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4. Kanamycin dosage and levels in ear and other organs.

Author

Stupp H, Rauch S, Sous H, Brun JP, and Lagler F

Subjects
Animals, Brain metabolism, Dose-Response Relationship, Drug, Drug Administration Schedule, Ear, Inner metabolism, Guinea Pigs, Kanamycin blood, Kanamycin pharmacokinetics, Liver metabolism, Myocardium metabolism, Time Factors, Ear, Inner analysis, Kanamycin administration & dosage
Published
1967
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8. [Iodine distribution in the internal ear].

Author

Juhn SK and Rauch S

Subjects
Animals, Brain metabolism, Guinea Pigs, Hearing Disorders metabolism, Humans, Injections, Intraperitoneal, Iodine blood, Iodine Isotopes, Liver metabolism, Pancreas metabolism, Salivary Glands metabolism, Thyroid Gland metabolism, Ear, Inner metabolism, Iodine metabolism
Published
1967

9. [Progress in the biochemistry of the internal ear].

Author

Rauch S

Subjects
Animals, Cell Membrane Permeability, Ear, Inner enzymology, Guinea Pigs, Labyrinthine Fluids physiology, Potassium metabolism, Proteins metabolism, Ear, Inner metabolism, Labyrinthine Fluids metabolism
Published
1972

22. Kanamycin dosage and levels in ear and other organs

Author

S. Rauch, H. Sous, H. Stupp, J. P. Brun, and F. Lagler

Subjects
Blood level, medicine.medical_specialty, Time Factors, medicine.drug_class, Antibiotics, Guinea Pigs, Drug Administration Schedule, Kanamycin, medicine, Animals, Intensive care medicine, Short duration, Dose-Response Relationship, Drug, business.industry, Myocardium, Brain, General Medicine, Surgery, Otorhinolaryngology, Liver, Streptomycin, Ear, Inner, business, medicine.drug
Abstract

THE BASIC STREPTOMYCES antibiotics, streptomycin and kanamycin, are valuable and effective means in the hands of a physician. In many cases their use is indispensible, despite the danger of a toxic damage to the inner ear. The physician is therefore always faced with the weighty question of how these antibiotics are to be dosed in order to avoid possible damage. It is difficult not only to estimate the amount of the individual dosage that may be prescribed but also the sequence of the injections. Even today, as with other antibiotics as well, treatment with daily injections prevails. Treatment only at intervals recommended by several authors, is only seldom tried. Berger and Wehrle, 1 viewing the short duration of the blood level of antibiotics consider more frequent injections of every six hours necessary to the maintenance of therapeutically effective blood concentrations. This suggestion should be considered critically. In using toxic antibiotics

Published
1967

23. [Iodine distribution in the internal ear]

Author

S K, Juhn and S, Rauch

Subjects
Liver, Ear, Inner, Iodine Isotopes, Guinea Pigs, Thyroid Gland, Animals, Brain, Humans, Hearing Disorders, Pancreas, Injections, Intraperitoneal, Salivary Glands, Iodine
Published
1967

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