19 results on '"Suthar, Renu"'
Search Results
2. Metabolic epilepsy in hyperprolinemia type II due to a novel nonsense ALDH4A1 gene variant.
- Author
-
Kaur R, Paria P, Saini AG, Suthar R, Bhatia V, and Attri SV
- Subjects
- Amino Acid Metabolism, Inborn Errors complications, Brain diagnostic imaging, Codon, Nonsense, DNA genetics, Drug Resistant Epilepsy genetics, Electroencephalography, Epilepsy etiology, Female, Genetic Variation, Humans, Infant, Magnetic Resonance Imaging, Proline blood, Proline genetics, 1-Pyrroline-5-Carboxylate Dehydrogenase deficiency, 1-Pyrroline-5-Carboxylate Dehydrogenase genetics, Amino Acid Metabolism, Inborn Errors genetics, Epilepsy genetics
- Abstract
Hyperprolinemia type II (HPII) is a rare autosomal recessive disorder of proline degradation pathway due to deficiency of delta-1-pyrroline-5-carboxylate dehydrogenase. Pathogenic variants in the ALDH4A1 gene are responsible for this disorder. We here describe an 11-month-old infant with recurrent seizures refractory to multiple antiepileptic drugs. She was hospitalized in view of acute-onset encephalopathy, exacerbation of generalized seizures following an upper respiratory infection. Laboratory investigation revealed significantly elevated proline levels in dried blood spots. DNA sample of the child was subjected to a targeted next-generation sequencing gene panel for hyperprolinemias. We detected a novel nonsense homozygous variant in the ALDH4A1 gene in the child and the heterozygous variant of the same in both the parents. Based on the location of the variant i.e. in the last exon, truncated protein is expected to be expressed by skipping nonsense-mediated decay and such point-nonsense variants could be an ideal target for readthrough drugs to correct genetic defects., (© 2021. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.)
- Published
- 2021
- Full Text
- View/download PDF
3. Clinical profile, aetiology, short-term outcome and predictors of poor outcome of neonatal seizures among out-born neonates admitted to a neonatal unit in Paediatric emergency of a tertiary care hospital in North India: A prospective observational study.
- Author
-
Garg A, Suthar R, Sundaram V, Kumar P, and Angurana SK
- Subjects
- Brain diagnostic imaging, Electroencephalography, Hospitalization statistics & numerical data, Humans, Hypocalcemia complications, Hypocalcemia epidemiology, Infant, Newborn, Infant, Newborn, Diseases diagnosis, Infant, Newborn, Diseases epidemiology, Infant, Newborn, Diseases etiology, Intensive Care Units, Neonatal, Meningitis epidemiology, Neuroimaging, Prospective Studies, Seizures diagnosis, Seizures etiology, Tertiary Care Centers, Epilepsy epidemiology, Seizures epidemiology
- Abstract
Neonatal seizures are common manifestations of several neurological or systemic disorders and associated with high morbidity, mortality and poor short- and long-term developmental outcomes. It is important to determine the aetiology and factors that determine the poor outcome, more so in a newly developed setting. The early detection of predictors of poor outcome will help in planning acute management, counselling, follow-up and rehabilitation services. In this prospective observational study, we looked at the clinical profile, aetiology, short-term outcomes and predictors of poor outcome of neonatal seizures among out-born neonates. The common causes were hypoxic ischaemic encephalopathy, sepsis and metabolic disturbances. One-third of neonates had poor outcome. Abnormal neurological and cardiorespiratory examination at admission; low oxygen saturation, glucose and pH; and hypoxic ischemic encephalopathy-III were predictors of poor outcome.
