11 results on '"A. Stavroulis"'
Search Results
2. Reply: Criticizing the effect of ovarian suspension on adhesions in laparoscopic surgery for endometriosis.
- Author
-
Hoo WL, Stavroulis A, Pateman K, Saridogan E, Cutner A, Tong EN, and Jurkovic D
- Subjects
- Female, Humans, Endometriosis surgery, Gynecologic Surgical Procedures methods, Ovary surgery, Tissue Adhesions prevention & control
- Published
- 2014
- Full Text
- View/download PDF
Catalog
3. Does ovarian suspension following laparoscopic surgery for endometriosis reduce postoperative adhesions? An RCT.
- Author
-
Hoo WL, Stavroulis A, Pateman K, Saridogan E, Cutner A, Pandis G, Tong EN, and Jurkovic D
- Subjects
- Double-Blind Method, Female, Humans, Laparoscopy, Ovary diagnostic imaging, Tissue Adhesions epidemiology, Ultrasonography, Endometriosis surgery, Gynecologic Surgical Procedures methods, Ovary surgery, Tissue Adhesions prevention & control
- Abstract
Study Question: Is temporary ovarian suspension following laparoscopic surgery for severe pelvic endometriosis an effective method for reducing the prevalence of postoperative ovarian adhesions?, Summary Answer: Temporary ovarian suspension for 36-48 h following laparoscopic treatment of severe endometriosis does not result in a significant reduction of postoperative ovarian adhesions., What Is Known Already: Pelvic adhesions often develop following laparoscopic surgery for severe pelvic endometriosis. Adhesions can cause chronic pelvic pain and fertility problems compromising the success of treatment. Small observational studies suggested that temporary postoperative ovarian suspension to the abdominal wall may significantly reduce the prevalence of postoperative ovarian adhesions., Study Design, Size, Duration: This was a prospective within group comparison double-blind RCT. We recruited premenopausal women with severe pelvic endometriosis who required extensive laparoscopic surgery with preservation of the uterus and ovaries. Severity of the disease and eligibility for inclusion were determined at surgery. A total of 55 women were randomized to unilateral ovarian suspension for 36-48 h, 52 of which were included in the final analysis. Both ovaries were routinely suspended to the anterior abdominal wall during surgery. At the end of the operation, each woman was randomized to having only one ovary suspended postoperatively. The suture suspending the contralateral ovary was cut and a new transabdominal suture was inserted to act as a placebo. Both sutures were removed 36-48 h after surgery prior to discharge. Three months after surgery, all women attended for a detailed transvaginal ultrasound scan to assess ovarian mobility. Both the women and the ultrasound operators were blinded as to the side of postoperative ovarian suspension. The primary outcome was the prevalence of ovarian adhesions as described on ultrasound examination. Secondary outcomes were the severity of adhesions and the presence and intensity of postoperative pain., Participants/materials, Setting, Methods: All 55 participants had severe pelvic endometriosis confirmed at laparoscopy. As each participant had only one of their ovaries suspended at the end of surgery, they acted as their own control., Main Results and the Role of Chance: The median interval between ovarian suspension and postoperative scan was 99 days (interquartile range 68-114). There was no significant difference (P = 0.23) in the prevalence of postoperative ovarian adhesions between the suspended (20/52) and unsuspended (27/52) side (38.5 versus 51.9%) [odds ratio 0.56 (95% confidence interval 0.22-1.35)]., Limitations, Reasons for Caution: Ovaries were suspended postoperatively for 36-48 h. Longer suspension could result in lower prevalence of postoperative adhesions., Wider Implications of the Findings: The value of temporary ovarian suspension in women having surgery for mild-to-moderate endometriosis should be investigated further. The potential benefits of other adhesion prevention strategies, such as surgical barrier agents, in women undergoing surgical treatment for severe pelvic endometriosis should also be explored., Study Funding/competing Interests: E.S. received honoraria from Ethicon for provision of training to healthcare professionals and consultancy fees from Bayer. W.H. was supported by the research fund provided by the Gynaecology Ultrasound Centre, London UK. A.C. is on the advisory board for surgical innovations for which he receives an annual honorarium. A.C. also received support for courses and education from Storz and Johnson and Johnson and support for clinical nursing from Covidien and Lotus. The other authors declared no competing interests., Trial Registration Number: Current Controlled Trials ISRCTN24242218. more...
