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Your search keyword '"Xiangzhang Tao"' showing total 2 results
Start Over Author "Xiangzhang Tao" Topic electrocatalysis
2 results on '"Xiangzhang Tao"'

1. Reductive deaminative cross-coupling of alkyl bistriflimides enabled by electrocatalysis.

Author

Xiangzhang Tao, Wooseok Lee, Zhimin Xu, Hui Shu, Qing Wang, Shengyang Ni, Yi Pan, Sungwoo Hong, and Yi Wang

Subjects
*HALOALKANES, *ARYL halides, *DENSITY functional theory, *ORGANIC synthesis, *ALKYL group, *ELECTROPHILES, *ELECTROCATALYSIS
Abstract

We present a versatile nickel-electrocatalytic deaminative cross-coupling platform for the efficient construction of C(sp3)-C(sp3) and C(sp3)-C(sp2) bonds from readily available alkyl bistriflimides. This methodology involves the assembly of two leaving groups on alkyl amines to form alkyl bistriflimides, followed by their effective coupling with a wide range of alkyl halides, alkyl pseudohalides, aryl halides, and alkenyl halides under electrochemical reductive conditions. Moreover, the successful application of electrochemical reductive relay cross-coupling and transition metal-free cross-electrophile coupling further demonstrates the versatility of alkyl bistriflimides as valuable building blocks in organic synthesis. Combined control experiments and density functional theory calculations provide insights into the reaction pathway and the crucial role of iodide in the catalytic process. [ABSTRACT FROM AUTHOR]

Published
2024
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2. Electrochemical C–N bond activation for deaminative reductive coupling of Katritzky salts

Author

Xin Yuan, Shengyang Ni, Xiangzhang Tao, Yi Pan, Linyu Kong, Yu Mao, Jiang-Kai Qiu, Yeqing Liu, Yi Wang, and Kai Guo

Subjects
Molecular diffusion, Multidisciplinary, Chemistry, Science, General Physics and Astronomy, Synthetic chemistry methodology, General Chemistry, Electron hole, Electrolyte, Electrosynthesis, Electrochemistry, Combinatorial chemistry, General Biochemistry, Genetics and Molecular Biology, Article, Catalysis, Reagent, Surface modification, Electrocatalysis
Abstract

Electrosynthesis has received great attention among researchers in both academia and industry as an ideal technique to promote single electron reduction without the use of expensive catalysts. In this work, we report the electrochemical reduction of Katritzky salts to alkyl radicals by sacrificing the easily accessible metal anode. This catalyst and electrolyte free platform has broad applicability to single electron transfer chemistry, including fluoroalkenylation, alkynylation and thiolation. The deaminative functionalization is facilitated by the rapid molecular diffusion across microfluidic channels, demonstrating the practicality that outpaces the conventional electrochemistry setups., Electrochemical transformations use electrons and electron holes instead of chemical oxidants and reductants as reagents. Here, the authors report an electrochemical reductive deaminative cross-coupling of Katrizky salts with various radical acceptors, including examples of fluoroalkenylation, alkynylation and thiolation.

Published
2021

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