- Published
- 2021
- Full Text
- View/download PDF
4. Long-term epilepsy control, motor function, cognition, sleep and quality of life in children with West syndrome.
- Author
-
Bhanudeep S, Madaan P, Sankhyan N, Saini L, Malhi P, Suthar R, Saini AG, Ahuja CK, Vyas S, Singh P, Kaur A, Singh G, Sharma R, Negi S, Jayashree M, Attri SV, Singhi P, and Sahu JK
- Subjects
- Adolescent, Child, Child, Preschool, Cognition, Cross-Sectional Studies, Female, Humans, Male, Quality of Life, Retrospective Studies, Sleep, Epilepsy complications, Spasms, Infantile complications
- Abstract
Purpose: To assess epilepsy, motor function, cognitive, sleep, and quality of life outcomes and their predictors in a follow-up cohort with West syndrome (WS) at ≥5 years of age., Methods: Cross-sectional evaluation in a follow-up cohort of WS (aged 5-14 years), between July 2018 and December 2019, was performed at a tertiary-care referral center in Northern India. 164 children were assessed in-person for epilepsy severity, functional status (gross motor and hand function), social quotient, behavioral comorbidities, sleep problems, and quality of life (QoL) using Early Childhood Epilepsy Severity Scale, Gross Motor Function Classification System, Manual Ability Classification System, Vineland Social Maturity Scale, Diagnostic and Statistical Manual of Mental disorders-5 criteria, Children's Sleep Habits Questionnaire, and PedsQL-Epilepsy module respectively. Furthermore, 238 children with the inability to visit the hospital were assessed through telephonic interview along with retrospective case record review for epilepsy control, gross and fine motor measures., Results: 402 children with WS (75 % boys) with regular follow-up were studied and the majority (80 %) had underlying structural etiology. The median age (interquartile range) of the cohort was 92 (78-107) months. Of these, 60 % had evolved to Lennox-Gastaut syndrome (LGS). The following long-term outcomes were observed: ongoing epilepsy (261/402), unfavorable motor status (130/402), moderate to profound intellectual disability (111/164), autistic spectrum disorder (42/164), attention-deficit hyperactivity disorder (18/164), poor sleep (135/164), and impaired QoL (115/164). Non-structural etiology (odds ratio [OR] = 3.8, 95 % confidence interval [CI]: 2.1-5.5, p=<0·0001) and older age (>5 months) at the onset of epileptic spasms (OR = 2·9, 95 % CI: 1.5-5.0, p=<0·0001) were associated with enduring seizure freedom for more than two years., Conclusion: The present study revealed a preponderance of structural etiology and a high rate of transition to LGS. Early age at onset of spasms (before five months) and structural etiology were the predictors of unfavorable long-term epilepsy outcome. QoL was impaired in more than two-thirds of patients and it correlated significantly with cognitive, sleep, motor, and behavioral outcomes. However, the results of our study should be interpreted in the context of significant attrition of the original cohort., (Copyright © 2021 Elsevier B.V. All rights reserved.)
- Published
- 2021
- Full Text
- View/download PDF
5. Effect of early withdrawal of phenobarbitone on the recurrence of neonatal seizures: An open-label randomized controlled trial.
- Author
-
Jindal A, Angurana SK, Suthar R, Kumar P, and Sundaram V
- Subjects
- Anticonvulsants therapeutic use, Child, Humans, India, Infant, Newborn, Seizures drug therapy, Epilepsy drug therapy, Phenobarbital therapeutic use
- Abstract
Background: The long-term administration of phenobarbitone in neonates may be associated with adverse neurological outcome. The timing of stopping phenobarbitone maintenance after acute seizure control in neonates is a matter of debate., Objectives: To study the effect of early withdrawal of phenobarbitone on recurrence of neonatal seizures., Study Design: Open-label randomized controlled trial., Participants: Outborn neonates (≥34 weeks of gestation to <28 days of postnatal period) with seizures (n = 221) admitted to Neonatal unit in Pediatric emergency of a tertiary care hospital in north India over 1 year., Intervention: After a loading dose of phenobarbitone (20 mg/kg), neonates who remained seizure free for at least 12 h were enrolled after written informed consent from parents, and randomized (computer generated block randomization) to 'phenobarbitone withdrawal group' (n = 112) where phenobarbitone maintenance was stopped and 'phenobarbitone continued group' (n = 109) where phenobarbitone maintenance was continued until discharge and further as per clinician's discretion., Outcomes: The primary outcome was seizure recurrence until discharge and secondary outcomes were time to reach full enteral feeds, duration of hospital stay, abnormal neurological status at discharge, and mortality in two groups., Results: The baseline variables were comparable in 2 groups. The incidence of seizure recurrence was similar in the phenobarbitone withdrawal and phenobarbitone continued groups (50% vs. 37.6%, respectively, p = 0.078). Among secondary outcomes, the phenobarbitone withdrawal and continued groups had similar time to reach full enteral feeds (4.02 days vs. 4.2 days, p = 0.75), duration of hospital stay (6.3 days vs. 6.5 days, p = 0.23), abnormal neurological status at discharge (45.6% vs. 38%, p = 0.39), and mortality (11.6% vs. 8.3%, p = 0.50)., Conclusion: Early withdrawal of phenobarbitone in neonatal seizures does not lead to a significant increase in the rate of seizure recurrence., Competing Interests: Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2021 Elsevier Inc. All rights reserved.)