- Published
- 2014
- Full Text
- View/download PDF
4. ESHRE guideline: endometriosis
- Author
-
Christian M Becker, Attila Bokor, Oskari Heikinheimo, Andrew Horne, Femke Jansen, Ludwig Kiesel, Kathleen King, Marina Kvaskoff, Annemiek Nap, Katrine Petersen, Ertan Saridogan, Carla Tomassetti, Nehalennia van Hanegem, Nicolas Vulliemoz, Nathalie Vermeulen, Signe Altm??e, Baris Ata, Elizabeth Ball, Fabio Barra, Ercan Bastu, Alexandra Bianco-Anil, Ulla Breth Knudsen, R??ka Brubel, Julia Cambitzi, Astrid Cantineau, Ying Cheong, Angelos Daniilidis, Bianca De Bie, Caterina Exacoustos, Simone Ferrero, Tarek Gelbaya, Josepha Goetz-Collinet, Gernot Hudelist, Munawar Hussain, Tereza Indrielle-Kelly, Shaheen Khazali, Sujata Lalit Kumar, Umberto Leone Roberti Maggiore, Jacques W M Maas, Helen McLaughlin, Jos?? Metello, Velja Mijatovic, Yasaman Miremadi, Charles Muteshi, Michelle Nisolle, Engin Oral, George Pados, Dana Parades, Nicola Pluchino, Prasanna Raj Supramaniam, Maren Schick, Beata Seeber, Renato Seracchioli, Antonio Simone Lagan??, Andreas Stavroulis, Linda Tebache, G??rkan Uncu, Uschi Van den Broeck, Arno van Peperstraten, Attila Vereczkey, Albert Wolthuis, P??nar Yal????n Bahat, Chadi Yazbeck, Christian M Becker, Attila Bokor, Oskari Heikinheimo, Andrew Horne, Femke Jansen, Ludwig Kiesel, Kathleen King, Marina Kvaskoff, Annemiek Nap, Katrine Petersen, Ertan Saridogan, Carla Tomassetti, Nehalennia van Hanegem, Nicolas Vulliemoz, Nathalie Vermeulen, Signe Altm??e, Baris Ata, Elizabeth Ball, Fabio Barra, Ercan Bastu, Alexandra Bianco-Anil, Ulla Breth Knudsen, R??ka Brubel, Julia Cambitzi, Astrid Cantineau, Ying Cheong, Angelos Daniilidi, Bianca De Bie, Caterina Exacousto, Simone Ferrero, Tarek Gelbaya, Josepha Goetz-Collinet, Gernot Hudelist, Munawar Hussain, Tereza Indrielle-Kelly, Shaheen Khazali, Sujata Lalit Kumar, Umberto Leone Roberti Maggiore, Jacques W M Maa, Helen McLaughlin, Jos?? Metello, Velja Mijatovic, Yasaman Miremadi, Charles Muteshi, Michelle Nisolle, Engin Oral, George Pado, Dana Parade, Nicola Pluchino, Prasanna Raj Supramaniam, Maren Schick, Beata Seeber, Renato Seracchioli, Antonio Simone Lagan??, Andreas Stavrouli, Linda Tebache, G??rkan Uncu, Uschi Van den Broeck, Arno van Peperstraten, Attila Vereczkey, Albert Wolthui, P??nar Yal????n Bahat, Chadi Yazbeck, University of Helsinki, Clinicum, Department of Obstetrics and Gynecology, and HUS Gynecology and Obstetrics more...
