1. Arbovirus infections in man in British Columbia.
- Author
-
Kettyls GD, Verrall VM, Wilton LD, Clapp JB, Clarke DA, and Rublee JD
- Subjects
- Adolescent, Adult, Animals, Arboviruses immunology, Brain microbiology, British Columbia, Child, Colorado Tick Fever epidemiology, Colorado Tick Fever immunology, Complement Fixation Tests, Encephalitis Virus, St. Louis immunology, Encephalitis Virus, Western Equine immunology, Encephalitis Virus, Western Equine isolation & purification, Encephalitis, Arbovirus epidemiology, Encephalitis, Arbovirus immunology, Encephalomyelitis, Equine immunology, Female, Hemagglutination Inhibition Tests, Horses, Humans, Male, Neutralization Tests, Arbovirus Infections epidemiology, Encephalomyelitis, Equine epidemiology
- Abstract
During the summer of 1971, the first laboratory-proved cases of acute encephalitis in man due to any of the known arboviruses occurred in the south-central region of British Columbia. Five human cases of encephalitis with two deaths were diagnosed; three of these patients, including one of the fatalities, were proven in the laboratory to have contracted western equine encephalitis.During 1968 and 1969, a human serum survey undertaken in approximately 2000 life-long residents of the province discovered low levels of hemagglutinin-inhibiting and/or complement-fixing as well as neutralizing antibodies for western equine encephalitis, St. Louis encephalitis, Powassan encephalitis, California encephalitis and Colorado tick fever. Evidence of recent sub-clinical infection was detected in some cases.
- Published
- 1972