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1. Secondary extension of Hodgkin's disease to the skin with positive staining for EBV-encoded latent membrane protein.

Author

Ruiz-Genao, D. P., Daudén-Tello, E., G-F-Villalta, M. J., Fraga, J., and García-Díez, A.

Subjects
*HODGKIN'S disease, *LYMPHOMAS, *HIV-positive persons, *ONCOGENES, *CANCER genetics, *EPSTEIN-Barr virus
Abstract

Cutaneous involvement with Hodgkin's disease in HIV-positive patients is infrequent. Although the large majority of these cases are pathogenetically linked to Epstein-Barr virus, demonstration of viral oncogenes in skin involvement of Hodgkin's disease has rarely been performed. We report an HIV-positive male with aggressive Hodgkin's disease and specific cutaneous involvement. The presence of Epstein-Barr virus in cutaneous and lymph node samples could be demonstrated by a positive reaction to the Epstein-Barr virus latent-encoded membrane protein. [ABSTRACT FROM AUTHOR]

Published
2005
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