- Subjects
endometriosis ,LAPAROSCOPIC EXCISION ,OVARIAN-CANCER ,surgery ,3123 Gynaecology and paediatrics ,ASSISTED REPRODUCTIVE TECHNOLOGY ,ADD-BACK THERAPY ,TERM-FOLLOW-UP ,CONSERVATIVE SURGERY ,fertility ,Reproductive Biology ,Science & Technology ,ESHRE guideline ,HORMONE AGONIST ,Other Research Radboud Institute for Health Sciences [Radboudumc 0] ,endometriosi ,Obstetrics & Gynecology ,pelvic pain ,General Medicine ,BIMANUAL PELVIC EXAMINATION ,adolescent ,CYCLIC ORAL-CONTRACEPTIVES ,INTRAUTERINE SYSTEM ,Life Sciences & Biomedicine ,guideline - Abstract
Main results and the role of chance: This guideline aims to help clinicians to apply best care for women with endometriosis. Although studies mostly focus on women of reproductive age, the guideline also addresses endometriosis in adolescents and postmenopausal women. The guideline outlines the diagnostic process for endometriosis, which challenges laparoscopy and histology as gold standard diagnostic tests. The options for treatment of endometriosis-associated pain symptoms include analgesics, medical treatments and surgery. Non-pharmacological treatments are also discussed. For management of endometriosis-associated infertility, surgical treatment and/or medically assisted reproduction are feasible. While most of the more recent studies confirm previous ESHRE recommendations, there are five topics in which significant changes to recommendations were required and changes in clinical practice are to be expected. Limitations reasons for caution: The guideline describes different management options but, based on existing evidence, no firm recommendations could be formulated on the most appropriate treatments. Also, for specific clinical issues, such as asymptomatic endometriosis or extrapelvic endometriosis, the evidence is too scarce to make evidence-based recommendations. Wider implications of the findings: The guideline provides clinicians with clear advice on best practice in endometriosis care, based on the best evidence currently available. In addition, a list of research recommendations is provided to stimulate further studies in endometriosis. Study question: How should endometriosis be diagnosed and managed based on the best available evidence from published literature? Summary answer: The current guideline provides 109 recommendations on diagnosis, treatments for pain and infertility, management of disease recurrence, asymptomatic or extrapelvic disease, endometriosis in adolescents and postmenopausal women, prevention and the association with cancer. What is known already: Endometriosis is a chronic condition with a plethora of presentations in terms of not only the occurrence of lesions, but also the presence of signs and symptoms. The most important symptoms include pain and infertility. Study design size duration: The guideline was developed according to the structured methodology for development of ESHRE guidelines. After formulation of key questions by a group of experts, literature searches and assessments were performed. Papers published up to 1 December 2020 and written in English were included in the literature review. Participants/materials setting methods: Based on the collected evidence, recommendations were formulated and discussed within specialist subgroups and then presented to the core guideline development group (GDG) until consensus was reached. A stakeholder review was organized after finalization of the draft. The final version was approved by the GDG and the ESHRE Executive Committee. Summary answer: The current guideline provides 109 recommendations on diagnosis, treatments for pain and infertility, management of disease recurrence, asymptomatic or extrapelvic disease, endometriosis in adolescents and postmenopausal women, prevention and the association with cancer. What is known already: Endometriosis is a chronic condition with a plethora of presentations in terms of not only the occurrence of lesions, but also the presence of signs and symptoms. The most important symptoms include pain and infertility. Study design size duration: The guideline was developed according to the structured methodology for development of ESHRE guidelines. After formulation of key questions by a group of experts, literature searches and assessments were performed. Papers published up to 1 December 2020 and written in English were included in the literature review. Participants/materials setting methods: Based on the collected evidence, recommendations were formulated and discussed within specialist subgroups and then presented to the core guideline development group (GDG) until consensus was reached. A stakeholder review was organized after finalization of the draft. The final version was approved by the GDG and the ESHRE Executive Committee. Main results and the role of chance: This guideline aims to help clinicians to apply best care for women with endometriosis. Although studies mostly focus on