- Published
- 2021
- Full Text
- View/download PDF
6. A prospective cohort study to assess the frequency and risk factors for calcification in single lesion parenchymal neurocysticercosis.
- Author
-
Suthar R, Sahu JK, Ahuja CK, Khandelwal N, Sehgal R, and Singhi P
- Subjects
- Adolescent, Brain physiopathology, Calcinosis complications, Calcinosis drug therapy, Child, Epilepsy complications, Female, Humans, Male, Neurocysticercosis complications, Neurocysticercosis physiopathology, Prospective Studies, Seizures complications, Anticonvulsants therapeutic use, Brain pathology, Epilepsy drug therapy, Neurocysticercosis drug therapy, Seizures drug therapy
- Abstract
Background: Calcified neurocysticercosis (NCC) predisposes patients to an enduring state of epilepsy. The predictors for calcification in parenchymal neurocysticercosis are not well defined., Method: In this prospective cohort study, consecutive children with single-lesion parenchymal NCC were enrolled and followed up for one year. All patients were investigated with brain 3 T-MRI and electroimmunotransfer blot (EITB). Clinical follow-ups were performed every 3 months. Radiology was repeated at the 6-month and one-year follow-ups. The proportion of calcified lesions at one year and the predictors of calcification were studied., Result: During the study period from June 2013 to December 2015, 93 children with single lesion parenchymal NCC were enrolled. At presentation, 90 % of the lesions were in the colloidal stage, and 71 % of the lesions had moderate to severe perilesional oedema. All children had 6 months of follow-up, and 86 (92.5 %) had one year of follow-up. Seizure recurrence was present in 13 (14 %) children. Follow-up radiology at one year showed lesion resolution in 51 (59 %) lesions and calcification in 28 (32.5 %) lesions. Children with calcified lesions during follow-up had a higher odds of seizure recurrences {OR, 95 % CI 3.6(2.3-5.6)}. The presence at baseline of diffusion restriction {OR, 95% CI 2.9 (1.01-8.8)}, scolex or wall calcification in the T2 Star weighted angiography MRI images {OR, 95% CI 3.7 (1.7-8.2)} and >10 mm size of the lesion {OR, 95 % CI 2.4 (1.2-5.01)} predicted lesion calcification., Conclusion: Children with calcification of the parenchymal NCC lesions have a higher risk for seizure recurrence during follow-up. The presence of diffusion restriction, calcified nidus in the colloidal nodular stage, and >10 mm size of the lesion at baseline predicted calcification of the lesion during follow-up., (Copyright © 2020 British Epilepsy Association. Published by Elsevier Ltd. All rights reserved.)
- Published
- 2020
- Full Text
- View/download PDF
7. Calcified neurocysticercosis: The calcified dot is not so innocuous!
- Author
-
Sharawat IK and Suthar R
- Subjects
- Humans, Seizures, Epilepsy, Neurocysticercosis, Tuberculoma
- Abstract
Competing Interests: Declaration of Competing Interest The authors have no conflict of interest to disclose with regard to this article.
