10 results on '"Miyashita, Yusuke"'
Search Results
2. Three-Year Clinical Outcomes of the Innova™ Self-Expanding Nitinol Stent for the Treatment of Femoropopliteal Lesions
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Karashima, Eiji, Takahara, Mitsuyoshi, Hozawa, Koji, Yamauchi, Yasutaka, Suzuki, Kenji, Suematsu, Nobuhiro, Miyashita, Yusuke, Enomoto, Soichiro, Tokuyama, Hideo, Murata, Naotaka, Haraguchi, Kazuki, and Soga, Yoshimitsu
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- 2021
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3. Efficacy of statin treatment after endovascular therapy for isolated below-the-knee disease in patients with critical limb ischemia
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Tomoi, Yusuke, Soga, Yoshimitsu, Iida, Osamu, Hirano, Keisuke, Suzuki, Kenji, Kawasaki, Daizo, Yamauchi, Yasutaka, Miyashita, Yusuke, Tazaki, Junichi, and Nobuyoshi, Masakiyo
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- 2013
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4. Impact of Diabetes Mellitus on Critical Limb Ischemia With Below the Knee Disease: Japan Below-the-Knee Artery Treatment Subanalysis.
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Suzuki, Kenji, Iida, Osamu, Yamauchi, Yasutaka, Nakano, Masatsugu, Soga, Yoshimitsu, Kawasaki, Daizo, Tazaki, Junichi, Yamaoka, Terutoshi, Suematsu, Nobuhiro, Shintani, Yoshiaki, Miyashita, Yusuke, Inoue, Naoto, and Meguro, Taiichiro
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DIABETES complications ,AMPUTATION ,ENDOVASCULAR surgery ,ISCHEMIA ,LEG ,LIMB salvage ,MULTIVARIATE analysis ,PERIPHERAL vascular diseases ,SURVIVAL ,ACTIVITIES of daily living ,DESCRIPTIVE statistics - Abstract
Background: A strong association exists between diabetes mellitus and critical limb ischemia. Methods and Results: We performed endovascular therapy on 1060 limbs in 884 patients with below knee lesions only. The patients were divided into diabetes (DG) and nondiabetes groups (NDG). Limb salvage was poorer in the DG (79% vs 89%, P =.0061). No significant difference was observed in mortality, amputation-free survival (AFS), and target vessel revascularization (TVR). Multivariate analysis revealed diabetes status, infection, poor activity of daily living (ADL), younger age, and procedure failure as independent predictors of major amputation in DG. In the NDG, procedure failure was the predictor, and younger age and poor ADL showed tendency of major amputation. Conclusions: Mortality, AFS, and TVR showed no significant difference between the 2 groups, but major amputation was more frequent in DG. Not only revascularization but also infection and diabetes control were very important for limb salvage in DG. [ABSTRACT FROM AUTHOR]
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- 2020
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5. A Case of Rapid Progressive Kidney Dysfunction with Severely Calcified Stenotic Aorta.
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Harada, Makoto, Miyashita, Yusuke, Ichikawa, Tohru, and Kobayashi, Mamoru
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ATHEROSCLEROTIC plaque , *CALCIFICATION , *AORTIC stenosis , *RENAL cell carcinoma , *KIDNEY failure - Abstract
Coral reef aorta is rare type of atherosclerotic diseases with severe calcification in the visceral part of the aorta. We present a case of coral reef aorta with severe abdominal aortic stenosis in a 67-year-old man. The patient presented with hypertension, claudication, and rapid progression of renal dysfunction over several months. Angiography revealed a severely stenotic suprarenal abdominal aorta resulting in renal ischemia and dysfunction. In addition, his right kidney was completely atrophied. After open surgical repair of the stenotic aorta including renal artery reconstruction, renal function did not improve. There was stenotic anastomosis to the renal artery. After endovascular therapy to the stenotic anastomosis, renal function dramatically improved. Stenotic coral reef aorta may be the cause of kidney dysfunction. In addition, surgical complication of stenotic anastomosis may be successfully treated by endovascular therapy. [ABSTRACT FROM AUTHOR]
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- 2018
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6. Inflammatory Cytokine Levels After Endovascular Therapy in Patients With Peripheral Artery Disease.
