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Start Over Author "McCarty NS" Topic endocarditis, bacterial

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1. Leukocytoclastic vasculitis associated with endocarditis in a patient with transposition of the great arteries and mechanical valve replacement.

Author

Riehle C, Scharf GM, Sieweke JT, Zauner F, Flierl U, Treptau J, Zormpas C, Senf J, McCarty NS, Bauersachs J, Sedding DG, and Westhoff-Bleck M

Subjects
Adult, Female, Heart Valve Prosthesis, Humans, Postoperative Complications, Staphylococcal Infections complications, Endocarditis, Bacterial complications, Transposition of Great Vessels complications, Vasculitis, Leukocytoclastic, Cutaneous etiology
Abstract

Immunological vascular phenomena can be the initial manifestation of bacterial infection and endocarditis. Here, we report a rare case of leukocytoclastic vasculitis without immune complexes or cryoglobulinemia in a patient with infective endocarditis, congenital heart disease, and a prior mechanical valve replacement. The patient completely recovered following antibiotic therapy, and skin lesions disappeared without immune suppression, which suggested infection-mediated vasculitis. While the treatment of leukocytoclastic vasculitis typically involves immunosuppressive therapy, the treatment for infection-mediated vasculitis is eradication of the infection., (Copyright © 2017 Elsevier Inc. All rights reserved.)

Published
2017
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