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Structurally diverse 3,3′-thiopyrrolidonyl spirooxindoles bearing three contiguous stereogenic centers can be smoothly prepared via domino Michael/cyclization reaction using quinine as chiral catalyst. [ABSTRACT FROM AUTHOR]

Attractive features of this protocol are the utilization of readily available substrates, reagents, and catalysts, as well as simplicity and mild conditions. [ABSTRACT FROM AUTHOR]

A diagram is presented which explains the chemical process of organocatalytic asymmetric Michael addition of 3-Pyrrolyloxindoles to β-Phthalimidonitroethene for the synthesis of 3,3′-Disubstituted Oxindoles bearing contiguous 3,α,β-Triamino functionality.

The products are formed with excellent diastereo and enantioselectivities. [ABSTRACT FROM AUTHOR]

Chemical equation related to Asymmetric Michael Reaction of Arylacetyl Phosphonates to Nitroalkenes with Bifunctional Amine-Thiourea Catalyst Bearing Multiple-Hydrogen-Bond Donor by M.L. Zhang and colleagues published in the "Tetrahedron" periodical is presented.

An abstract of the article "Organocatalytic Asymmetric Henry Reaction of 1H-Pyrrole-2,3-diones with Bifunctional Amine-Thiourea Catalysts Bearing Multiple Hydrogen-Bond Donors" by K. Kobayashi and colleagues is presented.

An abstract of the article "Organocatalytic Asymmetric Michael/Cyclization Cascade Reactions of 3-Hydroxyoxindoles/3-Aminooxindoles with α,β-Unsaturated Acyl Phosphonates for the Construction of Spirocylic Oxindole-γ-lactones/lactams" by Chen L and colleagues is presented.

The method proves superior to previously developed protocols, thus providing variously substituted polycyclic spirooxindoles in virtually quantitative yields with excellent diastereo- and enantioselectivities. [ABSTRACT FROM AUTHOR]

The reaction tolerates aryl, but no alkyl substituted butenolides and aryl, hetaryl, alkyl, and carboxyl-substituted 2-enoylpyridines. [ABSTRACT FROM AUTHOR]

An abstract of the article "Enantioselective Synthesis of 3,3-Disubstituted Oxindoles Bearing Two Different Heteroatoms at the C3 Position by Organocatalyzed Sulfenylation and Selenenylation of 3-Pyrrolyl-oxindoles" by Y. You and colleagues is presented.

Review: [57 refs. [ABSTRACT FROM AUTHOR]

The scalable and efficient method provides various polycyclic spirooxindoles with three contiguous chiral centers, two of which are quarternary, in excellent yields and with high to excellent dia- and enantioselectivities. [ABSTRACT FROM AUTHOR]

A broad range of complex 3,3′-disubstituted oxindoles bearing two stereogenic centers are obtained in high yields and with high to excellent diastereo- and enantioselectivities. [ABSTRACT FROM AUTHOR]

Spirocyclic oxindoles are obtained by the title cyclization reaction with good to excellent diastereo- and enantioselectivities. [ABSTRACT FROM AUTHOR]

A squaramide-substituted cinchona alkaloid is successfully applied as catalyst for the synthesis of chiral oxindoles such as (III) and (V) by Michael addition of 3-pyrrolyloxindoles with nitroalkenes. [ABSTRACT FROM AUTHOR]

Crucial for the enantiomeric excess is the presence of an ortho-substituent on one of the two aromatic rings. [ABSTRACT FROM AUTHOR]

The absolute configuration of the products is not determined. [ABSTRACT FROM AUTHOR]

The article presents chemical equations related to article "Organocatalytic Asymmetric Double Michael Reaction of Nazarov Reagents with Alkylidene Azlactones for the Construction of Spiro-Fused Cyclohexanone/5-Oxazolone System" by J. Zuo and others, published in periodical "Tetrahedron" in 2014.

An abstract of the article "Quinine-Catalyzed Asymmetric Domino Michael-Cyclization Reaction for the Synthesis of Spirocyclic Oxindoles Bearing Two Spiro Quaternary Centers and Three Consecutive Stereocenters," by Bao-Dong Cui and colleagues is presented.

Chemical equations for article "Asymmetric Synthesis of β-Hydroxy-α-amino Phosphonic Acid Derivatives via Organocatalytic Direct Aldol Reaction of &#945-Isothiocyanato Phosphonates with Aldehydes" by W.Y. Han, and others, published in "Journal of Organic Chemistry" in 2013 are presented.

This method yields 3-aminooxindoles with adjacent quaternary and tertiary stereocenters in good yields and with good diastereo- and enantioselectivities under mild reaction conditions. [ABSTRACT FROM AUTHOR]

A novel L-serine derived catalyst is investigated for the stereoselective hydrosilylation of α-acetamido-β-enamino esters. [ABSTRACT FROM AUTHOR]

The preparation of thiols (III) proceeds with reasonable diastereo- and enantioselectivity. [ABSTRACT FROM AUTHOR]

Optimized conditions including optically active thioureas allow the synthesis of the title compounds in very short reaction times. [ABSTRACT FROM AUTHOR]

The article presents the steps of the chemical equations involved in a cascade michael/cyclization process with amino-thiocarbamate catalysts.

An abstract related to the synthesis of a series of novel chiral Lewis base catalysts is presented.