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Ueki, Yasushi, Miura, Takashi, Miyashita, Yusuke, Ebisawa, Souichiro, Motoki, Hirohiko, Izawa, Atsushi, Koyama, Jun, and Ikeda, Uichi
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VASCULAR surgery ,CYTOKINES ,ENZYME-linked immunosorbent assay ,INFLAMMATION ,INTERLEUKINS ,INTERMITTENT claudication ,LONGITUDINAL method ,PERIPHERAL vascular diseases ,TUMOR necrosis factors - Abstract
We evaluated the impact of endovascular therapy (EVT) on inflammatory cytokine levels and its relationship with in-stent restenosis in patients with peripheral artery disease. The study prospectively enrolled 35 patients with intermittent claudication who underwent EVT of the iliofemoral artery. Levels of interleukin 6 (IL-6), monocyte chemoattractant protein-1 (MCP-1), and tumor necrosis factor α (TNF-α) were measured using enzyme-linked immunosorbent assay before and at 2 hours, 4 hours, and 3 months after EVT. All cytokine levels increased significantly after EVT (IL-6 [pg/mL]: from 1.51 [0.84-1.93] before EVT to 6.97 [4.05-20.41] at 2 hours and 13.29 [4.57-31.88] at 4 hours; MCP-1 [pg/mL]: from 326.65 [265.60-406.55] before EVT to 411.18 [341.21-566.27] at 2 hours and 519.36 [383.58-644.85] at 4 hours; TNF-α [pg/mL]: from 1.08 [0.77-1.29] before EVT to 1.25 [0.94-1.81] at 2 hours and 1.27 [0.95-1.59] at 4 hours, all P < .001). However, cytokine levels did not differ significantly between lesions with and without in-stent restenosis. Overall, our results suggest that EVT significantly increases IL-6, MCP-1, and TNF-α levels in the ischemic leg, but this effect is not associated with a higher rate of in-stent restenosis. [ABSTRACT FROM AUTHOR]
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- 2017
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7. Efficacy and Safety of Endovascular Therapy for Aortoiliac TASC D Lesions.
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Suzuki, Kenji, Mizutani, Yukiko, Soga, Yoshimitsu, Iida, Osamu, Kawasaki, Daizo, Yamauchi, Yasutaka, Hirano, Keisuke, Koshida, Ryouji, Kamoi, Daisuke, Tazaki, Junichi, Higashitani, Michiaki, Shintani, Yoshiaki, Yamaoka, Terutoshi, Okazaki, Shinya, Suematsu, Nobuhiro, Tsuchiya, Taketsugu, Miyashita, Yusuke, Shinozaki, Norihiko, Takahashi, Hiroki, and Inoue, Naoto
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ACADEMIC medical centers ,CARDIOVASCULAR diseases ,CHI-squared test ,REPORTING of diseases ,MULTIVARIATE analysis ,PATIENT safety ,PROBABILITY theory ,SURGICAL complications ,T-test (Statistics) ,SECONDARY analysis ,TREATMENT effectiveness ,PROPORTIONAL hazards models ,DATA analysis software ,DESCRIPTIVE statistics ,KAPLAN-Meier estimator ,LOG-rank test ,MANN Whitney U Test - Abstract
Background: Although there is increasing evidence of the effectiveness of endovascular therapy for complex aortoiliac (AI) occlusive disease, it is not universally applied to TASC D lesions. Methods: A total of 2096 patients, 2601 limbs with AI occlusive disease, were enrolled. The lesions were categorized as TASC D (395) or TASC A-C (2206), and we compared baseline data, procedure, and follow-up result between the 2 groups. Results: The success rate of the procedure was significantly lower in the TASC D group (91.6% vs 99.3%, P < .01), and more procedure complications occurred in the TASC D group (11.1% vs 5.2%, P < .01). The results of a 5-year follow-up revealed no significant difference in primary patency (77.9% vs 77.1%, P = .17) and major adverse cardiovascular and limb events (MACLE; 30.5% vs 33.4%, P = .42) between the 2 groups. A multivariate analysis revealed complications and critical limb ischemia are independent predictors of MACLE in the TASC D group. Conclusion: The success rate of the procedure was lower in the TASC D group. Complications were more frequent in the TASC D group, and they were related to MACLE. [ABSTRACT FROM AUTHOR]
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- 2017
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8. Two-Year Life Expectancy in Patients With Critical Limb Ischemia.
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Soga, Yoshimitsu, Iida, Osamu, Takahaera, Mitsuyoshi, Hirano, Keisuke, Suzuki, Kenji, Kawasaki, Daizo, Miyashita, Yusuke, and Tsuchiya, Taketsugu
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Objectives This study sought to estimate the 2-year life expectancy (2YLE) (estimated survival rate >50% at 2 years) in patients with critical limb ischemia (CLI) using the risk score based on predictors of all-cause mortality within 2 years. Background It has been reported that 2YLE is one of the important factors in the decision making of the revascularization strategy. However, little is known about the probability and the prognostic factors of a 2YLE. Method This study was performed as a multicenter retrospective analysis. Between March 2004 and December 2011, 995 CLI patients with follow-up period >730 days undergoing endovascular therapy (EVT) were identified and analyzed. Results Within 2 years, 412 patients (41%) died, and a cardiovascular cause accounted for 47% of deaths. On multivariate analysis, the independent prognostic factors were age 65 to 79 years (odds ratio [OR]: 1.9), 80 years of age or older (OR: 3.7), body mass index (BMI) 18.0 to 19.9 kg/m 2 (OR: 1.5), BMI <18.0 kg/m 2 (OR: 2.9), nonambulatory status (OR: 2.4), hemodialysis (OR: 2.1), cerebrovascular disease (OR: 1.6), left ventricular ejection fraction (LVEF) of 40% to 49% (OR: 1.8), LVEF <40% (OR: 2.6), Rutherford class 5 (OR: 1.9), and Rutherford class 6 (OR: 3.4). The 2-year survival rate in each risk score was calculated based on each OR (full score: 15 points). After that, 2YLE was estimated based on the survival rate in each risk score, the probability of a 2YLE of ≥8 points indicated a <50% probability of 2-year survival. Conclusions The independent prognostic factors for the 2YLE were age, BMI, nonambulatory status, hemodialysis, cerebrovascular disease, LVEF, and tissue loss. A 2YLE score of ≥8 points indicated a <50% probability of 2-year survival. This score seemed to be helpful for identifying CLI patients with a poor prognosis. [ABSTRACT FROM AUTHOR]
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- 2014
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9. Impact of Angiosome-Oriented Revascularization on Clinical Outcomes in Critical Limb Ischemia Patients Without Concurrent Wound Infection and Diabetes.
