiginous choroiditis, eye diseases
Abstract

Serpiginous choroiditis is a rare clinical entity. The clinical course of serpiginous choroiditis is very variable, there is no universal marker of treatment success, and even among experts there is debate about what is the most appropriate treatment. The aim of this paper is to describe a case of serpiginous choroiditis treated with Cyclosporine A at a tertiary uveitis referral centre.

Published
2012

6. Influence of intravitreal treatment with angiogenesis inhibitors on functional and morphological findings in the wet form of age-related macular degeneration

Author

Risimić, Dijana S., Milenković, Svetislav, Prostran, Milica, Stojković, Milenko, Mavija, Milka, and Jakšić, Vesna

Subjects
FA, wet form of age-related macular degeneration, genetic structures, vaskularni endotelni faktor rasta, OCT, vascular endothelial growth factor, vlažna forma senilne degeneracije makule, BCVA, subretinalna neovaskularna membrana, FAG, bevacizumab, subretinal neovascular membrane, eye diseases
Abstract

Uvod: Senilna degeneracija makule (SDM) je vodeći uzrok ozbiljnog, trajnog oštećenja vida kod ljudi preko pedeset godina života. To je stanje kod koga primarno dolazi do oštećenja fotoreceptora makule. Subretinalna ili horoidalna neovaskularizacija je patološki supstrat za formiranje neovaskularne membrane (SNM) kod vlažne forme senilne degeneracije makule (nSDM). U patogenezi ove membrane značajnu ulogu, ako ne i ključnu, ima angiogenetski faktor, tzv. vaskularni endotelni faktor rasta (VEGF), koji je odgovoran za povećanje vaskularnog permeabiliteta i stimulaciju neovaskularizacije. Zato je jedna od mogućih strategija prevencije i tretmana subretinalne neovaskularne membrane inhibicija VEGF i smanjenje vaskularnog permeabiliteta. Cilj: je da se utvrditi efikasnost i bezbednost intravitrealne primene leka iz grupe ihhibitora VEGF, bevacizumaba u dozi od 1,25 mg (0,1mL) u terapiji nSDM, kao i da li intravitrealna primena ovog leka po PRN protokolu (pro-re-nata, ili po potrebi), utiče na promenu vidne oštrine (poboljšanje/stabilizacija/pogoršanje) i veličinu SNM merene optičkom koherentnom tomografijom (OCT) u periodu praćenja od 44±4 nedelje. Cilj ovog istraživanja je i da se utvrdi eventualni prognostički značaj vidne oštrine i vrste SNM ustanovljene fluoresceinskom angiografijom (FA) i OCT-om na krajnji ishod terapije. Takođe, jedan od ciljeva je i da se utvrde mogući lokalni i sistemsi neželjeni efekti intravitrealno aplikovanog bevacizumaba i njegov potencijalni efekat na promenu u vrednostima sistolnog i dijastolnog arterijskog krvnog pritiska, s obzirom da se lek primenjuje "off label". Metodologija: U retrospektivnu kliničku komparativnu studiju uključeno je 92 pacijenta sa dijagnozom nSDM. Dijagnoza nSDM je ustanovljena kliničkim pregledom, a potvrđena FA i OCT-om. Kriterijum uključenja bio je postojanje SNM tačno definisanog tipa (klasična, minimalno klasična ili okultna)... Introduction: Age-related macular degeneration (AMD) is the leading cause of serious, permanent sight damage after the age of fifty. In this condition macular photoreceptors are the primary sight of damage. Subretinal or choroidal neovascularization is the pathological substrate underlying the formation of a subretinal, choroidal neovascular membrane (CNM) in the wet form of age-related macular degeneration (wet AMD). In the pathogenesis of this membrane an important, if not crucial role is played by an angiogenesis factor known as vascular endothelial growth factor (VEGF), which is responsible for increasing the vascular permeability and stimulating neovascularization. Therefore, one of the possible strategies in the prevention and treatment of subretinal neovascular membrane is inhibition of VEGF and decrease in vascular permeability. Aim: is to determine the efficacy and safety of intravitreal administration of 1.25mg (0.1mL) of the vascular endothelial growth factor inhibitor bevacizumab in the treatment of wet AMD, as well as to determine whether PRN (pro-re-nata, or as needed) application of this drug has any influence on visual acuity (improvement/stabilization/deterioration) and the size of SNM measured by optical coherence tomography (OCT), in the follow-up period of 44±4 weeks. The aim of this research is also to determine the prognostic importance of visual acuity and CNM type determined by fluorescein angiography (FAG) and OCT on the outcome of treatment. Moreover, one of the aims is to determine the possible local or systemic side effects of the intravitreal application of bevacizumab and its potential effects on systolic and diastolic blood pressure, considering the “off label” application of the drug. Methodology: A total of 92 patients with the diagnosis of wet AMD were included in the retrospective clinical comparative study. The diagnosis of wet AMD was established by physical exam, and confirmed on FAG and OCT. The inclusion criterion was the existence of a particular type of SNM (classic, minimally classic or occult)...

Published
2015

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