1. Kenji Soda--researching enzymes with the spirit of an alpinist.
- Author
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Yoshimura T, Mihara H, Ohshima T, and Tanizawa K
- Subjects
- Amino Acids chemistry, Amino Acids metabolism, Bacteria enzymology, Bacterial Proteins chemistry, Bacterial Proteins metabolism, Flavin-Adenine Dinucleotide chemistry, Flavin-Adenine Dinucleotide metabolism, Humans, Molecular Structure, NADP chemistry, NADP metabolism, Pyridoxal Phosphate chemistry, Pyridoxal Phosphate metabolism, Selenium chemistry, Selenium metabolism, Sulfur chemistry, Sulfur metabolism, Enzymes chemistry, Enzymes metabolism, Mountaineering
- Abstract
Like an alpinist continuously seeking virgin peaks to climb, Kenji Soda has investigated a variety of unique enzymes for which there was little or no information available; and by doing so he opened up a variety of new fields in enzyme science and technology. In particular, he has promoted the study of enzymes requiring vitamin B-derived cofactors such as FAD, NAD(P) and pyridoxal 5'-phosphate, shedding light on their reaction mechanisms, enzymological properties, crystal structures and potential practical applications. Highlighted in this review are the studies of enzymes acting on d-amino acids and sulphur/selenium-containing amino acids and those from thermophilic and psychrophilic bacteria.
- Published
- 2010
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