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Your search keyword '"Katsushima, S"' showing total 4 results
Start Over Author "Katsushima, S" Topic embolization, therapeutic
4 results on '"Katsushima, S"'

2. Hepatic neoplasms: effects of transcatheter arterial embolization on coagulation and fibrinolysis.

Author

Katsushima S, Oi H, Nakagawa K, Iida Y, Hidaka A, Hatabu H, Kusui T, and Konishi J

Subjects
Adult, Aged, Blood Coagulation Tests, Carcinoma, Hepatocellular blood, Female, Fibrinogen analysis, Humans, Liver Neoplasms blood, Male, Middle Aged, Platelet Count, Blood Coagulation physiology, Carcinoma, Hepatocellular therapy, Disseminated Intravascular Coagulation etiology, Embolization, Therapeutic adverse effects, Fibrinolysis physiology, Liver Neoplasms therapy
Abstract

Forty-eight patients with hepatic malignancy (47 with hepatocellular carcinoma, one with metastatic colon carcinoma), who underwent transcatheter arterial embolization (TAE) for treatment of hepatic neoplasms, were investigated to determine the effects of TAE on coagulation and fibrinolysis. TAE was followed by a significant decrease in the platelet count (P less than .001); a prolongation of prothrombin time (P less than .001); an early increase in levels of fibrinopeptide A (P less than .01), fibrinopeptide B beta-15-42 (P less than .001), and fibrin(ogen) degradation products (P less than .001); and a delayed increase in the fibrinogen level (P less than .001), without a significant prolongation of the activated partial thromboplastin time. In the three patients who developed disseminated intravascular coagulation (DIC) after TAE, a reduction of both the platelet count and fibrinogen level occurred significantly earlier and in a more severe form than in the other patients without DIC; this reduction preceded the onset of the characteristic symptoms of DIC. Data suggested that close monitoring of platelet count and fibrinogen level is important for early detection of DIC following TAE.

Published
1990
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3. [Changes in blood coagulation and fibrinolysis after transcatheter arterial chemoembolization in hepatocellular carcinoma].

Author

Katsushima S, Takeuchi R, Inokuma T, Hidaka A, Matsuda K, Kawaguchi Y, Ohi H, Nakagawa K, Fujino M, and Natori H

Subjects
Carcinoma, Hepatocellular therapy, Female, Humans, Liver Neoplasms therapy, Male, Middle Aged, Blood Coagulation, Carcinoma, Hepatocellular blood, Disseminated Intravascular Coagulation etiology, Embolization, Therapeutic adverse effects, Fibrinolysis, Liver Neoplasms blood
Published
1987
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4. Hepatic neoplasms: effects of transcatheter arterial embolization on coagulation and fibrinolysis

Author

Akinari Hidaka, T. Kusui, Hiroto Hatabu, Katsushima S, H Oi, K Nakagawa, Yasuhiro Iida, and Junji Konishi

Subjects
Adult, Male, medicine.medical_specialty, Carcinoma, Hepatocellular, medicine.medical_treatment, Fibrinogen, Gastroenterology, Fibrin, hemic and lymphatic diseases, Internal medicine, Fibrinolysis, medicine, Humans, Radiology, Nuclear Medicine and imaging, Blood Coagulation, Aged, Blood coagulation test, Disseminated intravascular coagulation, Prothrombin time, medicine.diagnostic_test, biology, Platelet Count, business.industry, Arterial Embolization, Liver Neoplasms, Disseminated Intravascular Coagulation, Middle Aged, medicine.disease, Embolization, Therapeutic, Surgery, biology.protein, Female, Blood Coagulation Tests, business, medicine.drug, Partial thromboplastin time
Abstract

Forty-eight patients with hepatic malignancy (47 with hepatocellular carcinoma, one with metastatic colon carcinoma), who underwent transcatheter arterial embolization (TAE) for treatment of hepatic neoplasms, were investigated to determine the effects of TAE on coagulation and fibrinolysis. TAE was followed by a significant decrease in the platelet count (P less than .001); a prolongation of prothrombin time (P less than .001); an early increase in levels of fibrinopeptide A (P less than .01), fibrinopeptide B beta-15-42 (P less than .001), and fibrin(ogen) degradation products (P less than .001); and a delayed increase in the fibrinogen level (P less than .001), without a significant prolongation of the activated partial thromboplastin time. In the three patients who developed disseminated intravascular coagulation (DIC) after TAE, a reduction of both the platelet count and fibrinogen level occurred significantly earlier and in a more severe form than in the other patients without DIC; this reduction preceded the onset of the characteristic symptoms of DIC. Data suggested that close monitoring of platelet count and fibrinogen level is important for early detection of DIC following TAE.

Published
1990

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