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Your search keyword '"Neelakantan, Pratap"' showing total 2 results
Start Over Author "Neelakantan, Pratap" Topic drug therapy
2 results on '"Neelakantan, Pratap"'

1. Excellent outcome after repeated changes of tyrosine kinase inhibitor therapy for chronic myeloid leukaemia in complete cytogenetic response due to minor side effects.

Author

Neelakantan, Pratap, Rezvani, Katayoun, May, Philippa, Gerrard, Gareth, Marco, Bua, Paliompeis, Christos, Reid, Alistair, Goldman, John, Marin, David, and Milojkovic, Dragana

Subjects
*HUMAN cytogenetics, *DRUG therapy, *IMATINIB, *TREATMENT of chronic myeloid leukemia, *CHRONIC myeloid leukemia, *PROTEIN-tyrosine kinase inhibitors, *GENETIC mutation, *GENETICS, *THERAPEUTICS
Abstract

The article focuses on a study which examines the cytogenetic response on Imatinib drug given to patients with chronic myeloid leukaemia as first line tyrosine kinase inhibitor (TKI) therapy. Topics discussed include strategy to minimize side effects of the drug using low cross-intolerance between different TKIs and change therapy, use of direct sequencing for the analysis of kinase domain mutations, and effect of the drug on patients with pleural effusion.

Published
2014
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2. Breast cancer metastasizing to the tongue.

Author

Neelakantan, Pratap, McLean, Sean R., Kenny, Sinead, Nathan, Myooran, Panchal, Lajja, Sandhu, Gurpreet, Coombes, Charles R., and Palmieri, Carlo

Subjects
*BREAST cancer, *TONGUE diseases, *MASTECTOMY, *DRUG therapy
Abstract

The article presents a case study of a 24-year-old woman with a metastic deposit on her tongue, secondary to primary breast cancer. A right mastectomy and axillary clearance with immediate reconstruction was performed. It states that the operative specimen showed a 38-mm, grade 2, invasive ductal carcinoma that gave weakly results for estrogen receptors. It reveals that after she received further chemotherapy she died from her disease a little over 2 years from the time of original presentation.

Published
2008

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