- Published
- 2020
- Full Text
- View/download PDF
8. Obstructive Hydrocephalus in Pyridoxine-Dependent Epilepsy: An Uncommon Complication.
- Author
-
Suthar R, Saini SS, Sahu JK, and Singhi P
- Subjects
- Humans, Epilepsy, Hydrocephalus
- Published
- 2017
- Full Text
- View/download PDF
9. The profile of epilepsy and its characteristics in children with neurocutaneous syndromes.
- Author
-
Saini, Lokesh, Mukherjee, Swetlana, Gunasekaran, Pradeep Kumar, Saini, Arushi Gahlot, Ahuja, Chirag, Sharawat, Indar Kumar, Sharma, Rajni, Bhati, Ankita, Suthar, Renu, Sahu, Jitendra Kumar, and Sankhyan, Naveen
- Subjects
EPILEPSY ,SYNDROMES in children ,TUBEROUS sclerosis ,CHILDREN with epilepsy ,CHILDHOOD epilepsy ,SEIZURES (Medicine) - Abstract
Objectives: The profile of seizures in neurocutaneous syndromes is variable. We aimed to define the characteristics of epilepsy in children with neurocutaneous syndromes. Materials and Methods: Cross-sectional study over 18 months at a tertiary care pediatric hospital, including children with neurocutaneous syndromes aged between 1 and 15 years, using the 2017-International League Against Epilepsy classification. Results: In 119 children with neurocutaneous syndromes, 94 (79%) had epilepsy. In eight children with neurofibromatosis one with epilepsy, 5 (62.5%) had generalized motor tonic-clonic seizures, 1 (12.5%) had generalized motor epileptic spasms, 1 (12.5%) had generalized motor automatism, and 1 (12.5%) had a focal seizure. In 69 children with tuberous sclerosis complex with epilepsy, 30 (43.5%) had generalized motor epileptic spasms, 23 (33.3%) had focal seizures, and nine (13.0%) had generalized motor tonic-clonic seizures. In 14 children with Sturge-Weber syndrome with epilepsy, 13 (92.8%) had focal seizures, and 1 (7.2%) had generalized motor tonic seizures. Statistically significant associations were found between epilepsy and intellectual disability (P = 0.02) and behavioral problems (P = 0.00). Conclusion: Profiling seizures in children with neurocutaneous syndromes are paramount in devising target-specific treatments as the epileptogenesis in each syndrome differs in the molecular pathways leading to the hyperexcitability state. Further multicentric studies are required to unravel better insights into the epilepsy profile of neurocutaneous syndromes. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
10. Epilepsy outcomes and hippocampal volumes in children with multiple parenchymal neurocysticercoses
- Author
-
Siddegowda, Shrimanth, Suthar, Renu, Singhi, Pratibha, Ahuja, Chirag, Khandelwal, Niranjan, and Sankhyan, Naveen
- Subjects
NCC Group ,Computer software industry ,Children ,Epilepsy ,Health - Abstract
Byline: Shrimanth. Siddegowda, Renu. Suthar, Pratibha. Singhi, Chirag. Ahuja, Niranjan. Khandelwal, Naveen. Sankhyan Background: We aimed to study the radiological and epilepsy outcomes of children with multiple neurocysticercosis (NCC) and [...]
- Published
- 2021
11. Neurodevelopmental Outcomes of a Cohort of Children with Tuberous Sclerosis Complex with Epileptic Spasms.
- Author
-
Saini, Lokesh, Mukherjee, Swetlana, Gunasekaran, Pradeep Kumar, Malhi, Prahbhjot, Saini, Arushi Gahlot, Sharma, Rajni, Sharawat, Indar Kumar, Suthar, Renu, Sahu, Jitendra Kumar, and Sankhyan, Naveen
- Subjects
TUBEROUS sclerosis ,EPILEPSY ,SPASMS ,ATTENTION-deficit hyperactivity disorder ,PEOPLE with epilepsy ,SEIZURES (Medicine) - Abstract
The neurodevelopmental outcomes in children with tuberous sclerosis complex (TSC) with epileptic spasms remain underdiagnosed and might be responsible for significant morbidity and mortality burdens, even after spasms abate. The study was a cross-sectional study over 18 months at a tertiary care pediatric hospital, involving 30 children with TSC who had epileptic spasms. They were assessed with Diagnostic and Statistical Manual of Mental Disorders-5 criteria for autism spectrum disorder (ASD), attention deficit hyperactivity disorder (ADHD), and intellectual disability (ID), and childhood psychopathology measurement schedule (CPMS) for behavioral disorders. The median age at onset of epileptic spasms was 6.5 (1–12) months, and the age at enrolment was 5 (1–15) years. Of 30 children, 2 (6.7%) had only ADHD, 15 (50%) had only ID/GDD (global developmental delay), 4 (13.3%) had ASD and ID/GDD, 3 (10%) had ADHD and ID/GDD, and 6 (20%) had none. The median intelligence quotient/development quotient (IQ/DQ) score was 60.5 (20–105). CPMS assessment revealed significant behavioral abnormalities in almost half the children. Eight (26.7%) patients were completely seizure-free for at least 2 years, 8 (26.7%) had generalized tonic-clonic seizures, 11 (36.6%) had focal epilepsy, and 3 (10%) had evolved into Lennox-Gastaut syndrome. A high proportion of neurodevelopment disorders, including ASD, ADHD, ID/GDD, and behavioral disorders were seen in this pilot study with a small cohort of children with TSC with epileptic spasms. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
