1. Case series of therapeutic hypothermia for neonatal hypoxic-ischemic encephalopathy during extracorporeal life support.
- Author
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Bhandary P, Daniel JM, Skinner SC, Bacon MK, Hanna M, Bauer JA, Giannone P, and Ballard HO
- Subjects
- Data Collection, Extracorporeal Membrane Oxygenation methods, Female, Humans, Male, Brain Diseases therapy, Extracorporeal Membrane Oxygenation adverse effects, Hypothermia, Induced methods, Hypoxia-Ischemia, Brain therapy
- Abstract
Therapeutic hypothermia initiated within 6 hours of birth is currently the standard of care for the management of neonates with hypoxic-ischemic encephalopathy. Neonates undergoing therapeutic hypothermia for hypoxic-ischemic encephalopathy are also at risk for severe respiratory failure and need for extracorporeal life support. The risks and benefits of therapeutic hypothermia for hypoxic-ischemic encephalopathy during extracorporeal life support are still not well defined. We report our experience of a case series of six neonates who underwent therapeutic hypothermia for hypoxic-ischemic encephalopathy during extracorporeal life support. We also report long-term neurodevelopmental follow-up from 6 to 24 months and add to the current body of evidence regarding feasibility, clinical experience, and short-term complications.
- Published
- 2020
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