women of reproductive age, the guideline also addresses endometriosis in adolescents and postmenopausal women. The guideline outlines the diagnostic process for endometriosis, which challenges laparoscopy and histology as gold standard diagnostic tests. The options for treatment of endometriosis-associated pain symptoms include analgesics, medical treatments and surgery. Non-pharmacological treatments are also discussed. For management of endometriosis-associated infertility, surgical treatment and/or medically assisted reproduction are feasible. While most of the more recent studies confirm previous ESHRE recommendations, there are five topics in which significant changes to recommendations were required and changes in clinical practice are to be expected. Limitations reasons for caution: The guideline describes different management options but, based on existing evidence, no firm recommendations could be formulated on the most appropriate treatments. Also, for specific clinical issues, such as asymptomatic endometriosis or extrapelvic endometriosis, the evidence is too scarce to make evidence-based recommendations. Wider implications of the findings: The guideline provides clinicians with clear advice on best practice in endometriosis care, based on the best evidence currently available. In addition, a list of research recommendations is provided to stimulate further studies in endometriosis. Study funding/competing interests: The guideline was developed and funded by ESHRE, covering expenses associated with the guideline meetings, with the literature searches and with the dissemination of the guideline. The guideline group members did not receive payments. C.M.B. reports grants from Bayer Healthcare and the European Commission; Participation on a Data Safety Monitoring Board or Advisory Board with ObsEva (Data Safety Monitoring Group) and Myovant (Scientific Advisory Group). A.B. reports grants from FEMaLE executive board member and European Commission Horizon 2020 grant; consulting fees from Ethicon Endo Surgery, Medtronic; honoraria for lectures from Ethicon; and support for meeting attendance from Gedeon Richter; A.H. reports grants from MRC, NIHR, CSO, Roche Diagnostics, Astra Zeneca, Ferring; Consulting fees from Roche Diagnostics, Nordic Pharma, Chugai and Benevolent Al Bio Limited all paid to the institution; a pending patent on Serum endometriosis biomarker; he is also Chair of TSC for STOP-OHSS and CERM trials. O.H. reports consulting fees and speaker's fees from Gedeon Richter and Bayer AG; support for attending meetings from Gedeon-Richter, and leadership roles at the Finnish Society for Obstetrics and Gynecology and the Nordic federation of the societies of obstetrics and gynecology. L.K. reports consulting fees from Gedeon Richter, AstraZeneca, Novartis, Dr KADE/Besins, Palleos Healthcare, Roche, Mithra; honoraria for lectures from Gedeon Richter, AstraZeneca, Novartis, Dr KADE/Besins, Palleos Healthcare, Roche, Mithra; support for attending meetings from Gedeon Richter, AstraZeneca, Novartis, Dr KADE/Besins, Palleos Healthcare, Roche, Mithra; he also has a leadership role in the German Society of Gynecological Endocrinology (DGGEF). M.K. reports grants from French Foundation for Medical Research (FRM), Australian Ministry of Health, Medical Research Future Fund and French National Cancer Institute; support for meeting attendance from European Society for Gynaecological Endoscopy (ESGE), European Congress on Endometriosis (EEC) and ESHRE; She is an advisory Board Member, FEMaLe Project (Finding Endometriosis Using Machine Learning), Scientific Committee Chair for the French Foundation for Research on Endometriosis and Scientific Committee Chair for the ComPaRe-Endometriosis cohort. A.N. reports grants from Merck SA and Ferring; speaker fees from Merck SA and Ferring; support for meeting attendance from Merck SA; Participation on a Data Safety Monitoring Board or Advisory Board with Nordic Pharma and Merck SA; she also is a board member of medical advisory board, Endometriosis Society, the Netherlands (patients advocacy group) and an executive board member of the World Endometriosis Society. E.S. reports grants from National Institute for Health Research UK, Rosetrees Trust, Barts and the London Charity; Royalties from De Gruyter (book editor); consulting fees from Hologic; speakers fees from Hologic, Johnson & Johnson, Medtronic, Intuitive, Olympus and Karl Storz; Participation in the Medicines for Women's Health Expert Advisory Group with Medicines and Healthcare Products Regulatory Agency (MHRA); he is also Ambassador for the World Endometriosis Society. C.T. reports grants from Merck SA; Consulting fees from Gedeon Richter, Nordic Pharma and Merck SA; speaker fees from Merck SA, all paid to the institution; and support for meeting attendance from Ferring, Gedeon Richter and Merck SA. The other authors have no conflicts of interest to declare more...
