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The article considers nosogeography of leptospirosis focuses and analysis of different animal species disease incidence in the Republic of Kazakhstan with composition of nosographical and etiological map on spread of the diseases among cattle and pigs. Different animals’ leptospirosis is registered serologically and bacteriologically almost in all geographical zones: in the majority of cases among cattle and pigs, in a less degree among horses and sheep, in singularity among camels. Incidence of people disease with availability of natural and zoonotic focuses of leptospirosis infection has been studied on the territory of Kazakhstan Republic. Identity of leptospirosis etiological structure of people, farm animals and rodents, which is generally presented by leptospirosis serogroups Grippotyphosa, Pomona, Tarasovi, Hebdomadis at the leading significance of the first two, has been detected. In accordance with the rules of international sub-committee on taxonomy and nomenclature of Leptospira, identification of local Leptospira strains isolated from people and animals in Kazakhstan has been carried out for the first time. It was established that Leptospira of people and animals are caused by 7 serotypes (Grippotyphosa, Tarasovi, monjakov, sorex-jalna, sejroe, Saxkoebinq, Canicola) from 6 serogroups (Grippotyphosa, Tarasovi, Pomona, Iavanica, Hebdomadis, Canicola).