This review analyzes papers presented at the "Second International Kosygin Readings: Energy- and Resource-Efficient Environmentally Safe Technologies and Equipment," an International Scientific and Technical Symposium Celebrating the 100th Anniversary of the Kosygin State University of Russia, which was held as part of the International Kosygin Forum. These papers consider the fundamental principles of methods for intensifying basic processes in various industrial technologies, the scientific fundamentals of the development of energy- and resource-efficient chemical and other processes, innovative developments in this field, issues of the environmental safety of technological processes and equipment, effective systems for increasing technosphere safety, the theory and calculation of heat and mass transfer processes in technosphere protection systems, the issues of digitization as an intellectual and technological factor for increasing the energy and resource efficiency of chemical-manufacturing processes and plants, and the results of studies aimed at developing the theoretical fundamentals of energy- and resource-efficient industrial machinery and equipment. [ABSTRACT FROM AUTHOR]