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Your search keyword '"Shichinohe K"' showing total 2 results
Start Over Author "Shichinohe K" Topic encephalomyocarditis virus
2 results on '"Shichinohe K"'

1. Effect of rearing conditions on encephalomyocarditis (EMC) virus-induced diabetes in mice.

Author

Shichinohe K, Shimizu M, Asakawa M, and Ishizaki M

Subjects
Animals, Germ-Free Life, Male, Mice, Animal Husbandry, Animals, Laboratory, Diabetes Mellitus, Experimental etiology, Encephalomyocarditis virus
Abstract

To compare the incidence in the diabetic syndrome in mice reared under sterile and non-sterile conditions, both conventional and SPF DBA/2 N male mice were inoculated intraperitoneally with two doses (10(4) TCID50/0.1 ml or 10(5) TCID50/0.1 ml) of encephalomyocarditis (EMC) virus M variant. The incidence of diabetic symptoms was higher in mice reared under sterile conditions than under non-sterile conditions. It appeared that a difference in animal rearing conditions would affect the sensitivity to EMC virus in mice.

Published
1990
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