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Iida, Osamu, Takahara, Mitsuyoshi, Soga, Yoshimitsu, Yamauchi, Yasutaka, Hirano, Keisuke, Tazaki, Junichi, Yamaoka, Terutoshi, Suematsu, Nobuhiro, Suzuki, Kenji, Shintani, Yoshiaki, Miyashita, Yusuke, and Uematsu, Masaaki
- Abstract
Purpose: To investigate the impact of angiosome-oriented revascularization on clinical outcomes in critical limb ischemia (CLI) patients excluding those with both diabetes and wound infection. Methods: Using a retrospective multicenter database, a propensity score matching analysis was performed of 539 consecutive CLI patients (375 men; mean age 71 ± 11 years) without concurrent wound infection and diabetes who underwent balloon angioplasty of isolated infrapopliteal lesions. Propensity score matching produced 2 groups of 182 patients each who underwent angiosome-oriented direct revascularization (123 men; mean age 72 ± 11 years) or indirect revascularization (125 men; mean age 72 ± 11 years). The groups were compared for wound healing rate, freedom from major adverse limb events (MALE), and amputation-free survival (AFS). Results: In the overall population, indirect revascularization was performed in 36.6% (n=197). In the propensity matching analysis, the complete wound healing rate at 12 months was higher in the direct group than the indirect revascularization patients (75% vs. 64%, p=0.01), while freedom from MALE (p=0.99) and AFS (p=0.17) were not significantly different at up to 24 months. In multivariate analysis, indirect revascularization had an independent negative impact on wound healing (adjusted hazard ratio 0.7, p=0.008). Conclusion: After propensity matching analysis for CLI patients other than those with both diabetes and wound infection, the wound healing rate was higher after direct revascularization than after indirect revascularization, whereas MALE and AFS were not significantly different. [ABSTRACT FROM AUTHOR]
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- 2014
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10. Efficacy of the S.M.A.R.T. Control vs. Other Stents for Aortoiliac Occlusive Disease in Contemporary Clinical Practice.
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Iida, Osamu, Soga, Yoshimitsu, Takahara, Mitsuyoshi, Kawasaki, Daizo, Yamauchi, Yasutaka, Suzuki, Kenji, Hirano, Keisuke, Ryoji, Koshida, Kamoi, Daisuke, Tazaki, Junichi, Higashitani, Michiaki, Shintani, Yoshiaki, Yamaoka, Terutoshi, Okazaki, Shinya, Suematsu, Nobuhiro, Tsuchiya, Taketsugu, Miyashita, Yusuke, Shinozaki, Norihiko, Takahashi, Hiroki, and Uematsu, Masaaki
- Abstract
Purpose: To compare the safety and efficacy of the S.M.A.R.T. Control stent vs. other stents in patients with symptomatic aortoiliac occlusive disease (AIOD) followed for up to 4 years. Methods: A subgroup analysis of data from a retrospective multicenter registry examined 2036 symptomatic patients (1659 men; mean age 71±8 years) who received stent- supported endovascular therapy for 2541 AIOD lesions between April 2005 and December 2009. The cohort was divided into the S.M.A.R.T. stent group (955 patients/ 1196 lesions) and the "other" stent group (1081 patients/1345 lesions). The main study outcomes of primary patency and event-free survival at 4 years were compared before and after propensity matching analysis. The rates for freedom from major amputation, surgical conversion, target lesion revascularization (TLR), and major adverse limb events were also assessed. Results: The S.M.A.R.T. Control stent group had greater frequency of critical limb ischemia (CLI), TASC C/D lesions, and chronic total occlusions. The mean follow-up was 25±17 months in the S.M.A.R.T. group vs. 29±19 months in the other stent group. After propensity matching, 4-year primary patency (86% vs. 76%, p<0.001) and freedom from adverse limb events (93% vs. 90%, IO=0.04) were greater in the S.M.A.R.T. Control stent group, while event-free survival rates (75% vs. 77%, p=0.50) were similar between groups. Univariate subgroup analysis showed that use of the S.M.A.R.T. stent was associated with greater primary patency in patients with renal insufficiency (serum creatinine >1.5 mg/dL) and CLI. Conclusion: After propensity matching analysis, the durability of the S.M.A.R.T. stent was superior to that of other stents, which might reflect differing design characteristics. [ABSTRACT FROM AUTHOR]
- Published
- 2013
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