Search

A novel C–N bond activation strategy was established by developing new organic photoredox catalyst (Cz-NI-Ph), which provides a concise approach for the synthesis of amides from tertiary amines.

A metal-free amino-heteroarylation of unactivated olefins via new organic photoredox catalysis was reported, providing a concise and efficient approach for the rapid synthesis of various δ (β, ε)-amino ketones under mild conditions. A series of mechanistic experiments and DFT calculations indicate that this transformation undergoes a photoredox catalytic sequential radical addition/functional group migration process.

A metal-free C(sp3)-H phosphorylation of saturated aza-heterocycles via the merger of organic photoredox and Bronsted acid catalyses was established under mild conditions. This protocol provided straightforward and economic access to a variety of valuable α-phosphoryl cyclic amines by using commercially available diarylphosphine oxide reagents. In addition, the D-A fluorescent molecule DCQ was used for the first time as a photocatalyst and exhibited an excellent photoredox catalytic efficiency in this transformation. A series of mechanistic experiments and DFT calculations demonstrated that this transformation underwent a sequential visible light photoredox catalytic oxidation/nucleophilic addition process.