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Start Over Author "Scott, Neil W." Topic eortc qlq-c30
5 results on '"Scott, Neil W."'

4. Replication and validation of higher order models demonstrated that a summary score for the EORTC QLQ-C30 is robust

Author

Giesinger, Johannes M., Kieffer, Jacobien M., Fayers, Peter M., Groenvold, Mogens, Petersen, Morten Aa., Scott, Neil W., Sprangers, Mirjam A.G., Velikova, Galina, Aaronson, Neil K., Klinische Psychologie (Psychologie, FMG), CCA -Cancer Center Amsterdam, APH - Amsterdam Public Health, and Medical Psychology

Subjects
Questionnaires, Higher order factor scores, Epidemiology, Measurement model, Health-related quality of life, otorhinolaryngologic diseases, EORTC QLQ-C30, social sciences, Confirmatory factor analysis, humanities
Abstract

Objective: To further evaluate the higher order measurement structure of the European Organisation for Research and Treatment of Cancer (EORTC) Quality of Life Questionnaire Core 30 (QLQ-C30), with the aim of generating a summary score. Study Design and Setting: Using pretreatment QLQ-C30 data (N = 3,282), we conducted confirmatory factor analyses to test seven previously evaluated higher order models. We compared the summary score(s) derived from the best performing higher order model with the original QLQ-C30 scale scores, using tumor stage, performance status, and change over time (N = 244) as grouping variables. Results: Although all models showed acceptable fit, we continued in the interest of parsimony with known-groups validity and responsiveness analyses using a summary score derived from the single higher order factor model. The validity and responsiveness of this QLQ-C30 summary score was equal to, and in many cases superior to the original, underlying QLQ-C30 scale scores. Conclusion: Our results provide empirical support for a measurement model for the QLQ-C30 yielding a single summary score. The availability of this summary score can avoid problems with potential type I errors that arise because of multiple testing when making comparisons based on the 15 outcomes generated by this questionnaire and may reduce sample size requirements for health-related quality of life studies using the QLQ-C30 questionnaire when an overall summary score is a relevant primary outcome.

Published
2016

5. The relationship between overall quality of life and its subdimensions was influenced by culture: analysis of an international database

Author

Scott, Neil W., Fayers, Peter M., Aaronson, Neil K., Bottomley, Andrew, de Graeff, Alexander, Groenvold, Mogens, Koller, Michael, Petersen, Morten A., and Sprangers, Mirjam A.G.

Subjects
*QUALITY of life, *DATABASES, *MEDICAL care, *REGRESSION analysis
Abstract

Abstract: Objective: To investigate whether geographic and cultural factors influence the relationship between the global health status quality of life (QL) scale score of the European Organisation for Research and Treatment of Cancer QLQ-C30 questionnaire and seven other subscales representing fatigue, pain, physical, role, emotional, cognitive, and social functioning. Study Design and Setting: A large international database of QLQ-C30 responses was assembled. A linear regression model was developed predicting the QL scale score and including interactions between geographical/cultural groupings and the seven other scale scores. Results: The pain subscale appeared to have relatively greater influence and fatigue relatively lower influence for those from other European regions compared with respondents from the UK when predicting overall quality of life (QoL). For Scandinavia physical functioning appeared to contribute relatively less. There was evidence of greater emphasis on cognitive functioning for those from South Asia and Latin America compared with the UK, whereas for those from Islamic countries, the role functioning scale appeared to have less influence and physical and social functioning more influence. Conclusion: These results provide evidence that different cultural groups may emphasize different aspects of their QoL. This has implications for studies using QoL questionnaires in international comparisons. [Copyright &y& Elsevier]

Published
2008
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