12. Neurocysticercosis
- Author
-
Singhi, Pratibha and Suthar, Renu
- Published
- 2015
- Full Text
- View/download PDF
13. Pyridoxine trial in early infantile epileptic encephalopathy: Never forget!
- Author
-
Sharawat, Indar, Suthar, Renu, Saini, Arushi, and Sankhyan, Naveen
- Subjects
- *
DIAGNOSIS of epilepsy , *BRAIN , *CEREBROSPINAL fluid , *ELECTROENCEPHALOGRAPHY , *EPILEPSY , *MAGNETIC resonance imaging , *ORAL drug administration , *PATIENT monitoring , *VITAMIN B6 , *CEREBRAL anoxia-ischemia , *CHRONIC traumatic encephalopathy , *OPSOCLONUS-Myoclonus syndrome - Abstract
The article present a case study of a 75-day-old male infant with complaints of seizures. It mentions that his cerebrospinal fluid (CSF) examination, sepsis screen, electrolytes, and magnetic resonance imaging (MRI) of the brain were normal. It also mentions that a possibility of early myoclonic encephalopathy (EME) secondary to genetic or metabolic etiology was considered.
- Published
- 2020
- Full Text
- View/download PDF
14. Long-term Cognitive Outcome of Children With Parenchymal Neurocysticercosis: A Prospective Observation Study.
- Author
-
Singhi, Pratibha, Malhi, Prabhjot, Suthar, Renu, Deo, Brijendra, and Khandelwal, N. K.
- Subjects
NEUROCYSTICERCOSIS ,CHILDHOOD epilepsy ,CHILDREN'S health ,COGNITION disorders in children ,PATIENTS ,THERAPEUTICS - Abstract
To study the cognitive profile and scholastic performance of children with parenchymal neurocysticercosis. A total of 500 children with a diagnosis of neurocysticercosis and epilepsy registered in our pediatric neurocysticercosis clinic between January 1996 and December 2002 were enrolled. Patients were evaluated for their scholastic performance using their school grades. Cognitive assessment was done using Parental interview and the “Draw-a-Man” test. Poor scholastic performance was seen in 22.2% (111) children. Draw-a-Man test was done in 148 children; 18.2% (27/148) had scores equivalent to IQ <70. Intermittent headache, behavior problems, and poor memory were reported in 40% (201) children. Multiple lesions, lower socioeconomic status, and calcified lesions on follow-up were associated with academic underachievement (P < .05). About a fourth of children with neurocysticercosis had cognitive impairment during follow-up. This was mostly seen in children from lower socioeconomic status and in those with multiple-lesion neurocysticercosis. [ABSTRACT FROM AUTHOR]
- Published
- 2018
- Full Text
- View/download PDF
15. Hyperhomocysteinaemia in children receiving phenytoin and carbamazepine monotherapy: a cross-sectional observational study.
- Author
-
Chandrasekaran, Saravanan, Patil, Sooraj, Suthar, Renu, Attri, Savita Verma, Sahu, Jitendra Kumar, Sankhyan, Naveen, Tageja, Mini, and Singhi, Pratibha
- Subjects
TREATMENT of hyperhomocysteinemia ,PHENYTOIN ,JUVENILE diseases ,CARBAMAZEPINE ,CROSS-sectional method ,THERAPEUTICS ,THERAPEUTIC use of folic acid ,VITAMIN B complex ,ANTICONVULSANTS ,EPILEPSY ,LONG-term health care ,CASE-control method ,HYPERHOMOCYSTEINEMIA ,VITAMIN therapy - Abstract
Objective: Long-term therapy with phenytoin and carbamazepine is known to cause hyperhomocysteinaemia. We evaluated the prevalence of hyperhomocysteinaemia in North Indian children receiving phenytoin or carbamazepine monotherapy for >6 months duration and the effect of folic acid supplementation on plasma homocysteine.Methods: In this cross-sectional observational study we enrolled consecutive children aged 2-12 years with epilepsy who had received phenytoin or carbamazepine monotherapy for >6 months. Plasma total homocysteine, folic acid, vitamin B12 and antiepileptic drug concentrations were measured. Healthy age- and sex-matched controls were recruited. Children with homocysteine >10.4 µmol/L received folic acid supplementation for 1 month and homocysteine and folic acid concentrations were measured after 1 month follow-up.Results: A total of 112 children receiving antiepileptic monotherapy for >6 months were enrolled. Hyperhomocysteinaemia was present in 54 children (90%) receiving phenytoin, 45 children (90%) receiving carbamazepine therapy and 17 (34%) controls (p<0.05). Mean plasma homocysteine concentrations were significantly higher (18.9±10.2 vs 9.1±3 µmol/L) and serum folic acid concentrations (10.04±8.5 ng/ml vs 12.6±4.8 p<0.001) and vitamin B12 concentrations (365±155 pg/mL vs 474±332 pg/mL, p=0.02) were significantly lower in the study group compared with the control group. Duration of antiepileptic drug therapy correlated significantly with elevated homocysteine and reduced folic acid concentrations (p<0.05). Supplementation with folic acid for 1 month led to a reduction in plasma homocysteine concentrations in the study group (from 20.9±10.3 µmol/L to 14.2±8.2 µmol/L, p<0.05).Conclusions: Phenytoin or carbamazepine monotherapy for >6 months duration is associated with hyperhomocysteinaemia in 90% of North Indian children. Elevated homocysteine concentrations were normalised in these children with folic acid supplementation. [ABSTRACT FROM AUTHOR]- Published