- Published
- 2022
- Full Text
- View/download PDF
5. Reply: ovarian suspension for longer than 36 h is necessary for temporary ovarian suspension to fulfil its remit
- Author
-
W. Hoo, A. Stavroulis, Alfred Cutner, Ertan Saridogan, Edward Tong, Davor Jurkovic, and K. Pateman
- Subjects
medicine.medical_specialty ,business.industry ,Rehabilitation ,Ovary ,Endometriosis ,Obstetrics and Gynecology ,Tissue Adhesions ,Surgery ,Gynecologic Surgical Procedures ,Reproductive Medicine ,medicine ,Humans ,Female ,Suspension (vehicle) ,business - Published
- 2014
6. Reply: Criticizing the effect of ovarian suspension on adhesions in laparoscopic surgery for endometriosis
- Author
-
Ertan Saridogan, K. Pateman, Davor Jurkovic, A. Stavroulis, W. Hoo, Alfred Cutner, and Edward Tong
- Subjects
Laparoscopic surgery ,medicine.medical_specialty ,business.industry ,General surgery ,medicine.medical_treatment ,Rehabilitation ,Ovary ,Endometriosis ,Obstetrics and Gynecology ,Tissue Adhesions ,medicine.disease ,Gynecologic Surgical Procedures ,Reproductive Medicine ,medicine ,Humans ,Female ,Suspension (vehicle) ,business - Published
- 2014
7. Does ovarian suspension following laparoscopic surgery for endometriosis reduce postoperative adhesions? An RCT
- Author
-
Kate Pateman, Davor Jurkovic, Alfred Cutner, Andreas Stavroulis, W. Hoo, George Pandis, Ertan Saridogan, and Edward Tong
- Subjects
Laparoscopic surgery ,medicine.medical_specialty ,medicine.medical_treatment ,Endometriosis ,Ovary ,Tissue Adhesions ,law.invention ,Abdominal wall ,Gynecologic Surgical Procedures ,Randomized controlled trial ,Double-Blind Method ,law ,Medicine ,Humans ,Laparoscopy ,Pelvis ,Ultrasonography ,medicine.diagnostic_test ,business.industry ,General surgery ,Pelvic pain ,Rehabilitation ,Obstetrics and Gynecology ,medicine.disease ,medicine.anatomical_structure ,Reproductive Medicine ,Female ,medicine.symptom ,business - Abstract
STUDY QUESTION Is temporary ovarian suspension following laparoscopic surgery for severe pelvic endometriosis an effective method for reducing the prevalence of postoperative ovarian adhesions? SUMMARY ANSWER Temporary ovarian suspension for 36-48 h following laparoscopic treatment of severe endometriosis does not result in a significant reduction of postoperative ovarian adhesions. WHAT IS KNOWN ALREADY Pelvic adhesions often develop following laparoscopic surgery for severe pelvic endometriosis. Adhesions can cause chronic pelvic pain and fertility problems compromising the success of treatment. Small observational studies suggested that temporary postoperative ovarian suspension to the abdominal wall may significantly reduce the prevalence of postoperative ovarian adhesions. STUDY DESIGN, SIZE, DURATION This was a prospective within group comparison double-blind RCT. We recruited premenopausal women with severe pelvic endometriosis who required extensive laparoscopic surgery with preservation of the uterus and ovaries. Severity of the disease and eligibility for inclusion were determined at surgery. A total of 55 women were randomized to unilateral ovarian suspension for 36-48 h, 52 of which were included in the final analysis. Both ovaries were routinely suspended to the anterior abdominal wall during surgery. At the end of the operation, each woman was randomized to having only one ovary suspended postoperatively. The suture suspending the contralateral ovary was cut and a new transabdominal suture was inserted to act as a placebo. Both sutures were removed 36-48 h after