8 results on '"Inaba, Shinji"'
Search Results
2. Usefulness of transthoracic Doppler echocardiography for noninvasive assessment of coronary blood flow in a patient with symptomatic myocardial bridging.
- Author
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Inaba S, Okayama H, Higashi H, Nishimura K, Inoue K, Ogimoto A, and Higaki J
- Subjects
- Adrenergic beta-Antagonists therapeutic use, Angina Pectoris drug therapy, Angina Pectoris physiopathology, Bisoprolol therapeutic use, Blood Flow Velocity, Coronary Angiography methods, Female, Follow-Up Studies, Hemodynamics physiology, Humans, Middle Aged, Myocardial Bridging complications, Risk Assessment, Severity of Illness Index, Treatment Outcome, Angina Pectoris etiology, Coronary Circulation physiology, Echocardiography methods, Myocardial Bridging diagnostic imaging
- Abstract
Myocardial bridging (MB) is a congenital anomaly characterized by systolic compression of the tunnelled arterial segment. MB may cause myocardial ischaemia due to abnormal coronary blood flow. We report a case of MB in which transthoracic Doppler echocardiography was used to evaluate the long-term effect of beta-blocker therapy on abnormal coronary blood flow. In this case, beta-blocker therapy with bisoprolol (5.0 mg/day) for 1 month eliminated the patient's symptoms and normalized coronary blood flow through the tunnelled arterial segment.
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- 2011
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3. Restricted left atrial dilatation can visually differentiate cardiac amyloidosis from hypertrophic cardiomyopathy.
- Author
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Higashi, Haruhiko, Inoue, Katsuji, Inaba, Shinji, Nakao, Yasuhisa, Kinoshita, Masaki, Miyazaki, Shigehiro, Miyoshi, Toru, Akazawa, Yusuke, Kawakami, Hiroshi, Uetani, Teruyoshi, Aono, Jun, Nagai, Takayuki, Nishimura, Kazuhisa, Ikeda, Shuntaro, Saito, Makoto, and Yamaguchi, Osamu
- Subjects
CARDIAC amyloidosis ,HYPERTROPHIC cardiomyopathy ,ECHOCARDIOGRAPHY - Abstract
Aims: Cardiac amyloidosis (CA) is an infiltrative myocardial disease that occasionally mimics hypertrophic cardiomyopathy (HCM). The aim of this study is to investigate the discriminatory ability of visual assessment of left atrial (LA) function between CA and HCM on echocardiography. Methods and results: In total, 93 patients with cardiac magnetic resonance imaging (CMR)‐confirmed HCM and 34 with cardiac biopsy‐confirmed CA were retrospectively assessed. LA dilatation was assessed via echocardiography in an apical four‐chamber view. Visual assessment was performed to identify LA dilatation grade (preserved = 1, abnormal = 2, and restricted = 3) based on the extent of outward expansion in the LA reservoir phase. Regarding the reproducibility of visually assessing LA dilatation grade, the kappa values between intra‐ and inter‐observer measurements were 0.82 and 0.70, respectively. Of 127 participants, 57 (45%), 42 (33%), and 28 (22%) presented with LA dilatation Grades 1, 2, and 3, respectively. All 57 patients with preserved LA dilatation (Grade 1) had HCM, and 20 of 28 patients (71%) with restricted LA dilatation (Grade 3) presented with CA. Patients with CA had a higher LA dilatation grade than those with HCM (P < 0.01). LA emptying fraction and reservoir strain were also quantitatively evaluated. The area under the curves of LA dilatation grade (0.88) and LA emptying fraction (0.88) for differentiation of these two diseases were higher than that of LA reservoir strain (0.73) (P < 0.01, respectively). During follow‐up, nine patients with HCM and 16 with CA experienced cardiac event (cardiac death or hospitalization due to heart failure). In Kaplan–Meier analysis including both groups of HCM and CA, the incidence of cardiac events was higher in patients with restricted LA dilatation than in those with preserved or abnormal LA dilatation (log‐rank test, P < 0.01). Conclusions: Restricted LA dilatation is an indicator for the diagnosis of CA. Further, visual assessment of abnormal LA motion may facilitate diagnosis in patients with CA and high‐risk patients with HCM. [ABSTRACT FROM AUTHOR]
- Published
- 2021
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4. Usefulness of contrast computed tomography for diagnosing left ventricular thrombus before impella insertion.
