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Learning objectives Background Findings and procedure details Conclusion Personal information and conflict of interest References, Learning objectives: To use MRI findings as a retrospective learning resource to improve the performance of CT diagnosing. To emphasize the importance of correlating the findings obtained by MRI and CT. To explain possible sources of error and useful practices to...

Learning objectives Background Findings and procedure details Conclusion Personal information and conflict of interest References, Learning objectives: To explain the systemic thrombotic complications that can be associate with the evolution of the COVID-19 disease. To show the most frequent imaging manifestations of systemic thrombotic events in order to help radiologists identify them when...

Learning objectives Background Findings and procedure details Conclusion Personal information and conflict of interest References, Learning objectives: To define the Syndrome of Combined Pulmonary Fibrosis and Emphysema, by reviewing the terminology, definitions, characteristics and imaging features that characterize it. To summarize and simplify diagnostic criteria for CPFE. To illustrate the...

PMCID: PMC4482672, [Background]: Precise temporal and spatial expression of the clustered Hox genes is essential for patterning the developing embryo. Temporal activation of Hox genes was shown to be cluster-autonomous. However, gene clustering appears dispensable for spatial colinear expression. Generally, a set of Hox genes expressed in a group of cells instructs these cells about their fate such that the differential expression of Hox genes results in morphological diversity. The spatial colinearity is considered to rely both on local and long-range cis regulation. [Results]: Here, we report on the global deregulation of HoxA and HoxD expression patterns upon inactivation of a subset of HOXA and HOXD proteins. [Conclusions]: Our data suggest the existence of a >self-regulation> mechanism, a process by which HOX proteins establish and/or maintain the spatial domains of the Hox gene family and we propose that the functionally dominant HOX proteins could contribute to generating the spatial parameters of Hox expression in a given tissue, i.e., HOX controlling the establishment of the ultimate HOX code., Grant sponsor: the Spanish Government; Grant number: BFU2011-24972; Grant sponsor: the Canadian Institutes for Health Research; Grant number: MOP-82880; Grant number: 126110. This work was supported by the Spanish Government to M.R. and by the Canadian Institutes for Health Research as well as the Canada Research Chair program to M.K. R.S was supported by a Formación Profesorado Universitario fellowship from the Spanish Ministry of Science and Innovation and currently supported by the Angelo Pizzagalli postdoctoral fellowship.

La Seguridad del Paciente es una máxima a la que las organizaciones sanitarias cada vez prestan mayor atención; y poder garantizarla pasa por tratar de conseguir la excelencia en el cuidado. Para conseguir este objetivo, la práctica es algo fundamental, siendo la simulación clínica, en todas sus variantes, una herramienta muy valiosa para mejorar multitud de habilidades, con una incorporación cada vez mayor en la metodología docente de centros universitarios y sanitarios. La simulación ha evolucionado en las últimas décadas, mucho más rápido en los últimos años, gracias a los avances tecnológicos y las múltiples ventajas que ofrece. El aprendizaje y la evaluación en enfermería mediante la simulación en general, y la de alta fidelidad en particular, aunque conlleva el empleo de numerosos recursos, goza de gran aceptación entre alumnos e instructores en simulación, cumple todas las fases del aprendizaje experiencial y es la opción para la práctica de las habilidades necesarias ante situaciones críticas. Al diseñar adecuadamente un escenario de simulación, éste se convierte en una herramienta con un gran potencial docente. Grado en Enfermería