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Background: Aortic dissection is a rare but potentially lethal disorder and may be associated with electrocardiogram (ECG) changes. In this study, we aim to investigate ECG-related parameters alongside clinical presentations of type A aortic dissection to come up with the predictive factors for the severity of the disease and its mortality rate., Methods: In this retrospective study, 201 patients with type A aortic dissection were studied between March 2015 and March 2020. Two expert cardiologists blinded to the diagnosis studied former and new patients' ECGs and recorded changes., Results: Two-hundred and one patients, including 143 (71.1%) men and 58 (28.9%) women, presented with acute dissection of the aorta, were studied. Forty-four (21.8%) and 84 (41.7%) patients had ST-segment elevation and depression in ECG, respectively. Bivariate analysis revealed that higher heart rate (p = 0.006), longer QTc (p = 0.044), and ST-segment elevation in aVR lead (p = 0.044) were associated with mortality in the patients. Multivariate regression showed higher heart rate (OR = 1.022, CI = 1.003-1.041, p = 0.012) and ST-segment elevation in aVR (OR = 4.854, CI = 2.255-10.477, p < 0.001) were independently associated with increased odds of mortality in aortic dissection patients. ROC curve analysis showed heart rate equal to or >60 per minute (AUC = 0.625, sensitivity = 86%, specificity = 10%, p = 0.019) and ST-segment elevation in aVR >0.5 mm (AUC = 0.854, sensitivity = 75%, specificity = 92%, p < 0.001) were associated with a higher mortality rate., Conclusion: Heart rate equal or >60 and ST-segment elevation >0.5 mm in aVR lead can be used as predictive factors for mortality of patients with type A aortic dissection., Competing Interests: Declaration of Competing Interest The authors declare no competing interests., (Copyright © 2023 Elsevier Inc. All rights reserved.)

Background: Cardiac dysfunction is a serious complication of cirrhosis which is usually asymptomatic. We investigated the clinical and electrocardiographic (ECG)‐related factors among patients with cirrhosis and our aim was to find any associations between ECG changes and the etiology of cirrhosis, as well as Child‐Pugh score. Hypothesis: We hypothesized that some ECG‐related factors, particularly prolonged QT interval, are more common in patients with cirrhosis. Also, these factors are associated with the severity of cirrhosis, measured by the Child‐Pugh score. Methods: From April 2019 to December 2022, we reviewed admitted patients to Namazi and Abu‐Ali Sina hospitals, Shiraz, Iran. Patients with confirmed diagnosis of cirrhosis and without concurrent disorders affecting the cardiovascular system were selected. Clinical and ECG‐related data were then extracted for participants, and Child‐Pugh score was calculated. Results: A total of 425 patients were included; the median age was 36 years, and 245 patients (57.6%) were men. Cryptogenic and primary sclerosing cholangitis were the most common etiologies. Prolonged QT followed by early transitional zone were the most common ECG changes (24.7% and 19.8%, respectively), which were significantly associated with the etiology of cirrhosis and Child‐Pugh class. Conclusions: Prolonged QT interval and presence of early transitional zone in patients with cirrhosis may indicate cardiac dysfunction, necessitating further evaluations. [ABSTRACT FROM AUTHOR]

Introduction: Left atrial appendage aneurysm is an infrequent abnormality presenting as atrial tachyarrhythmia, progressive dyspnea, atypical chest pain, and systemic thromboembolism. Surgical excision is considered to prevent fatal complications, even in asymptomatic cases. The present study aimed to report a 20-year-old male who presented with sudden onset palpitation and dyspnea. Case Presentation: The case was really novel, because congenital left atrial appendage aneurysm was accompanied by dilated cardiomyopathy and Left Ventricular (LV) non-compaction. Electrocardiography (ECG) showed atrial fibrillation with Rapid Ventricular Response (RVR) secondary to a massive congenital left atrial appendage aneurysm. At first, left-sided weakness was diagnosed. In the next Computed Tomography (CT) scan performed in the hospital, right temporoparietal hypodensity was detected, which was in favor of right Middle Cerebral Artery (MCA) territory infarction that progressed with hemorrhagic transformation. Conclusion: The patient did not accept surgical treatment and was discharged with medical therapy (oral anticoagulants and antiarrhythmic medications). He was expired as a result of multiple strokes. [ABSTRACT FROM AUTHOR]