surgery prior to discharge. Three months after surgery, all women attended for a detailed transvaginal ultrasound scan to assess ovarian mobility. Both the women and the ultrasound operators were blinded as to the side of postoperative ovarian suspension. The primary outcome was the prevalence of ovarian adhesions as described on ultrasound examination. Secondary outcomes were the severity of adhesions and the presence and intensity of postoperative pain. PARTICIPANTS/MATERIALS, SETTING, METHODS All 55 participants had severe pelvic endometriosis confirmed at laparoscopy. As each participant had only one of their ovaries suspended at the end of surgery, they acted as their own control. MAIN RESULTS AND THE ROLE OF CHANCE The median interval between ovarian suspension and postoperative scan was 99 days (interquartile range 68-114). There was no significant difference (P = 0.23) in the prevalence of postoperative ovarian adhesions between the suspended (20/52) and unsuspended (27/52) side (38.5 versus 51.9%) [odds ratio 0.56 (95% confidence interval 0.22-1.35)]. LIMITATIONS, REASONS FOR CAUTION Ovaries were suspended postoperatively for 36-48 h. Longer suspension could result in lower prevalence of postoperative adhesions. WIDER IMPLICATIONS OF THE FINDINGS The value of temporary ovarian suspension in women having surgery for mild-to-moderate endometriosis should be investigated further. The potential benefits of other adhesion prevention strategies, such as surgical barrier agents, in women undergoing surgical treatment for severe pelvic endometriosis should also be explored. STUDY FUNDING/COMPETING INTERESTS E.S. received honoraria from Ethicon for provision of training to healthcare professionals and consultancy fees from Bayer. W.H. was supported by the research fund provided by the Gynaecology Ultrasound Centre, London UK. A.C. is on the advisory board for surgical innovations for which he receives an annual honorarium. A.C. also received support for courses and education from Storz and Johnson and Johnson and support for clinical nursing from Covidien and Lotus. The other authors declared no competing interests. TRIAL REGISTRATION NUMBER Current Controlled Trials ISRCTN24242218. more...
- Published
- 2014
8. Can high histological confirmation rates be achieved for pelvic endometriosis?
- Author
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E Benjamin, Ertan Saridogan, A.I. Stavroulis, and Alfred Cutner
- Subjects
medicine.medical_specialty ,Biopsy ,Endometriosis ,Pelvic Pain ,Severity of Illness Index ,Severity of illness ,medicine ,Humans ,Laparoscopy ,Retrospective Studies ,Pelvic endometriosis ,medicine.diagnostic_test ,Obstetrics ,business.industry ,Pelvic pain ,Obstetrics and Gynecology ,Retrospective cohort study ,Histology ,medicine.disease ,Female ,Radiology ,medicine.symptom ,business - Abstract
This paper aims to determine the correlation between the diagnosis of endometriosis on the basis of the visualisation at laparoscopy and the histological diagnosis. Histological confirmation rates vary in the current literature. We retrospectively reviewed 160 patients over 2 years, who had laparoscopy for pelvic pain or suspected endometriosis. Our results showed higher histological confirmation rate compared with other studies. In addition, the use of CD10 IHC may increase detection rates further when the diagnosis is suspected but not confirmed by routine histology. Diagnosis of endometriosis is essential as it can influence patients' management. more...