- Author
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Nakao, Yasuhisa, Aono, Jun, Namiguchi, Kenji, Nishimura, Takashi, Izutani, Hironori, Higashi, Haruhiko, Inaba, Shinji, Nishimura, Kazuhisa, Inoue, Katsuji, Ikeda, Shuntaro, and Yamaguchi, Osamu
- Abstract
The Impella (Abiomed, Danvers, MA, USA) is a novel percutaneous heart pump device for left ventricular (LV) assistance; however, LV thrombus is a notable contraindication for this device. Contrast computed tomography assessment is useful for detecting LV thrombus and preventing thromboembolism in patients recommended for Impella use. < Learning objective: The Impella (Abiomed, Danvers, MA, USA) is a heart pump device which aspirates blood from a left ventricular (LV) cavity and ejects it into an ascending aorta. Therefore, LV thrombus should be explored before the Impella insertion to prevent systemic embolism. Generally, echocardiography is the first choice to detect LV thrombus. Given limited diagnostic sensitivity for detecting LV thrombus in echocardiography, contrast computed tomography might be a useful strategy for the patient targeting Impella insertion.> [ABSTRACT FROM AUTHOR]
- Published
- 2020
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5. Clinical significance of global two-dimensional strain as a surrogate parameter of myocardial fibrosis and cardiac events in patients with hypertrophic cardiomyopathy.
- Author
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Saito, Makoto, Okayama, Hideki, Yoshii, Toyofumi, Higashi, Haruhiko, Morioka, Hiroe, Hiasa, Go, Sumimoto, Takumi, Inaba, Shinji, Nishimura, Kazuhisa, Inoue, Katsuji, Ogimoto, Akiyoshi, Shigematsu, Yuji, Hamada, Mareomi, and Higaki, Jitsuo
- Subjects
HYPERTROPHIC cardiomyopathy ,CARDIOMYOPATHIES ,ECHOCARDIOGRAPHY ,HEART ventricle diseases ,BLOOD pressure ,HEART ventricles ,REGRESSION analysis ,T-test (Statistics) ,CONTRAST media ,DATA analysis software ,DESCRIPTIVE statistics ,KAPLAN-Meier estimator ,DISEASE complications ,PROGNOSIS - Abstract
Aims Late gadolinium enhancement (LGE) on contrast-enhanced magnetic resonance imaging (MRI) in hypertrophic cardiomyopathy (HCM) has been reported to be associated with myocardial fibrosis and cardiac events. In patients with HCM, two-dimensional (2D) strain can identify subclinical global systolic dysfunction despite normal left ventricular (LV) chamber function. Therefore, this study tested the hypothesis that global 2D strain could detect subtle myocardial fibrosis and serve as a novel prognostic parameter in HCM patients. Methods and results Echocardiography and MRI were performed in 48 consecutive patients with HCM and normal chamber function. We measured global longitudinal strain (GLS) in apical two-chamber, four-chamber, and long-axis views using speckle-tracking analysis. The extent of LGE (%LGE = LGE volume/total LV volume) and LV mass index were calculated by MRI using Simpson's rule and custom software. All patients were followed up for major cardiac events. Global longitudinal strain in patients with LGE was significantly lower than that without LGE (−11.8 ± 2.8 vs. −15.0 ± 1.7%, P < 0.001). Multivariate analysis showed that GLS was an independent predictor of %LGE (standard coefficient = 0.627, P < 0.001). During a mean follow-up period of 42 ± 12 months, five patients had cardiac events. When the patients were stratified based on the median level of GLS (−12.9%), all events were observed in the worse GLS group (P = 0.018). Conclusion These results suggest that global 2D strain might provide useful information on myocardial fibrosis and cardiac events in HCM patients with normal chamber function. [ABSTRACT FROM AUTHOR]
- Published
- 2012
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6. Direct measurement of radial strain in the inner-half layer of the left ventricular wall in hypertensive patients.
