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This paper presents a wearable sensor architecture for frequency-multiplexed electrical impedance tomography (EIT) and synchronous multilead electrocardiogram (ECG) data acquisition. The system is based on a novel electronic sensing architecture, called cooperative sensors, that significantly reduces the cabling complexity and enables flexible EIT stimulation and measurement patterns. The cooperative-sensor architecture was initially designed for ECG and has been extended for multichannel bioimpedance measurement. This approach allows for an adjustable EIT stimulation pattern via frequency-division multiplexing. This paper also shows a calibration procedure as well as EIT system noise performance assessment. Preliminary measurements on a healthy volunteer showed the ability of the wearable system to measure EIT data synchronously with multilead ECG. Ventilation-related and heartbeat-related EIT images were reconstructed, demonstrating the feasibility of the proposed architecture for non-invasive cardiovascular monitoring.

Many cardiorespiratory physiological signals can be measured from the chest skin. When measured at many spots, some of them like EIT (Electrical Impedance Tomography) produce images. Classical approaches cannot practically be used to make wearables with a large number of sensors, because the sensing points are connected to a bulky centralized electronics box in a star arrangement. The solution is to use cooperative sensors. A vest embedding 51 multi-signal sensors designed for COPD (Chronic Obstructive Pulmonary Disease) patients is described as example.

Objective Development of wearable medical technology for remote monitoring of patients suffering from chronic lung diseases may improve the care, therapy and outcome of these patients. Approach A multimodal system using wearable sensors for the acquisition of multiple biosignals (electrical bioimpedance of the chest for electrical impedance tomography and respiratory rate assessment, peripheral oxygen saturation, chest sounds, electrocardiography for heart rate measurement, body activity, and posture) was developed and validated in a prospective, monocentric study on 50 healthy subjects. The subjects were studied under different types of ventilation (tidal and deep breathing, forced full expiration maneuver) and during increased body activity and posture changes. The major goals were to assess the functionality by determining the presence and plausibility of the signals, comfort of wearing and safety of the vest. Main results All intended signals were recorded. Streaming of selected signals and wireless download of complete data sets were functional. Electrical impedance tomography recordings revealed good to excellent quality of detection of ventilation-related impedance changes in 34 out of 50 participants. Respiratory and heart rates were reliably detected and generally in physiological ranges. Peripheral oxygen saturation values were unphysiologically low. The chest sound recordings did not show waveforms allowing meaningful analysis of lung sounds. Body activity and posture were correctly identified. The comfort of wearing and the vest properties were positively rated. No adverse events occurred. Significance Albeit the full functionality of the current vest design was not established, the study confirmed the feasibility of remote functional chest monitoring with a marked increase in clinically relevant information compared to existing systems.