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Your search keyword '"Laine, Jaana"' showing total 3 results
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3 results on '"Laine, Jaana"'

1. Metsä talouden ja arvojen risteyksessä

Author

Laine, Jaana M, Laine, Jaana, Fellman, Susanna, Hannikainen, Matti, Ojala, Jari, Talous- ja sosiaalihistoria, Kestävyystieteen instituutti (HELSUS), and Poliittisten, yhteiskunnallisten ja alueellisten muutosten tohtoriohjelma

Subjects
education, 5200 Muut yhteiskuntatieteet, 511 Kansantaloustiede
Published
2019

2. Muuttuva kulutusyhteiskunta ja sen symbolit

Author

Autio, Minna, Laine, Jaana, Fellman, Susanna, Hannikainen, Matti, Ojala, Jari, Kasvatustieteiden osasto, Kasvatustieteellinen tiedekunta, Forest Bioeconomy, Business and Sustainability, Yliopiston johto, and Opettajien akatemia

Subjects
516 Kasvatustieteet, education, 5200 Muut yhteiskuntatieteet
Published
2019

3. Assessment of labelled products with different radioanalytical methods: study on 18F-fluorination reaction of 4-[18F]fluoro-N-[2-[1-(2-methoxyphenyl)-1-piperazinyl]ethyl-N-2-pyridinyl-benzamide (p-[18F]MPPF)

Author

Kim Bergström, Tiina Lipponen, Jaana Laine, Olof Solin, Outi Perhola, Teija Koivula, Eeva-Liisa Kämäräinen, Koivula, Teija, Laine, Jaana, Lipponen, Tiina, Perhola, Outi, Kämäräinen, Eeva-Liisa, Bergström, Kim, Solin, Olof, University of Helsinki, Department of Chemistry, University of Helsinki, Department of Chemistry (-2009), University of Helsinki, Laboratory of Radiochemistry (Dep. of Chemistry) (-2009), and University of Helsinki, Faculty of Pharmacy

Subjects
Health, Toxicology and Mutagenesis, education, 116 Chemical sciences, Mass spectrometry, High-performance liquid chromatography, 030218 nuclear medicine & medical imaging, Analytical Chemistry, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, MPPF, Liquid chromatography–mass spectrometry, Radiology, Nuclear Medicine and imaging, Benzamide, Hplc method, Spectroscopy, Radioanalytical methods, Chromatography, Chemistry, Radiolabelling, Public Health, Environmental and Occupational Health, Pollution, Fluorine-18, LC-MS, Nuclear Energy and Engineering, Microwave heating, Retention time, 030217 neurology & neurosurgery
Abstract

The serotonin receptor 5-HT1A ligand 4-( 18 F) fluoro-N-(2-(1-(2-methoxyphenyl)-1-piperazinyl)ethyl-N- 2-pyridinyl-benzamide (p-( 18 F)MPPF) was produced by a simplified method of Le Bars et al. Traditional oil bath heating was compared to microwave heating. Various radioanalytical methods, radio-Thin Layer Chromatogra- phy (TLC), High Pressure Liquid Chromatography (HPLC) and Mass Spectrometry (MS), were compared in the evaluation of the labelled product(s). The crude reaction mixture consisted of p-( 18 F)MPPF and 2-4 radioactive by-products eluting after the product fraction, and the reverse-phase HPLC method failed occasionally to sepa- rate p-( 18 F)MPPF from the radioactive by-product with close retention time. The heating method had no significant effect on the composition of labelled by-products. In LC-(ESI)-MS analysis of p-( 18 F)MPPF the labelled product was identified with m/z ratio of 435 ((M ? H ? )). The other

Published
2010

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