1. Human models for COVID‐19 research.
- Author
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Woodall, Maximillian N. J., Masonou, Tereza, Case, Katie‐Marie, and Smith, Claire M.
- Subjects
COVID-19 ,DRUG efficacy ,ANTIVIRAL agents ,DRUG development ,HUMAN beings - Abstract
Currently, therapeutics for COVID‐19 are limited. To overcome this, it is important that we use physiologically relevant models to reproduce the pathology of infection and evaluate the efficacy of antiviral drugs. Models of airway infection, including the use of a human infection challenge model or well‐defined, disease relevant in vitro systems can help determine the key components that perpetuate the severity of the disease. Here, we briefly review the human models that are currently being used in COVID‐19 research and drug development. [ABSTRACT FROM AUTHOR]
- Published
- 2021
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