- Author
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Nishimura, Kazuhisa, Okayama, Hideki, Inoue, Katsuji, Saito, Makoto, Yoshii, Toyofumi, Hiasa, Go, Sumimoto, Takumi, Inaba, Shinji, Ogimoto, Akiyoshi, Funada, Jun-ichi, and Higaki, Jitsuo
- Subjects
LEFT heart ventricle ,HYPERTENSION ,ECHOCARDIOGRAPHY ,CARDIAC contraction ,CARDIAC hypertrophy ,MULTIVARIATE analysis - Abstract
Background: Two-dimensional speckle tracking echocardiography (2D-STE) is a novel technology that directly measures regional left ventricular (LV) wall contraction. This study aimed to directly measure inner-layer thickening (radial strain) of the LV using 2D-STE, and to examine the relationship between radial strain and the degree of hypertrophy. Methods: The study enrolled 63 untreated hypertensive patients with normal geometry (N group, n = 32) or concentric hypertrophy (CH group, n = 31 ), classified according to LV mass index (LVMI) and relative wall thickness (RWT). Thirty normotensive subjects (C group, n = 30) served as controls. Radial strain (e) in the inner half (ei) and all layers of the LV wall (sa) were calculated from the LV short-axis view by 2D-STE. Results: LV ejection fraction did not differ significantly among the groups. However, ei and sa were significantly lower in the CH group compared with the C and N groups (p < 0.01 ). A ratio of ei to ea was significantly lower in the CH group compared with the C and N groups (p < 0.01 ). A multivariate regression model that included midwall fractional shortening, E/e', LVMI, RWT, and LV ejection fraction showed that LVMI (p = 0.002) and RWT (p = 0.014) were independent predictors (R
2 = 0.59) of ei. Conclusion: Radial strain in the inner half layer of the LV wall decreases in parallel with the degrees of LV concentricity and hypertrophy in hypertensive patients. Radial strain in the inner half layer may identify subtle systolic dysfunction even in hypertensive patients with preserved LV chamber function. [ABSTRACT FROM AUTHOR]- Published
- 2012
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7. Pseudo-electrocardiographic regression of left ventricular hypertrophy in aortic stenosis: concomitant cardiac amyloidosis.
- Author
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Higashi, Haruhiko, Inaba, Shinji, Inoue, Katsuji, Ikeda, Shuntaro, and Yamaguchi, Osamu
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CARDIAC amyloidosis ,ECHOCARDIOGRAPHY ,LEFT ventricular hypertrophy ,AORTIC stenosis ,RADIONUCLIDE imaging ,ELECTROCARDIOGRAPHY - Published
- 2021
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8. The differences in left ventricular torsional behavior between patients with hypertrophic cardiomyopathy and hypertensive heart disease
- Author
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Saito, Makoto, Okayama, Hideki, Yoshii, Toyofumi, Hiasa, Go, Sumimoto, Takumi, Inaba, Shinji, Nishimura, Kazuhisa, Inoue, Katsuji, Ogimoto, Akiyoshi, Ohtsuka, Tomoaki, Funada, Jun-ichi, Shigematsu, Yuji, and Higaki, Jitsuo
- Subjects
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CARDIOMYOPATHIES , *HYPERTENSION , *LEFT heart ventricle , *TORSION abnormality (Anatomy) , *ECHOCARDIOGRAPHY , *DIAGNOSTIC imaging , *HYPERTROPHIC cardiomyopathy - Abstract
Abstract: Background: The aim of this study was to investigate the differences in left ventricular (LV) twisting behavior between patients with hypertrophic cardiomyopathy (HCM) and hypertensive heart disease (HHD). Methods: Forty-four patients with HCM (mean age, 63±15years), 35 patients with HHD (mean age, 63±13years) and 20 age and sex-matched control subjects were evaluated. After a standard echocardiographic examination, LV twist and twisting velocity profiles from apical and basal short-axis images were analyzed using two-dimensional speckle tracking imaging. Results: LV diastolic and systolic dimensions, and ejection fraction were not significantly different among the groups. LV mass index and early diastolic mitral annular velocity were not significantly different between the HCM and HHD groups. The peak torsion in the HCM and HHD groups was significantly greater than that in the control group. The peak untwisting velocity in the HCM group was comparable with that in the control group. However, when the peak untwisting velocity was corrected by peak torsion, this ratio was significantly decreased in the HCM group compared with the values in the HHD and control groups. The time to peak untwisting velocity in the HCM group was significantly longer than the values in the HHD and control groups. Conclusions: These results suggest that enhanced peak torsion in HCM may improve untwisting behavior, but this mechanism fails to fully compensate for impaired untwisting behavior compared with HHD. [Copyright &y& Elsevier]
- Published
- 2011
- Full Text
- View/download PDF
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