- Published
- 2009
- Full Text
- View/download PDF
9. Laparoscopic treatment of endometriosis in teenagers
- Author
-
Ertan Saridogan, Alfred Cutner, A.I. Stavroulis, and Sarah M. Creighton
- Subjects
Laparoscopic surgery ,Adult ,medicine.medical_specialty ,Adolescent ,medicine.medical_treatment ,Population ,Endometriosis ,Pelvic Pain ,medicine ,Humans ,education ,Laparoscopy ,Hydrosalpinx ,Retrospective Studies ,education.field_of_study ,Ovarian cyst ,medicine.diagnostic_test ,business.industry ,Pelvic pain ,Obstetrics and Gynecology ,medicine.disease ,Surgery ,Reproductive Medicine ,Adolescent Health Services ,Functional Ovarian Cyst ,Female ,medicine.symptom ,business - Abstract
Objectives To determine the frequency and severity of endometriosis in adolescent and teenager girls with chronic pelvic pain (CPP) who fail to respond to medical treatment and to evaluate the outcome of radical laparoscopic surgery for severe endometriosis. Design Retrospective review of case records of all girls under the age of 21 years who underwent diagnostic and/or operative laparoscopy for CPP unresponsive to medical treatment between January 2001 and December 2003. The operative findings and the response to surgery were retrospectively reviewed. Results Thirty-one girls were referred. No pelvic abnormalities were detected in 11 patients (35.5%). Endometriosis was detected in 11 (35.5%). Six had severe endometriosis. Other diagnoses included: non-functional non-endometriotic ovarian cyst (4 patients), functional ovarian cyst (1 patient), hydrosalpinx (bilateral, 1 patient; unilateral, 1 patient) and obstructed uterine horn (2 patients). Of those with severe disease all six were treated laparoscopically without complications. Five were rendered pain free and one had an improvement in symptoms. Conclusions Endometriosis can occur in adolescent and teenager girls. Laparoscopy should be carried out in all adolescents and teenagers with CPP unresponsive to medical treatment. This the first study reporting the outcome of radical excision treatment for severe endometriosis in this age group and early results are encouraging. more...
- Published
- 2005
10. Can high histological confirmation rates be achieved for pelvic endometriosis?
- Author
-
Stavroulis, A. I., Saridogan, E., Benjamin, E., and Cutner, A. S.
- Subjects
- *
FEMALE reproductive organ diseases , *LAPAROSCOPY , *HISTOLOGY , *ENDOMETRIOSIS , *ENDOMETRIAL diseases , *PELVIC diseases , *DISEASES , *MANAGEMENT - Abstract
This paper aims to determine the correlation between the diagnosis of endometriosis on the basis of the visualisation at laparoscopy and the histological diagnosis. Histological confirmation rates vary in the current literature. We retrospectively reviewed 160 patients over 2 years, who had laparoscopy for pelvic pain or suspected endometriosis. Our results showed higher histological confirmation rate compared with other studies. In addition, the use of CD10 IHC may increase detection rates further when the diagnosis is suspected but not confirmed by routine histology. Diagnosis of endometriosis is essential as it can influence patients' management. [ABSTRACT FROM AUTHOR] more...
- Published
- 2009
- Full Text
- View/download PDF
11. Laparoscopic treatment of endometriosis in teenagers
- Author
-
Stavroulis, A.I., Saridogan, E., Creighton, S.M., and Cutner, A.S.
- Subjects
- *
TEENAGERS , *ENDOMETRIOSIS , *PELVIC pain , *ENDOSCOPY - Abstract
Abstract: Objectives: To determine the frequency and severity of endometriosis in adolescent and teenager girls with chronic pelvic pain (CPP) who fail to respond to medical treatment and to evaluate the outcome of radical laparoscopic surgery for severe endometriosis. Design: Retrospective review of case records of all girls under the age of 21 years who underwent diagnostic and/or operative laparoscopy for CPP unresponsive to medical treatment between January 2001 and December 2003. The operative findings and the response to surgery were retrospectively reviewed. Results: Thirty-one girls were referred. No pelvic abnormalities were detected in 11 patients (35.5%). Endometriosis was detected in 11 (35.5%). Six had severe endometriosis. Other diagnoses included: non-functional non-endometriotic ovarian cyst (4 patients), functional ovarian cyst (1 patient), hydrosalpinx (bilateral, 1 patient; unilateral, 1 patient) and obstructed uterine horn (2 patients). Of those with severe disease all six were treated laparoscopically without complications. Five were rendered pain free and one had an improvement in symptoms. Conclusions: Endometriosis can occur in adolescent and teenager girls. Laparoscopy should be carried out in all adolescents and teenagers with CPP unresponsive to medical treatment. This the first study reporting the outcome of radical excision treatment for severe endometriosis in this age group and early results are encouraging. [Copyright &y& Elsevier] more...
- Published
- 2006
- Full Text
- View/download PDF
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