- 2017
- Full Text
- View/download PDF
16. Low Lesion Clearance Rates in Neurocysticercosis: Is It Time to Review Guidelines?
- Author
-
Barman, Prabal, Sankhyan, Naveen, Suthar, Renu, Vyas, Sameer, Saini, Lokesh, Saini, Arushi, and Sahu, Jitendra K
- Subjects
- *
MAGNETIC resonance imaging , *NEUROCYSTICERCOSIS , *COMPUTED tomography , *DISEASE remission , *TAENIA - Abstract
The standard treatment guidelines of neurocysticercosis have been described as per computed tomography (CT)–based studies. We aimed to prospectively study if posttreatment magnetic resonance imaging (MRI) clearance rates of neurocysticercosis were like those reported in literature using CT.A prospective observational study in newly diagnosed children with neurocysticercosis was undertaken. Children were treated with antihelminthics and steroids and followed up after 6 months. The primary objective was to study the proportion of children with single-lesion neurocysticercosis who were in radiologic resolution at 6 months and clinical remission (seizure-free for the preceding 3 months).Eighty of 128 consecutive children screened were included (single lesion, 65; multiple lesions, 15). Seventy-two children were evaluated at 6 months. Seizure recurrence was seen in 5 (6.2%). Brain MRI showed an overall clearance of lesions in 10 (14%) children. In the children with single-lesion neurocysticercosis (65), 59 were followed up at 6 months, and lesions resolved in 9 (15.3%, 95% confidence interval of 6.1-24.4).In children with single-lesion neurocysticercosis treated with antihelminthics and corticosteroids, the lesion resolution rate is only 15% at 6 months. Thus, there is a need to review old recommendations and use MRI as a standard outcome measure. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
17. Progressive Head Enlargement in a Child With Motor Delay.
- Author
-
Sharawat, Indar Kumar and Suthar, Renu
- Subjects
- *
LEUKODYSTROPHY , *HEAD , *GENETIC disorder diagnosis , *GENETIC disorders , *MAGNETIC resonance imaging , *NEURODEGENERATION , *CRANIOFACIAL abnormalities , *DISEASE complications - Published
- 2019
- Full Text
- View/download PDF
18. Rhythmic Head Nodding With Absence Seizures.
- Author
-
Singanamalla, Bhanudeep and Suthar, Renu
- Subjects
- *
SEIZURES (Medicine) , *CHILDHOOD epilepsy , *DIAGNOSIS of epilepsy , *ELECTROENCEPHALOGRAPHY , *EPILEPSY , *PETIT mal epilepsy , *VIDEO recording , *BODY movement - Abstract
Keywords: Epilepsy; Myoclonic absence; Hyperventilation; Electroencephalography; Valproate Epilepsy with myoclonic absences[1] refers to absence epilepsy with rhythmic 3 Hz myoclonic movements, which are associated with 3 Hz generalized spike-wave discharges on the EEG. Epilepsy with myoclonic absences is considered a pharmacoresistant epilepsy, but the combination of valproate and ethosuximide has yielded good results. [Extracted from the article]
- Published
- 2020
- Full Text
- View/download PDF
19. Diaper Rash in an Infant with Seizures.
- Author
-
Dhawan, Sumeet R., Sharawat, Indar Kumar, Saini, Arushi Gahlot, Suthar, Renu, and Attri, Savita Verma
- Published
- 2019
- Full Text
- View/download PDF
Catalog
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.